IT1242004B - Derivati di isoindolo e loro sali, procedimenti per produrli ed agenteantitumore che li contiene. - Google Patents
Derivati di isoindolo e loro sali, procedimenti per produrli ed agenteantitumore che li contiene.Info
- Publication number
- IT1242004B IT1242004B IT48430A IT4843090A IT1242004B IT 1242004 B IT1242004 B IT 1242004B IT 48430 A IT48430 A IT 48430A IT 4843090 A IT4843090 A IT 4843090A IT 1242004 B IT1242004 B IT 1242004B
- Authority
- IT
- Italy
- Prior art keywords
- procedures
- salts
- produce
- agent containing
- tumor agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28554889 | 1989-11-01 | ||
JP20544390 | 1990-08-02 | ||
JP2-288069A JP3027599B2 (ja) | 1990-08-02 | 1990-10-25 | 新規なイソインドール誘導体およびその塩 |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9048430A0 IT9048430A0 (it) | 1990-10-31 |
IT9048430A1 IT9048430A1 (it) | 1992-05-01 |
IT1242004B true IT1242004B (it) | 1994-02-02 |
Family
ID=27328497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT48430A IT1242004B (it) | 1989-11-01 | 1990-10-31 | Derivati di isoindolo e loro sali, procedimenti per produrli ed agenteantitumore che li contiene. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5166204A (it) |
BE (1) | BE1004069A3 (it) |
CA (1) | CA2028960C (it) |
CH (1) | CH682151A5 (it) |
DE (1) | DE4034687C2 (it) |
DK (1) | DK261890A (it) |
FR (1) | FR2655345B1 (it) |
GB (1) | GB2239013B (it) |
IT (1) | IT1242004B (it) |
NL (1) | NL9002366A (it) |
SE (1) | SE509700C2 (it) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9215361D0 (en) * | 1992-07-20 | 1992-09-02 | Wellcome Found | Heterocyclic compounds |
ATE172463T1 (de) * | 1994-08-04 | 1998-11-15 | Hoffmann La Roche | Pyrrolocarbazol |
ATE246686T1 (de) * | 1995-03-09 | 2003-08-15 | Kyowa Hakko Kogyo Kk | Pyrrolocarbazolderivate |
FR2751655B1 (fr) * | 1996-07-26 | 1998-08-28 | Adir | Nouveaux derives de bis-imides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
DE19744257B4 (de) * | 1997-10-07 | 2004-04-15 | Zentaris Gmbh | Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen |
US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
US20060276497A1 (en) * | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
JPWO2003051883A1 (ja) * | 2001-12-18 | 2005-04-28 | 協和醗酵工業株式会社 | インドール誘導体 |
BR0309783A (pt) * | 2002-04-26 | 2005-03-22 | Warner Lambert Co | Inibidores de quinases de pontos de controlo (wee1 e chk1) |
CN100400529C (zh) * | 2003-10-08 | 2008-07-09 | 中国科学院化学研究所 | 含氟芳香族有机四酸二酐及制备方法和用途 |
US8076352B2 (en) * | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
US8940896B2 (en) * | 2004-03-15 | 2015-01-27 | Ptc Therapeutics, Inc. | Tetra-cyclic carboline derivatives useful in the inhibition of angiogenesis |
US7767689B2 (en) * | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
US8076353B2 (en) * | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
NZ588388A (en) | 2004-03-15 | 2012-05-25 | Ptc Therapeutics Inc | Carboline derivatives useful in the inhibition of angiogenesis |
CN101119717A (zh) * | 2004-11-23 | 2008-02-06 | Ptc医疗公司 | 用作抑制vegf产生的活性剂的取代酚 |
WO2006065479A2 (en) * | 2004-11-23 | 2006-06-22 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting vegf production |
CN110464722B (zh) * | 2019-06-06 | 2023-05-23 | 暨南大学 | 一类小分子化合物或其药学上可接受的盐在制备抗肿瘤转移药物中的应用 |
CN115594681B (zh) * | 2022-10-21 | 2024-06-18 | 广州六顺生物科技有限公司 | 一种异吲哚啉-1,3-二酮衍生物及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0303697B1 (en) * | 1987-03-09 | 1997-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance k-252 |
DE3833008A1 (de) * | 1988-09-29 | 1990-04-05 | Goedecke Ag | Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
-
1990
- 1990-10-30 GB GB9023568A patent/GB2239013B/en not_active Expired - Fee Related
- 1990-10-30 US US07/605,430 patent/US5166204A/en not_active Expired - Fee Related
- 1990-10-31 DK DK261890A patent/DK261890A/da not_active Application Discontinuation
- 1990-10-31 CA CA002028960A patent/CA2028960C/en not_active Expired - Fee Related
- 1990-10-31 IT IT48430A patent/IT1242004B/it active IP Right Grant
- 1990-10-31 BE BE9001032A patent/BE1004069A3/fr not_active IP Right Cessation
- 1990-10-31 CH CH3464/90A patent/CH682151A5/de not_active IP Right Cessation
- 1990-10-31 DE DE4034687A patent/DE4034687C2/de not_active Expired - Fee Related
- 1990-10-31 SE SE9003476A patent/SE509700C2/sv not_active IP Right Cessation
- 1990-10-31 NL NL9002366A patent/NL9002366A/nl not_active Application Discontinuation
- 1990-10-31 FR FR9013552A patent/FR2655345B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
SE509700C2 (sv) | 1999-02-22 |
SE9003476D0 (sv) | 1990-10-31 |
DE4034687A1 (de) | 1991-05-02 |
SE9003476L (sv) | 1992-05-01 |
IT9048430A0 (it) | 1990-10-31 |
CA2028960C (en) | 1999-01-19 |
BE1004069A3 (fr) | 1992-09-15 |
DK261890A (da) | 1991-05-02 |
GB9023568D0 (en) | 1990-12-12 |
FR2655345A1 (it) | 1991-06-07 |
GB2239013A (en) | 1991-06-19 |
IT9048430A1 (it) | 1992-05-01 |
DE4034687C2 (de) | 1999-12-02 |
GB2239013B (en) | 1993-06-02 |
US5166204A (en) | 1992-11-24 |
NL9002366A (nl) | 1991-06-03 |
CA2028960A1 (en) | 1991-05-02 |
CH682151A5 (it) | 1993-07-30 |
FR2655345B1 (it) | 1993-02-26 |
DK261890D0 (da) | 1990-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970829 |