NL8520265A - Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. - Google Patents

Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. Download PDF

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Publication number
NL8520265A
NL8520265A NL8520265A NL8520265A NL8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A
Authority
NL
Netherlands
Prior art keywords
gave
vitamin
ethyl acetate
mol
hexane
Prior art date
Application number
NL8520265A
Other languages
English (en)
Dutch (nl)
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL8520265A publication Critical patent/NL8520265A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL8520265A 1984-10-04 1985-08-19 Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. NL8520265A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
US8501571 1985-08-19
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same

Publications (1)

Publication Number Publication Date
NL8520265A true NL8520265A (nl) 1986-09-01

Family

ID=24637652

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8520265A NL8520265A (nl) 1984-10-04 1985-08-19 Derivaten van vitamine d en werkwijzen voor het bereiden daarvan.

Country Status (13)

Country Link
EP (1) EP0197949A1 (it)
JP (3) JPS62500301A (it)
AU (2) AU582789B2 (it)
BE (1) BE903376A (it)
CH (1) CH672920A5 (it)
DE (2) DE3590488T (it)
DK (5) DK154290C (it)
FR (1) FR2571369B1 (it)
GB (2) GB2167070B (it)
IE (1) IE58104B1 (it)
IT (1) IT1190401B (it)
NL (1) NL8520265A (it)
WO (1) WO1986002078A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206229A (en) * 1988-04-21 1993-04-27 Leo Pharmaceutical Products Ltd Vitamin d analogues
AU629831B2 (en) * 1988-04-29 1992-10-15 Wisconsin Alumni Research Foundation Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) * 1983-05-09 1984-11-22 Wisconsin Alumni Res Found PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS

Also Published As

Publication number Publication date
DK159389B (da) 1990-10-08
EP0197949A1 (en) 1986-10-22
DK15390A (da) 1990-01-19
DK177489A (da) 1989-04-13
IT8522359A0 (it) 1985-10-04
DK15290D0 (da) 1990-01-19
DE3590488C2 (it) 1992-10-01
DK15290A (da) 1990-01-19
GB2188932A (en) 1987-10-14
GB2188932B (en) 1988-09-01
JPH0689022B2 (ja) 1994-11-09
AU4776185A (en) 1986-04-17
JPH0569103B2 (it) 1993-09-30
AU605007B2 (en) 1991-01-03
GB8524479D0 (en) 1985-11-06
CH672920A5 (it) 1990-01-15
DK158989B (da) 1990-08-13
DK15390D0 (da) 1990-01-19
DK111188D0 (da) 1988-03-02
DK158989C (da) 1991-01-21
DK177489D0 (da) 1989-04-13
FR2571369A1 (fr) 1986-04-11
DK260086A (da) 1986-06-03
IE58104B1 (en) 1993-06-30
GB2167070B (en) 1988-09-01
GB2167070A (en) 1986-05-21
DK159389C (da) 1991-03-11
BE903376A (fr) 1986-02-03
JPH0635475B2 (ja) 1994-05-11
AU582789B2 (en) 1989-04-13
DK158990B (da) 1990-08-13
DK154290C (da) 1989-03-28
IE852443L (en) 1986-04-04
GB8709579D0 (en) 1987-05-28
JPS62500301A (ja) 1987-02-05
DK111188A (da) 1988-03-02
DK158991C (da) 1991-01-21
DE3590488T (de) 1986-10-09
FR2571369B1 (fr) 1987-12-04
JPH05222089A (ja) 1993-08-31
AU2761488A (en) 1989-06-08
DK260086D0 (da) 1986-06-03
DK158990C (da) 1991-01-21
WO1986002078A1 (en) 1986-04-10
JPH05178887A (ja) 1993-07-20
DK154290B (da) 1988-10-31
IT1190401B (it) 1988-02-16
DK158991B (da) 1990-08-13

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