DK111188D0 - Mellemprodukter til brug ved fremstillingen af vitamin-d-derivater - Google Patents

Mellemprodukter til brug ved fremstillingen af vitamin-d-derivater

Info

Publication number
DK111188D0
DK111188D0 DK111188A DK111188A DK111188D0 DK 111188 D0 DK111188 D0 DK 111188D0 DK 111188 A DK111188 A DK 111188A DK 111188 A DK111188 A DK 111188A DK 111188 D0 DK111188 D0 DK 111188D0
Authority
DK
Denmark
Prior art keywords
intermediates
vitamin
derivatives
production
Prior art date
Application number
DK111188A
Other languages
English (en)
Other versions
DK111188A (da
DK159389C (da
DK159389B (da
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK111188A publication Critical patent/DK111188A/da
Publication of DK111188D0 publication Critical patent/DK111188D0/da
Publication of DK159389B publication Critical patent/DK159389B/da
Application granted granted Critical
Publication of DK159389C publication Critical patent/DK159389C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK111188A 1984-10-04 1988-03-02 Cholestadien- eller -trienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af 24-homovitamin-d3-derivater DK159389C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
US8501571 1985-08-19
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same

Publications (4)

Publication Number Publication Date
DK111188A DK111188A (da) 1988-03-02
DK111188D0 true DK111188D0 (da) 1988-03-02
DK159389B DK159389B (da) 1990-10-08
DK159389C DK159389C (da) 1991-03-11

Family

ID=24637652

Family Applications (5)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (da) 1984-10-04 1986-06-03 Vitamin-d-derivater og farmaceutiske praeparater indeholdende disse
DK111188A DK159389C (da) 1984-10-04 1988-03-02 Cholestadien- eller -trienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af 24-homovitamin-d3-derivater
DK177489A DK158989C (da) 1984-10-04 1989-04-13 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK015390A DK158991C (da) 1984-10-04 1990-01-19 Cholestadienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater
DK015290A DK158990C (da) 1984-10-04 1990-01-19 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK260086A DK154290C (da) 1984-10-04 1986-06-03 Vitamin-d-derivater og farmaceutiske praeparater indeholdende disse

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK177489A DK158989C (da) 1984-10-04 1989-04-13 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater
DK015390A DK158991C (da) 1984-10-04 1990-01-19 Cholestadienderivater, der kan anvendes som mellemprodukter til brug ved fremstillingen af homovitamin-d3-derivater
DK015290A DK158990C (da) 1984-10-04 1990-01-19 Cholestadienderivat, der kan anvendes som mellemprodukt til brug ved fremstillingen af homovitamin-d3-derivater

Country Status (13)

Country Link
EP (1) EP0197949A1 (da)
JP (3) JPS62500301A (da)
AU (2) AU582789B2 (da)
BE (1) BE903376A (da)
CH (1) CH672920A5 (da)
DE (2) DE3590488C2 (da)
DK (5) DK154290C (da)
FR (1) FR2571369B1 (da)
GB (2) GB2167070B (da)
IE (1) IE58104B1 (da)
IT (1) IT1190401B (da)
NL (1) NL8520265A (da)
WO (1) WO1986002078A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2711161B2 (ja) * 1988-04-21 1998-02-10 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） 新規ビタミンｄ類似体
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
RU2057117C1 (ru) * 1988-04-29 1996-03-27 Висконсин Алюмни Рисерч Фаундейшн ГОМОЛОГИ 1α - ГИДРОКСИВИТАМИНА D3 С НЕНАСЫЩЕННОЙ БОКОВОЙ ЦЕПЬЮ, КОМПОЗИЦИЯ, СПОСОБСТВУЮЩАЯ СТИМУЛЯЦИИ И УСИЛЕНИЮ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА, СПОСОБ СТИМУЛЯЦИИ И УСИЛЕНИЯ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) * 1983-05-09 1984-11-22 Wisconsin Alumni Res Found PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS

Also Published As

Publication number Publication date
AU2761488A (en) 1989-06-08
GB2188932A (en) 1987-10-14
IT1190401B (it) 1988-02-16
GB2167070A (en) 1986-05-21
NL8520265A (nl) 1986-09-01
GB2188932B (en) 1988-09-01
JPH05222089A (ja) 1993-08-31
DK158990B (da) 1990-08-13
DK15290A (da) 1990-01-19
DK158989B (da) 1990-08-13
JPH0689022B2 (ja) 1994-11-09
BE903376A (fr) 1986-02-03
JPH0635475B2 (ja) 1994-05-11
IE58104B1 (en) 1993-06-30
DK158991B (da) 1990-08-13
AU605007B2 (en) 1991-01-03
DK111188A (da) 1988-03-02
FR2571369A1 (fr) 1986-04-11
GB8524479D0 (en) 1985-11-06
WO1986002078A1 (en) 1986-04-10
CH672920A5 (da) 1990-01-15
DK15390D0 (da) 1990-01-19
JPS62500301A (ja) 1987-02-05
DK154290C (da) 1989-03-28
DK260086A (da) 1986-06-03
DK177489A (da) 1989-04-13
DK158991C (da) 1991-01-21
DK159389C (da) 1991-03-11
IE852443L (en) 1986-04-04
EP0197949A1 (en) 1986-10-22
DK15390A (da) 1990-01-19
DK177489D0 (da) 1989-04-13
AU4776185A (en) 1986-04-17
DK154290B (da) 1988-10-31
DK159389B (da) 1990-10-08
IT8522359A0 (it) 1985-10-04
DK15290D0 (da) 1990-01-19
DE3590488T (de) 1986-10-09
DK158990C (da) 1991-01-21
GB8709579D0 (en) 1987-05-28
FR2571369B1 (fr) 1987-12-04
JPH05178887A (ja) 1993-07-20
DK158989C (da) 1991-01-21
AU582789B2 (en) 1989-04-13
DE3590488C2 (da) 1992-10-01
JPH0569103B2 (da) 1993-09-30
DK260086D0 (da) 1986-06-03
GB2167070B (en) 1988-09-01

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