DK416888D0 - Cephalosporinforbindelser, krystallinske derivater deraf, mellemprodukter til brug ved fremstilling af cephalosporinforbindelser og fremgangsmaader til fremstilling af cephalosporinforbindelser - Google Patents

Cephalosporinforbindelser, krystallinske derivater deraf, mellemprodukter til brug ved fremstilling af cephalosporinforbindelser og fremgangsmaader til fremstilling af cephalosporinforbindelser

Info

Publication number
DK416888D0
DK416888D0 DK416888A DK416888A DK416888D0 DK 416888 D0 DK416888 D0 DK 416888D0 DK 416888 A DK416888 A DK 416888A DK 416888 A DK416888 A DK 416888A DK 416888 D0 DK416888 D0 DK 416888D0
Authority
DK
Denmark
Prior art keywords
production
cephalosporine compounds
cephalosporine
compounds
crystallinic
Prior art date
Application number
DK416888A
Other languages
English (en)
Other versions
DK416888A (da
Inventor
Kazuo Kato
Kimihiro Murakami
Hidenori Mochizuki
Ei Mochida
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of DK416888D0 publication Critical patent/DK416888D0/da
Publication of DK416888A publication Critical patent/DK416888A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK416888A 1986-11-25 1988-07-25 Cephalosporinforbindelser, krystallinske derivater deraf, mellemprodukter til brug ved fremstilling af cephalosporinforbindelser og fremgangsmaader til fremstilling af cephalosporinforbindelser DK416888A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61280019A JPS63132893A (ja) 1986-11-25 1986-11-25 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
PCT/JP1987/000902 WO1988003924A1 (en) 1986-11-25 1987-11-20 Novel cephalosporin derivatives and their crystalline derivatives

Publications (2)

Publication Number Publication Date
DK416888D0 true DK416888D0 (da) 1988-07-25
DK416888A DK416888A (da) 1988-07-25

Family

ID=17619166

Family Applications (1)

Application Number Title Priority Date Filing Date
DK416888A DK416888A (da) 1986-11-25 1988-07-25 Cephalosporinforbindelser, krystallinske derivater deraf, mellemprodukter til brug ved fremstilling af cephalosporinforbindelser og fremgangsmaader til fremstilling af cephalosporinforbindelser

Country Status (13)

Country Link
US (1) US4866055A (da)
EP (1) EP0272487A1 (da)
JP (1) JPS63132893A (da)
KR (1) KR890700128A (da)
AU (2) AU598607B2 (da)
DK (1) DK416888A (da)
FI (1) FI883496A0 (da)
IL (1) IL84580A0 (da)
NZ (1) NZ222670A (da)
PH (1) PH24993A (da)
WO (1) WO1988003924A1 (da)
ZA (1) ZA878835B (da)
ZW (1) ZW21787A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI872879A (fi) * 1986-07-21 1988-01-22 Sankei Yakuhin Kk --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes.
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
NZ225383A (en) * 1987-08-07 1990-03-27 Sankei Yakuhin Kk Cephalosporin derivatives and pharmaceutical compositions
JPH0418056A (ja) * 1990-05-09 1992-01-22 Sanwa Kagaku Kenkyusho Co Ltd ポリイソプレン化合物及びその塩、これ等の製法並びにこれ等を有効成分とする消化性潰瘍治療剤
US5095012A (en) * 1990-08-23 1992-03-10 Bristol-Myers Squibb Company Antibiotic c-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
US5234920A (en) * 1990-08-23 1993-08-10 Bristol-Myers Squibb Company Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
EP1016646A1 (fr) * 1991-12-12 2000-07-05 Hoechst Marion Roussel Nouveaux produits intermédiaires pour la préparation de céphalosporines comportant en position 7 un radical benzyloxyimino substitué
IL105191A (en) * 1992-04-04 1998-08-16 Basf Ag Acids and aminooxymethylbenzoic acids and their preparation
KR100257129B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
DE102004024010A1 (de) * 2004-05-14 2005-12-01 Bayer Chemicals Ag Verfahren zur Herstellung von Difluorbenzo-1,3-dioxol-5-carbonsäurederivaten
US8698184B2 (en) 2011-01-21 2014-04-15 Cree, Inc. Light emitting diodes with low junction temperature and solid state backlight components including light emitting diodes with low junction temperature

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE566543A (da) * 1957-04-09
JPS503170B1 (da) * 1970-06-11 1975-01-31
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
NZ189245A (en) * 1976-01-23 1979-12-11 Roussel Uclaf Substituted 2-(2-amino-4-thiazoyl)-2-hydroxyimino-acetic acid derivatives
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
US4082912A (en) * 1976-06-30 1978-04-04 Bristol-Myers Company Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters
US4103085A (en) * 1977-02-24 1978-07-25 Bristol-Myers Company 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US4104469A (en) * 1977-04-15 1978-08-01 Bristol-Myers Company 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
AR231986A1 (es) * 1978-05-26 1985-04-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
DE3165922D1 (en) * 1980-03-28 1984-10-18 Biochemie Gmbh New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
US4316024A (en) * 1980-09-15 1982-02-16 Bristol-Myers Company Dioxo piperazine compounds
JPS6011917B2 (ja) * 1981-04-09 1985-03-28 山之内製薬株式会社 新規なセファロスポリン化合物
US4436912A (en) * 1981-09-08 1984-03-13 Eli Lilly And Company 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido cephalosporin antibiotics and intermediates therefor
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
US4526977A (en) * 1981-10-07 1985-07-02 American Home Products Corporation 2-(3-Amino-5-isoxazolyl)-2-oxyimino-acetic acids
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
DE3143537A1 (de) * 1981-11-03 1983-05-11 Hoechst Ag, 6230 Frankfurt Kristalline salze von cefodizim und verfahren zu ihrer herstellung
FR2517309A1 (fr) * 1981-12-01 1983-06-03 Sanofi Sa Nouveaux derives de cephalosporines substitues en position 3 par un groupe heterocycle thiomethyl; procede de preparation desdits composes et compositions pharmaceutiques en contenant
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
JPS5946292A (ja) * 1982-09-09 1984-03-15 Otsuka Chem Co Ltd ２−置換セフエム誘導体の製造法
JPS5973575A (ja) * 1982-10-05 1984-04-25 Shionogi & Co Ltd プロピニルアミノイソオキサゾ−ル誘導体
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
JPS59155391A (ja) * 1983-02-22 1984-09-04 Tanabe Seiyaku Co Ltd 新規セファロスポリン誘導体
JPS6066987A (ja) * 1983-09-20 1985-04-17 Takeda Chem Ind Ltd 抗生物質ｔａν−５４７，その製造法および微生物
US4600773A (en) * 1983-12-01 1986-07-15 Eli Lilly And Company Crystalline cephalexin hydrochloride monohydrate
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
JPS61126089A (ja) * 1984-11-26 1986-06-13 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体、その製法およびそれらを含有する抗菌剤
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
NZ215527A (en) * 1985-04-01 1989-06-28 Mochida Pharm Co Ltd Cephalosporin derivatives and pharmaceutical compositions
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives

Also Published As

Publication number Publication date
AU8163187A (en) 1988-05-26
ZA878835B (en) 1988-05-25
US4866055A (en) 1989-09-12
NZ222670A (en) 1990-08-28
AU6316790A (en) 1991-03-28
JPS63132893A (ja) 1988-06-04
KR890700128A (ko) 1989-03-02
IL84580A0 (en) 1988-04-29
FI883496A (fi) 1988-07-25
WO1988003924A1 (en) 1988-06-02
EP0272487A1 (en) 1988-06-29
ZW21787A1 (en) 1988-09-07
AU598607B2 (en) 1990-06-28
DK416888A (da) 1988-07-25
FI883496A0 (fi) 1988-07-25
PH24993A (en) 1990-12-26

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