DK467780A - Fremgangsmaade til fremstilling af 24,24-difluor25-hydrochlecalciferol og mellemprodukter til brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af 24,24-difluor25-hydrochlecalciferol og mellemprodukter til brug ved fremgangsmaaden

Info

Publication number
DK467780A
DK467780A DK467780A DK467780A DK467780A DK 467780 A DK467780 A DK 467780A DK 467780 A DK467780 A DK 467780A DK 467780 A DK467780 A DK 467780A DK 467780 A DK467780 A DK 467780A
Authority
DK
Denmark
Prior art keywords
procedure
hydrochlecalciferol
difluor25
intermediates
preparing
Prior art date
Application number
DK467780A
Other languages
English (en)
Other versions
DK156635C (da
DK156635B (da
Inventor
H F Deluca
N Ikekawa
Y Tanaka
Y Kobayashi
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK467780A publication Critical patent/DK467780A/da
Publication of DK156635B publication Critical patent/DK156635B/da
Application granted granted Critical
Publication of DK156635C publication Critical patent/DK156635C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK467780A 1979-03-05 1980-11-04 Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol DK156635C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/017,168 US4196133A (en) 1979-03-05 1979-03-05 24,24-Difluoro-25-hydroxycholecalciferol
US1716879 1979-03-05
US7900898 1979-10-15
PCT/US1979/000898 WO1980001915A1 (en) 1979-03-05 1979-10-15 24,24-difluoro-25-hydroxycholecalciferol

Publications (3)

Publication Number Publication Date
DK467780A true DK467780A (da) 1980-11-04
DK156635B DK156635B (da) 1989-09-18
DK156635C DK156635C (da) 1990-02-12

Family

ID=21781101

Family Applications (3)

Application Number Title Priority Date Filing Date
DK467780A DK156635C (da) 1979-03-05 1980-11-04 Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol
DK446482A DK156644C (da) 1979-03-05 1982-10-08 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien
DK425183A DK156726C (da) 1979-03-05 1983-09-19 3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK446482A DK156644C (da) 1979-03-05 1982-10-08 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien
DK425183A DK156726C (da) 1979-03-05 1983-09-19 3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Country Status (16)

Country Link
US (1) US4196133A (da)
JP (2) JPS6310946B2 (da)
AU (1) AU532388B2 (da)
BE (1) BE882036A (da)
CA (1) CA1157049A (da)
CH (2) CH654015A5 (da)
DK (3) DK156635C (da)
FR (2) FR2450814B1 (da)
GB (1) GB2044770B (da)
IE (1) IE49532B1 (da)
IL (1) IL58525A (da)
IT (1) IT1151077B (da)
NL (1) NL7920160A (da)
NZ (1) NZ191899A (da)
SE (1) SE8007427L (da)
WO (1) WO1980001915A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4254045A (en) * 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4564474A (en) * 1983-08-18 1986-01-14 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
US4500460A (en) * 1983-08-18 1985-02-19 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
IT1175607B (it) * 1983-08-18 1987-07-15 Wisconsin Alumni Res Found 23,23-difluoro-25-idrossi-e 1 alfa, 25-diidrossi-vitamina d3
JPS6253960A (ja) * 1985-05-30 1987-03-09 Taisho Pharmaceut Co Ltd ビタミンｄ↓３の誘導体
IL139241A0 (en) 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4028349A (en) * 1976-03-08 1977-06-07 Hoffmann-La Roche Inc. Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof
JPS595432B2 (ja) * 1976-11-09 1984-02-04 凸版印刷株式会社 容器の製造方法
US4188345A (en) * 1978-07-26 1980-02-12 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
FR2450814A1 (fr) 1980-10-03
DK156635C (da) 1990-02-12
DK156726B (da) 1989-09-25
JPS56500064A (da) 1981-01-22
IL58525A (en) 1983-02-23
IT1151077B (it) 1986-12-17
CH654015A5 (de) 1986-01-31
DK156644C (da) 1990-02-12
WO1980001915A1 (en) 1980-09-18
IT8020326A0 (it) 1980-03-03
DK156635B (da) 1989-09-18
JPS6310946B2 (da) 1988-03-10
GB2044770B (en) 1983-05-11
FR2455609A1 (fr) 1980-11-28
FR2455609B1 (da) 1983-07-01
FR2450814B1 (fr) 1986-04-11
AU5580980A (en) 1980-09-11
IE49532B1 (en) 1985-10-16
SE8007427L (sv) 1980-10-22
NZ191899A (en) 1984-11-09
GB2044770A (en) 1980-10-22
AU532388B2 (en) 1983-09-29
CA1157049A (en) 1983-11-15
IL58525A0 (en) 1980-01-31
JPS63183559A (ja) 1988-07-28
DK425183D0 (da) 1983-09-19
JPH0142944B2 (da) 1989-09-18
CH653018A5 (de) 1985-12-13
NL7920160A (nl) 1980-12-31
DK156726C (da) 1990-03-05
DK446482A (da) 1982-10-08
IE800420L (en) 1980-09-05
DK156644B (da) 1989-09-18
BE882036A (fr) 1980-07-01
US4196133A (en) 1980-04-01
DK425183A (da) 1983-09-19

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