DK436981A - Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved - Google Patents

Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved

Info

Publication number
DK436981A
DK436981A DK436981A DK436981A DK436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A
Authority
DK
Denmark
Prior art keywords
hydroxy26
hexafluor
cholecalciferol
intermediates
preparing
Prior art date
Application number
DK436981A
Other languages
English (en)
Inventor
H F Deluca
Y Tanaka
N Ikekawa
Y Kobayashi
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK436981A publication Critical patent/DK436981A/da
Priority to DK375484A priority Critical patent/DK375484D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK436981A 1980-02-04 1981-10-02 Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved DK436981A (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK375484A DK375484D0 (da) 1980-02-04 1984-08-02 3-hydroxy-26,26,26,27,27,27-hexafluor-cholest-5-en-25-ol-forbindelserog fremgangsmaade til fremstilling deraf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/118,149 US4248791A (en) 1980-02-04 1980-02-04 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
PCT/US1981/000035 WO1981002298A1 (en) 1980-02-04 1981-01-13 Ciferol 25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

Publications (1)

Publication Number Publication Date
DK436981A true DK436981A (da) 1981-10-02

Family

ID=22376765

Family Applications (1)

Application Number Title Priority Date Filing Date
DK436981A DK436981A (da) 1980-02-04 1981-10-02 Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved

Country Status (12)

Country Link
US (1) US4248791A (da)
AU (1) AU544294B2 (da)
BE (1) BE887344A (da)
CH (2) CH651295A5 (da)
DK (1) DK436981A (da)
FR (1) FR2477145B1 (da)
GB (2) GB2082586B (da)
IE (1) IE50815B1 (da)
IL (1) IL61930A (da)
IT (1) IT1194789B (da)
NZ (1) NZ196039A (da)
WO (1) WO1981002298A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4358406A (en) * 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
JPS59500864A (ja) * 1982-05-26 1984-05-17 ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン ２６，２６．２６，２７．２７，２７―ヘキサフルオロ―１α，２５―ジヒドロキシコレステロール化合物及びその製造方法
US4411833A (en) * 1982-05-26 1983-10-25 Wisconsin Alumni Research Foundation Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol
US4613594A (en) * 1984-11-16 1986-09-23 Hoffmann-La Roche Inc. Fluorinated vitamin D3 compounds
ZA859138B (en) * 1984-12-19 1986-08-27 Hoffmann La Roche Cholecalciferol derivatives
EP0205025A1 (en) * 1985-05-27 1986-12-17 Sumitomo Pharmaceuticals Company, Limited Fluorine derivatives of vitamin D3 and cell differentiation-inducing agents containing the same as an active ingredient
CA1314872C (en) 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same
JPH0764804B2 (ja) * 1986-04-25 1995-07-12 住友製薬株式会社 活性型ビタミンｄ３のフッ素誘導体
US4853378A (en) * 1986-10-20 1989-08-01 Sumitomo Chemical Company, Limited Fluorine derivatives of vitamin D3 and process for producing the same
JPS63196556A (ja) * 1987-02-10 1988-08-15 Taisho Pharmaceut Co Ltd 含フツ素ビタミンｄ誘導体
JPH0737476B2 (ja) * 1991-01-17 1995-04-26 ウイスコンシン アラムナイ リサーチ フオンデーシヨン ２６，２６，２６，２７，２７，２７−ヘキサフルオロ−１α，２５−ジヒドロキシコレステロール
BR9405735A (pt) * 1993-02-19 1995-12-05 Wisconsin Alumni Res Found Uso de 26,26,26,27,27,27-hexaflúor-1-alfa 25-dihidróxi colecalciferol para o tratamento de distúrbios do metabolismo do cálcio
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
CA2981549A1 (en) * 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
SG10201404883YA (en) 2009-08-14 2014-10-30 Berg Llc Vitamin d3 and analogs thereof for treating alopecia
CA2776464C (en) * 2009-10-02 2017-10-24 Wisconsin Alumni Research Foundation 1-desoxy-2-methylene-19-nor-vitamin d analogs and their uses
AU2014274099A1 (en) 2013-05-29 2015-12-24 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin D
US20200281944A1 (en) * 2017-11-17 2020-09-10 Mahmood Piraee Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

Also Published As

Publication number Publication date
GB2082586A (en) 1982-03-10
BE887344A (fr) 1981-06-01
IL61930A (en) 1984-11-30
IT1194789B (it) 1988-09-28
FR2477145A1 (fr) 1981-09-04
GB2068382A (en) 1981-08-12
GB2068382B (en) 1984-02-29
CH651295A5 (de) 1985-09-13
GB2082586B (en) 1983-10-05
IE810196L (en) 1981-08-04
FR2477145B1 (fr) 1985-09-20
WO1981002298A1 (en) 1981-08-20
IE50815B1 (en) 1986-07-23
NZ196039A (en) 1983-07-15
IL61930A0 (en) 1981-02-27
US4248791A (en) 1981-02-03
IT8119459A0 (it) 1981-02-02
CH652725A5 (de) 1985-11-29
AU6684681A (en) 1981-08-13
AU544294B2 (en) 1985-05-23

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