DK156726C - 3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien - Google Patents

3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Info

Publication number
DK156726C
DK156726C DK425183A DK425183A DK156726C DK 156726 C DK156726 C DK 156726C DK 425183 A DK425183 A DK 425183A DK 425183 A DK425183 A DK 425183A DK 156726 C DK156726 C DK 156726C
Authority
DK
Denmark
Prior art keywords
hydroxy
cholestane
difluoro
diene
Prior art date
Application number
DK425183A
Other languages
English (en)
Other versions
DK425183A (da
DK425183D0 (da
DK156726B (da
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Yoshiro Kobayashi
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK425183A publication Critical patent/DK425183A/da
Publication of DK425183D0 publication Critical patent/DK425183D0/da
Publication of DK156726B publication Critical patent/DK156726B/da
Application granted granted Critical
Publication of DK156726C publication Critical patent/DK156726C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK425183A 1979-03-05 1983-09-19 3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien DK156726C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1716879 1979-03-05
US06/017,168 US4196133A (en) 1979-03-05 1979-03-05 24,24-Difluoro-25-hydroxycholecalciferol
US7900898 1979-10-15
PCT/US1979/000898 WO1980001915A1 (en) 1979-03-05 1979-10-15 24,24-difluoro-25-hydroxycholecalciferol

Publications (4)

Publication Number Publication Date
DK425183A DK425183A (da) 1983-09-19
DK425183D0 DK425183D0 (da) 1983-09-19
DK156726B DK156726B (da) 1989-09-25
DK156726C true DK156726C (da) 1990-03-05

Family

ID=21781101

Family Applications (3)

Application Number Title Priority Date Filing Date
DK467780A DK156635C (da) 1979-03-05 1980-11-04 Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol
DK446482A DK156644C (da) 1979-03-05 1982-10-08 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien
DK425183A DK156726C (da) 1979-03-05 1983-09-19 3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK467780A DK156635C (da) 1979-03-05 1980-11-04 Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol
DK446482A DK156644C (da) 1979-03-05 1982-10-08 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Country Status (16)

Country Link
US (1) US4196133A (da)
JP (2) JPS6310946B2 (da)
AU (1) AU532388B2 (da)
BE (1) BE882036A (da)
CA (1) CA1157049A (da)
CH (2) CH654015A5 (da)
DK (3) DK156635C (da)
FR (2) FR2450814B1 (da)
GB (1) GB2044770B (da)
IE (1) IE49532B1 (da)
IL (1) IL58525A (da)
IT (1) IT1151077B (da)
NL (1) NL7920160A (da)
NZ (1) NZ191899A (da)
SE (1) SE8007427L (da)
WO (1) WO1980001915A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4254045A (en) * 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
US4307025A (en) * 1981-02-17 1981-12-22 Wisconsin Alumni Research Foundation 1α, 25-dihydroxy-2β-fluorovitamin D3
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
IT1175607B (it) * 1983-08-18 1987-07-15 Wisconsin Alumni Res Found 23,23-difluoro-25-idrossi-e 1 alfa, 25-diidrossi-vitamina d3
US4500460A (en) * 1983-08-18 1985-02-19 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
US4564474A (en) * 1983-08-18 1986-01-14 Wisconsin Alumni Research Foundation 23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
JPS6253960A (ja) * 1985-05-30 1987-03-09 Taisho Pharmaceut Co Ltd ビタミンｄ↓３の誘導体
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4028349A (en) * 1976-03-08 1977-06-07 Hoffmann-La Roche Inc. Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof
JPS595432B2 (ja) * 1976-11-09 1984-02-04 凸版印刷株式会社 容器の製造方法
US4188345A (en) * 1978-07-26 1980-02-12 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
CA1157049A (en) 1983-11-15
FR2455609B1 (da) 1983-07-01
FR2450814B1 (fr) 1986-04-11
GB2044770B (en) 1983-05-11
IL58525A0 (en) 1980-01-31
IL58525A (en) 1983-02-23
DK425183A (da) 1983-09-19
WO1980001915A1 (en) 1980-09-18
DK425183D0 (da) 1983-09-19
DK156635C (da) 1990-02-12
AU5580980A (en) 1980-09-11
DK156644B (da) 1989-09-18
DK446482A (da) 1982-10-08
DK156635B (da) 1989-09-18
DK156644C (da) 1990-02-12
JPS56500064A (da) 1981-01-22
CH653018A5 (de) 1985-12-13
IT1151077B (it) 1986-12-17
US4196133A (en) 1980-04-01
GB2044770A (en) 1980-10-22
IE800420L (en) 1980-09-05
CH654015A5 (de) 1986-01-31
JPH0142944B2 (da) 1989-09-18
AU532388B2 (en) 1983-09-29
DK467780A (da) 1980-11-04
NZ191899A (en) 1984-11-09
JPS63183559A (ja) 1988-07-28
DK156726B (da) 1989-09-25
FR2450814A1 (fr) 1980-10-03
NL7920160A (nl) 1980-12-31
SE8007427L (sv) 1980-10-22
IE49532B1 (en) 1985-10-16
JPS6310946B2 (da) 1988-03-10
FR2455609A1 (fr) 1980-11-28
IT8020326A0 (it) 1980-03-03
BE882036A (fr) 1980-07-01

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Legal Events

Date Code Title Description
ATS Application withdrawn
PBP Patent lapsed