DK56490D0 - Homocholestenderivater som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater - Google Patents

Homocholestenderivater som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater

Info

Publication number
DK56490D0
DK56490D0 DK056490A DK56490A DK56490D0 DK 56490 D0 DK56490 D0 DK 56490D0 DK 056490 A DK056490 A DK 056490A DK 56490 A DK56490 A DK 56490A DK 56490 D0 DK56490 D0 DK 56490D0
Authority
DK
Denmark
Prior art keywords
derivatives
homochol
homovitamin
intermediates
preparation
Prior art date
Application number
DK056490A
Other languages
English (en)
Other versions
DK56490A (da
DK162394B (da
DK162394C (da
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Heinrich K Schnoes
Voula Ostrem
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/739,332 external-priority patent/US4717721A/en
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK56490A publication Critical patent/DK56490A/da
Publication of DK56490D0 publication Critical patent/DK56490D0/da
Publication of DK162394B publication Critical patent/DK162394B/da
Application granted granted Critical
Publication of DK162394C publication Critical patent/DK162394C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK056490A 1985-01-17 1990-03-05 26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater DK162394C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US69215185A 1985-01-17 1985-01-17
US69215185 1985-01-17
US06/739,332 US4717721A (en) 1985-05-30 1985-05-30 Sidechain homo-vitamin D compounds with preferential anti-cancer activity
US73933285 1985-05-30
PCT/US1986/000093 WO1986004333A1 (en) 1985-01-17 1986-01-15 Vitamin d derivatives and methods for preparing same
US8600093 1986-01-15

Publications (4)

Publication Number Publication Date
DK56490A DK56490A (da) 1990-03-05
DK56490D0 true DK56490D0 (da) 1990-03-05
DK162394B DK162394B (da) 1991-10-21
DK162394C DK162394C (da) 1992-03-09

Family

ID=27104918

Family Applications (3)

Application Number Title Priority Date Filing Date
DK443186A DK157007C (da) 1985-01-17 1986-09-16 Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler
DK035889A DK159273C (da) 1985-01-17 1989-01-27 26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da) 1985-01-17 1990-03-05 26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK443186A DK157007C (da) 1985-01-17 1986-09-16 Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler
DK035889A DK159273C (da) 1985-01-17 1989-01-27 26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater

Country Status (7)

Country Link
EP (1) EP0211863B1 (da)
JP (3) JPH0737391B2 (da)
KR (1) KR910004337B1 (da)
AU (1) AU594662B2 (da)
DE (1) DE3687377T2 (da)
DK (3) DK157007C (da)
WO (1) WO1986004333A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
AU629831B2 (en) * 1988-04-29 1992-10-15 Wisconsin Alumni Research Foundation Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US4226770A (en) * 1978-02-10 1980-10-07 Kaiser Emil T Synthesis of steroids
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
CH665834A5 (de) * 1983-05-09 1988-06-15 Wisconsin Alumni Res Found Verfahren zur herstellung von 1alpha,25-dihydroxyliertem vitamin d(2) und verwandten verbindungen.
NL8520009A (nl) * 1984-01-30 1985-12-02 Wisconsin Alumni Res Found 1alfa.25-dihydroxy-22z-dehydrovitamine d verbinding.

Also Published As

Publication number Publication date
DK157007C (da) 1990-03-19
AU594662B2 (en) 1990-03-15
DK443186D0 (da) 1986-09-16
DK56490A (da) 1990-03-05
DK159273C (da) 1991-02-18
DK35889A (da) 1989-01-27
JPH0737391B2 (ja) 1995-04-26
JPH0635474B2 (ja) 1994-05-11
JPH05132499A (ja) 1993-05-28
AU5359786A (en) 1986-08-13
DK162394B (da) 1991-10-21
KR870700071A (ko) 1987-02-28
KR910004337B1 (ko) 1991-06-26
DK162394C (da) 1992-03-09
DK159273B (da) 1990-09-24
WO1986004333A1 (en) 1986-07-31
EP0211863B1 (en) 1992-12-30
DE3687377D1 (de) 1993-02-11
JPH06128160A (ja) 1994-05-10
DK157007B (da) 1989-10-30
DK443186A (da) 1986-09-16
DK35889D0 (da) 1989-01-27
JPH0678354B2 (ja) 1994-10-05
DE3687377T2 (de) 1993-04-29
JPH0649092A (ja) 1994-02-22
EP0211863A4 (en) 1987-03-16
EP0211863A1 (en) 1987-03-04

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