DK157007C - Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler - Google Patents

Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler

Info

Publication number
DK157007C
DK157007C DK443186A DK443186A DK157007C DK 157007 C DK157007 C DK 157007C DK 443186 A DK443186 A DK 443186A DK 443186 A DK443186 A DK 443186A DK 157007 C DK157007 C DK 157007C
Authority
DK
Denmark
Prior art keywords
compounds
pharmaceutical preparations
diseases
vitamin
cure
Prior art date
Application number
DK443186A
Other languages
English (en)
Other versions
DK443186D0 (da
DK157007B (da
DK443186A (da
Inventor
Hector F Deluca
Nobuo Ikekawa
Yoko Tanaka
Heinrich K Schnoes
Voula Ostrem
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/739,332 external-priority patent/US4717721A/en
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK443186D0 publication Critical patent/DK443186D0/da
Publication of DK443186A publication Critical patent/DK443186A/da
Publication of DK157007B publication Critical patent/DK157007B/da
Application granted granted Critical
Publication of DK157007C publication Critical patent/DK157007C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK443186A 1985-01-17 1986-09-16 Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler DK157007C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US69215185A 1985-01-17 1985-01-17
US69215185 1985-01-17
US06/739,332 US4717721A (en) 1985-05-30 1985-05-30 Sidechain homo-vitamin D compounds with preferential anti-cancer activity
US73933285 1985-05-30
US8600093 1986-01-15
PCT/US1986/000093 WO1986004333A1 (en) 1985-01-17 1986-01-15 Vitamin d derivatives and methods for preparing same

Publications (4)

Publication Number Publication Date
DK443186D0 DK443186D0 (da) 1986-09-16
DK443186A DK443186A (da) 1986-09-16
DK157007B DK157007B (da) 1989-10-30
DK157007C true DK157007C (da) 1990-03-19

Family

ID=27104918

Family Applications (3)

Application Number Title Priority Date Filing Date
DK443186A DK157007C (da) 1985-01-17 1986-09-16 Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler
DK035889A DK159273C (da) 1985-01-17 1989-01-27 26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da) 1985-01-17 1990-03-05 26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK035889A DK159273C (da) 1985-01-17 1989-01-27 26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da) 1985-01-17 1990-03-05 26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Country Status (7)

Country Link
EP (1) EP0211863B1 (da)
JP (3) JPH0678354B2 (da)
KR (1) KR910004337B1 (da)
AU (1) AU594662B2 (da)
DE (1) DE3687377T2 (da)
DK (3) DK157007C (da)
WO (1) WO1986004333A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
JPH0699454B2 (ja) * 1988-04-29 1994-12-07 ウィスコンシン・アルムナイ・リサーチ・ファウンデイション １α―ヒドロキシビタミンＤ同族体
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US4226770A (en) * 1978-02-10 1980-10-07 Kaiser Emil T Synthesis of steroids
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
AU568549B2 (en) * 1983-05-09 1988-01-07 Wisconsin Alumni Research Foundation Process for the preparation of 1a, 25-dihydroxylated vitamin d2 and related compounds
CH665835A5 (de) * 1984-01-30 1988-06-15 Wisconsin Alumni Res Found 1alpha,25-dihydroxy-22z-dehydrovitamin d-verbindung.

Also Published As

Publication number Publication date
EP0211863A1 (en) 1987-03-04
DK56490A (da) 1990-03-05
DK56490D0 (da) 1990-03-05
AU5359786A (en) 1986-08-13
KR870700071A (ko) 1987-02-28
EP0211863B1 (en) 1992-12-30
JPH0635474B2 (ja) 1994-05-11
JPH05132499A (ja) 1993-05-28
DK159273C (da) 1991-02-18
DK162394B (da) 1991-10-21
DK443186D0 (da) 1986-09-16
JPH0649092A (ja) 1994-02-22
DE3687377D1 (de) 1993-02-11
AU594662B2 (en) 1990-03-15
JPH0678354B2 (ja) 1994-10-05
EP0211863A4 (en) 1987-03-16
KR910004337B1 (ko) 1991-06-26
JPH06128160A (ja) 1994-05-10
DK162394C (da) 1992-03-09
WO1986004333A1 (en) 1986-07-31
DK159273B (da) 1990-09-24
DK157007B (da) 1989-10-30
DK443186A (da) 1986-09-16
DK35889D0 (da) 1989-01-27
DE3687377T2 (de) 1993-04-29
JPH0737391B2 (ja) 1995-04-26
DK35889A (da) 1989-01-27

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