DK147386D0 - Derivater af methylen-bisphosphonsyre, fremgangsmaade til fremstillingaf samme samt farmaceutisk sammensaetning - Google Patents

Derivater af methylen-bisphosphonsyre, fremgangsmaade til fremstillingaf samme samt farmaceutisk sammensaetning

Info

Publication number
DK147386D0
DK147386D0 DK147386A DK147386A DK147386D0 DK 147386 D0 DK147386 D0 DK 147386D0 DK 147386 A DK147386 A DK 147386A DK 147386 A DK147386 A DK 147386A DK 147386 D0 DK147386 D0 DK 147386D0
Authority
DK
Denmark
Prior art keywords
methylene
derivatives
procedure
preparation
pharmaceutical composition
Prior art date
Application number
DK147386A
Other languages
English (en)
Other versions
DK147386A (da
DK167808B1 (da
Inventor
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of DK147386D0 publication Critical patent/DK147386D0/da
Publication of DK147386A publication Critical patent/DK147386A/da
Application granted granted Critical
Publication of DK167808B1 publication Critical patent/DK167808B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK147386A 1984-07-31 1986-04-01 Methylen-bisphosphonsyrederivat, fremgangsmaade til fremstilling heraf samt farmaceutisk sammensaetning indeholdende disse derivater DK167808B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8419489 1984-07-31
GB848419489A GB8419489D0 (en) 1984-07-31 1984-07-31 Chemical compounds
PCT/DK1985/000071 WO1986000902A1 (en) 1984-07-31 1985-07-25 Derivatives of methylene-bisphosphonic acid, process for their preparation and a pharmaceutical composition
DK8500071 1985-07-25

Publications (3)

Publication Number Publication Date
DK147386D0 true DK147386D0 (da) 1986-04-01
DK147386A DK147386A (da) 1986-04-01
DK167808B1 DK167808B1 (da) 1993-12-20

Family

ID=10564711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK147386A DK167808B1 (da) 1984-07-31 1986-04-01 Methylen-bisphosphonsyrederivat, fremgangsmaade til fremstilling heraf samt farmaceutisk sammensaetning indeholdende disse derivater

Country Status (15)

Country Link
US (1) US4732998A (da)
EP (1) EP0191044B1 (da)
JP (1) JPH068303B2 (da)
KR (1) KR860700254A (da)
AU (1) AU583848B2 (da)
DE (1) DE3575929D1 (da)
DK (1) DK167808B1 (da)
ES (1) ES8707964A1 (da)
FI (1) FI861357A0 (da)
GB (1) GB8419489D0 (da)
GR (1) GR851865B (da)
IE (1) IE58614B1 (da)
PT (1) PT80886B (da)
WO (1) WO1986000902A1 (da)
ZA (1) ZA855264B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3805663A1 (de) * 1988-02-24 1989-09-07 Henkel Kgaa Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5266722A (en) * 1988-11-09 1993-11-30 W. R. Grace & Co.-Conn. Polyether bis-phosphonic acid compounds
PH26923A (en) * 1989-03-08 1992-12-03 Ciba Geigy N-substituted amino alkanediphosphonic acids
FI83421C (fi) * 1989-06-21 1991-07-10 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat.
US5227506A (en) * 1989-09-06 1993-07-13 Merck & Co., Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
EP0416689B1 (en) * 1989-09-06 1995-11-29 Merck & Co. Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
GB9024345D0 (en) * 1990-11-08 1990-12-19 Merck Sharp & Dohme Therapeutic agents
JP3141053B2 (ja) * 1991-12-26 2001-03-05 アベンティス ファーマ株式会社 ビスホスホン酸誘導体
US5200554A (en) * 1992-01-21 1993-04-06 Nasman Jan Anders H Bisphosphonic acid derivatives and their use
EP0603401B1 (en) * 1992-07-10 2001-04-11 Toray Industries, Inc. Methanediphosphonate derivative, production thereof, and pharmaceutical use thereof
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .
US20010007863A1 (en) * 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
AU2002337862A1 (en) * 2001-10-18 2003-04-28 Ilex Products, Inc. Methods of treating skin with diphosphonate derivatives
DE102004032781A1 (de) * 2004-01-23 2005-08-11 Mcs Micro Carrier Systems Gmbh Bisphosphonsäurederivate
JP2006028024A (ja) * 2004-07-12 2006-02-02 Toray Ind Inc リン含有有機化合物の製造方法。
EP2289900A1 (en) * 2009-08-26 2011-03-02 Humboldt Universität zu Berlin Bisphosphonates as inhibitors of acid sphingomyelinase
WO2014008407A1 (en) * 2012-07-05 2014-01-09 University Of Iowa Research Foundation Therapeutic bisphosphonates
WO2017144480A1 (fr) * 2016-02-22 2017-08-31 Surfactis Technologies Compositions a base de composes bisphosphoniques dissous dans un solvant fluore ainsi que leur utilisation pour recouvrir la surface d'une piece

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA777769A (en) * 1963-03-18 1968-02-06 H. Roy Clarence Substituted methylene diphosphonic acid compounds and detergent compositions
US3400131A (en) * 1964-03-05 1968-09-03 Hoffmann La Roche 1, 3-di (4-pyridyl)-2-propanol derivatives
GB1115044A (en) * 1964-08-06 1968-05-22 Albright & Wilson Mfg Ltd Derivatives of hydroxy diphosphonic acids
AT279051B (de) * 1966-12-29 1970-02-25 Procter & Gamble Mundpflegemittel
US3400151A (en) * 1967-12-28 1968-09-03 Procter & Gamble Bicyclic dimer of ethane-1-hydroxy-1, 1-diphosphonic acid and salts thereof
US4014959A (en) 1975-04-24 1977-03-29 Monsanto Company Phosphonoether carboxylates
SU772152A1 (ru) * 1977-07-20 1983-02-15 Центральный научно-исследовательский институт оловянной промышленности 1-Алкоксиалкилиден-1,1-дифосфоновые кислоты или их калиевые,натриевые или аммониевые соли в качестве собирателей дл флотации касситерита и способ их получени
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
ES8707964A1 (es) 1987-09-01
FI861357A7 (fi) 1986-03-27
IE851717L (en) 1986-01-31
AU583848B2 (en) 1989-05-11
EP0191044B1 (en) 1990-02-07
PT80886B (pt) 1987-11-30
FI861357A0 (fi) 1986-03-27
GB8419489D0 (en) 1984-09-05
EP0191044A1 (en) 1986-08-20
GR851865B (da) 1985-12-02
DK147386A (da) 1986-04-01
ES545783A0 (es) 1987-09-01
KR860700254A (ko) 1986-08-01
ZA855264B (en) 1986-03-26
IE58614B1 (en) 1993-10-20
WO1986000902A1 (en) 1986-02-13
DE3575929D1 (de) 1990-03-15
JPH068303B2 (ja) 1994-02-02
US4732998A (en) 1988-03-22
DK167808B1 (da) 1993-12-20
PT80886A (en) 1985-08-01
AU4673685A (en) 1986-02-25
JPS61503034A (ja) 1986-12-25

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Legal Events

Date Code Title Description
PBP Patent lapsed
B1 Patent granted (law 1993)
PBP Patent lapsed