FI861357A0 - Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning. - Google Patents

Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning.

Info

Publication number
FI861357A0
FI861357A0 FI861357A FI861357A FI861357A0 FI 861357 A0 FI861357 A0 FI 861357A0 FI 861357 A FI861357 A FI 861357A FI 861357 A FI861357 A FI 861357A FI 861357 A0 FI861357 A0 FI 861357A0
Authority
FI
Finland
Prior art keywords
methylenbisphosphonsyra
faramceutisk
blandning
derivatives
foerfarande foer
Prior art date
Application number
FI861357A
Other languages
English (en)
Other versions
FI861357A (fi
Inventor
Ernst Torndal Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of FI861357A publication Critical patent/FI861357A/fi
Publication of FI861357A0 publication Critical patent/FI861357A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI861357A 1984-07-31 1986-03-27 Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning. FI861357A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848419489A GB8419489D0 (en) 1984-07-31 1984-07-31 Chemical compounds
PCT/DK1985/000071 WO1986000902A1 (en) 1984-07-31 1985-07-25 Derivatives of methylene-bisphosphonic acid, process for their preparation and a pharmaceutical composition

Publications (2)

Publication Number Publication Date
FI861357A FI861357A (fi) 1986-03-27
FI861357A0 true FI861357A0 (fi) 1986-03-27

Family

ID=10564711

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861357A FI861357A0 (fi) 1984-07-31 1986-03-27 Derivat av metylenbisfosfonsyra, foerfarande foer deras framstaellning och en faramceutisk blandning.

Country Status (15)

Country Link
US (1) US4732998A (fi)
EP (1) EP0191044B1 (fi)
JP (1) JPH068303B2 (fi)
KR (1) KR860700254A (fi)
AU (1) AU583848B2 (fi)
DE (1) DE3575929D1 (fi)
DK (1) DK167808B1 (fi)
ES (1) ES8707964A1 (fi)
FI (1) FI861357A0 (fi)
GB (1) GB8419489D0 (fi)
GR (1) GR851865B (fi)
IE (1) IE58614B1 (fi)
PT (1) PT80886B (fi)
WO (1) WO1986000902A1 (fi)
ZA (1) ZA855264B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3805663A1 (de) * 1988-02-24 1989-09-07 Henkel Kgaa Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5266722A (en) * 1988-11-09 1993-11-30 W. R. Grace & Co.-Conn. Polyether bis-phosphonic acid compounds
PH26923A (en) * 1989-03-08 1992-12-03 Ciba Geigy N-substituted amino alkanediphosphonic acids
FI83421C (fi) * 1989-06-21 1991-07-10 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat.
EP0416689B1 (en) * 1989-09-06 1995-11-29 Merck & Co. Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
US5227506A (en) * 1989-09-06 1993-07-13 Merck & Co., Inc. Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors
GB9024345D0 (en) * 1990-11-08 1990-12-19 Merck Sharp & Dohme Therapeutic agents
JP3141053B2 (ja) * 1991-12-26 2001-03-05 アベンティス ファーマ株式会社 ビスホスホン酸誘導体
US5200554A (en) * 1992-01-21 1993-04-06 Nasman Jan Anders H Bisphosphonic acid derivatives and their use
ES2155446T3 (es) * 1992-07-10 2001-05-16 Toray Industries Derivado de metanodifosfonato, su produccion y su uso farmaceutico.
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .
US20010007863A1 (en) * 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
US6315566B1 (en) 1999-05-18 2001-11-13 3M Innovative Properties Company Dental materials
JP2005511526A (ja) * 2001-10-18 2005-04-28 イレックス プロダクツ インコーポレイテッド ジホスホネート誘導体による皮膚の治療方法
DE102004032781A1 (de) * 2004-01-23 2005-08-11 Mcs Micro Carrier Systems Gmbh Bisphosphonsäurederivate
JP2006028024A (ja) * 2004-07-12 2006-02-02 Toray Ind Inc リン含有有機化合物の製造方法。
EP2289900A1 (en) * 2009-08-26 2011-03-02 Humboldt Universität zu Berlin Bisphosphonates as inhibitors of acid sphingomyelinase
US9745331B2 (en) * 2012-07-05 2017-08-29 University Of Iowa Research Foundation Therapeutic bisphosphonates
CN109312171A (zh) * 2016-02-22 2019-02-05 表面活性剂科技公司 包括溶解在氟化溶剂中的双膦酸根型化合物的组合物及其用于覆盖部件表面的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA777769A (en) * 1963-03-18 1968-02-06 H. Roy Clarence Substituted methylene diphosphonic acid compounds and detergent compositions
US3400131A (en) * 1964-03-05 1968-09-03 Hoffmann La Roche 1, 3-di (4-pyridyl)-2-propanol derivatives
GB1115044A (en) * 1964-08-06 1968-05-22 Albright & Wilson Mfg Ltd Derivatives of hydroxy diphosphonic acids
AT279051B (de) * 1966-12-29 1970-02-25 Procter & Gamble Mundpflegemittel
US3400151A (en) * 1967-12-28 1968-09-03 Procter & Gamble Bicyclic dimer of ethane-1-hydroxy-1, 1-diphosphonic acid and salts thereof
US4014959A (en) * 1975-04-24 1977-03-29 Monsanto Company Phosphonoether carboxylates
SU772152A1 (ru) * 1977-07-20 1983-02-15 Центральный научно-исследовательский институт оловянной промышленности 1-Алкоксиалкилиден-1,1-дифосфоновые кислоты или их калиевые,натриевые или аммониевые соли в качестве собирателей дл флотации касситерита и способ их получени
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
FI861357A (fi) 1986-03-27
ES8707964A1 (es) 1987-09-01
US4732998A (en) 1988-03-22
PT80886A (en) 1985-08-01
DK147386D0 (da) 1986-04-01
DK167808B1 (da) 1993-12-20
IE58614B1 (en) 1993-10-20
KR860700254A (ko) 1986-08-01
GB8419489D0 (en) 1984-09-05
GR851865B (fi) 1985-12-02
AU583848B2 (en) 1989-05-11
PT80886B (pt) 1987-11-30
DK147386A (da) 1986-04-01
IE851717L (en) 1986-01-31
DE3575929D1 (de) 1990-03-15
JPH068303B2 (ja) 1994-02-02
AU4673685A (en) 1986-02-25
EP0191044A1 (en) 1986-08-20
ZA855264B (en) 1986-03-26
JPS61503034A (ja) 1986-12-25
ES545783A0 (es) 1987-09-01
WO1986000902A1 (en) 1986-02-13
EP0191044B1 (en) 1990-02-07

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Legal Events

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Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOEVENS KEMIS