DK538885D0 - Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling herafsamt laegemidler indeholdende disse forbindelser - Google Patents

Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling herafsamt laegemidler indeholdende disse forbindelser

Info

Publication number
DK538885D0
DK538885D0 DK538885A DK538885A DK538885D0 DK 538885 D0 DK538885 D0 DK 538885D0 DK 538885 A DK538885 A DK 538885A DK 538885 A DK538885 A DK 538885A DK 538885 D0 DK538885 D0 DK 538885D0
Authority
DK
Denmark
Prior art keywords
ingrediates
imidazolylkylguanide
procedures
compounds
preparation
Prior art date
Application number
DK538885A
Other languages
English (en)
Other versions
DK165367B (da
DK538885A (da
DK165367C (da
Inventor
A Buschauer
H Schickaneder
W Schunack
S Elz
I Szelenyi
G Baumann
K H Ahrens
Original Assignee
Heumann Pharma Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853512084 external-priority patent/DE3512084A1/de
Priority claimed from DE19853528215 external-priority patent/DE3528215A1/de
Priority claimed from DE19853528214 external-priority patent/DE3528214A1/de
Application filed by Heumann Pharma Gmbh & Co filed Critical Heumann Pharma Gmbh & Co
Publication of DK538885D0 publication Critical patent/DK538885D0/da
Publication of DK538885A publication Critical patent/DK538885A/da
Publication of DK165367B publication Critical patent/DK165367B/da
Application granted granted Critical
Publication of DK165367C publication Critical patent/DK165367C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK538885A 1985-04-02 1985-11-21 Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser DK165367C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19853512084 DE3512084A1 (de) 1985-04-02 1985-04-02 Guanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3512084 1985-04-02
DE19853528215 DE3528215A1 (de) 1985-08-06 1985-08-06 Heteroarylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE19853528214 DE3528214A1 (de) 1985-08-06 1985-08-06 Arylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3528215 1985-08-06
DE3528214 1985-08-06

Publications (4)

Publication Number Publication Date
DK538885D0 true DK538885D0 (da) 1985-11-21
DK538885A DK538885A (da) 1986-10-03
DK165367B DK165367B (da) 1992-11-16
DK165367C DK165367C (da) 1993-04-05

Family

ID=27192965

Family Applications (1)

Application Number Title Priority Date Filing Date
DK538885A DK165367C (da) 1985-04-02 1985-11-21 Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser

Country Status (13)

Country Link
US (1) US5021431A (da)
EP (1) EP0199845B1 (da)
KR (1) KR930011491B1 (da)
AU (1) AU589586B2 (da)
CA (1) CA1266657A (da)
DE (1) DE3579000D1 (da)
DK (1) DK165367C (da)
ES (4) ES8802042A1 (da)
GR (1) GR852852B (da)
HU (1) HU198024B (da)
IE (1) IE58777B1 (da)
PT (1) PT81605B (da)
YU (2) YU45929B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726381A1 (de) * 1987-08-07 1989-02-16 Heumann Pharma Gmbh & Co Guanidincarbonsaeureester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ES2070932T3 (es) * 1990-01-15 1995-06-16 Heumann Pharma Gmbh & Co Derivado de imidazolilpropilguanidina, procedimiento para su preparacion y medicamentos que lo contienen.
ES2058651T3 (es) * 1990-03-30 1994-11-01 Heumann Pharma Gmbh & Co Uso derivados de guanidina para la fabricacion de un medicamento con actividad antagonista de npy.
DE69222757T2 (de) * 1991-02-27 1998-02-12 Seed Capital Investments Imidazol-derivate mit antagonistischer aktivität auf den histamin-h3-receptor
DE4119696A1 (de) * 1991-06-14 1992-12-17 Edmund Dr Neugebauer Verwendung von guanidinderivaten zur herstellung eines arzneimittels zur behandlung des sepsis-syndroms, des sepsis-like syndroms und des septischen schocks
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
US5837716A (en) * 1995-11-13 1998-11-17 Albany Medical College Analgesic heterocyclic compounds
US6127343A (en) * 1996-05-14 2000-10-03 Novo Nordisk A/S Somatostatin agonists and antagonists
ZA974147B (en) * 1996-05-14 1997-11-14 Novo Nordisk As Somatostatin agonists and antagonists.
JP2001502712A (ja) * 1996-10-31 2001-02-27 ノボ ノルディスク アクティーゼルスカブ 束縛されたソマトスタチン・アゴニスト及びアンタゴニスト
DE19755016A1 (de) 1997-12-11 1999-06-17 Bayer Ag Substituierte 2,4-Diamino-1,3,5-triazine
GB9803536D0 (en) 1998-02-19 1998-04-15 Black James Foundation Histamine H,receptor ligands
US6232316B1 (en) 1998-06-16 2001-05-15 Targacept, Inc. Methods for treatment of CNS disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048319A (en) * 1969-10-29 1977-09-13 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with quanidine compounds
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
GB1431589A (en) 1973-07-13 1976-04-07 Smith Kline French Lab Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups
US4062967A (en) * 1974-02-07 1977-12-13 Smith Kline & French Laboratories Limited Bis-guanidino-alkane compounds
US4118496A (en) * 1974-03-12 1978-10-03 Smith Kline & French Laboratories Limited Heterocyclic-methylthioalkyl-amidines
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
GB1602458A (en) * 1977-05-05 1981-11-11 Smith Kline French Lab Bisamidines as histamine h2-antagonists
DK221081A (da) * 1980-05-31 1981-12-01 Smith Kline French Lab Fremgangsmaade til fremstilling af heterocyklylalkylanidiner mellemprodukter til anvendelse ved denne fremgangsmaade og en fremgangsmaade til fremstilling af disse mellemprodukter
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
ES8801821A1 (es) 1988-03-01
PT81605B (pt) 1987-10-20
DK165367B (da) 1992-11-16
HUT41392A (en) 1987-04-28
YU207285A (en) 1988-06-30
AU589586B2 (en) 1989-10-19
ES557693A0 (es) 1988-03-01
ES550875A0 (es) 1988-04-01
YU45469B (en) 1992-05-28
ES557692A0 (es) 1988-03-01
US5021431A (en) 1991-06-04
DK538885A (da) 1986-10-03
HU198024B (en) 1989-07-28
EP0199845B1 (de) 1990-08-01
ES8801819A1 (es) 1988-03-01
DK165367C (da) 1993-04-05
ES557691A0 (es) 1988-03-01
KR930011491B1 (ko) 1993-12-08
GR852852B (da) 1986-08-11
YU45929B (sh) 1992-09-07
KR860008147A (ko) 1986-11-12
IE853319L (en) 1986-10-02
ES8801820A1 (es) 1988-03-01
AU5182886A (en) 1986-10-09
DE3579000D1 (de) 1990-09-06
ES8802042A1 (es) 1988-04-01
CA1266657A (en) 1990-03-13
PT81605A (de) 1986-01-01
EP0199845A1 (de) 1986-11-05
IE58777B1 (en) 1993-11-17
YU210187A (en) 1988-10-31

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