DK431586A - Benzimidazolderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende disse - Google Patents

Benzimidazolderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende disse Download PDF

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Publication number
DK431586A
DK431586A DK431586A DK431586A DK431586A DK 431586 A DK431586 A DK 431586A DK 431586 A DK431586 A DK 431586A DK 431586 A DK431586 A DK 431586A DK 431586 A DK431586 A DK 431586A
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DK
Denmark
Prior art keywords
procedures
preparing
product containing
medicinal product
benzimidazold
Prior art date
Application number
DK431586A
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English (en)
Other versions
DK431586D0 (da
DK170594B1 (da
Inventor
Philippe Manoury
Jean Binet
Gerard Defosse
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK431586D0 publication Critical patent/DK431586D0/da
Publication of DK431586A publication Critical patent/DK431586A/da
Application granted granted Critical
Publication of DK170594B1 publication Critical patent/DK170594B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK431586A 1985-09-11 1986-09-10 Benzimidazol- og imidazoderivater, fremgangsmåde til fremstilling deraf, lægemiddel samt farmaceutisk præparat indeholdende disse DK170594B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8513453A FR2587029B1 (fr) 1985-09-11 1985-09-11 Derives de benzimidazole, leur preparation et leur application en therapeutique
FR8513453 1985-09-11

Publications (3)

Publication Number Publication Date
DK431586D0 DK431586D0 (da) 1986-09-10
DK431586A true DK431586A (da) 1987-03-12
DK170594B1 DK170594B1 (da) 1995-11-06

Family

ID=9322797

Family Applications (1)

Application Number Title Priority Date Filing Date
DK431586A DK170594B1 (da) 1985-09-11 1986-09-10 Benzimidazol- og imidazoderivater, fremgangsmåde til fremstilling deraf, lægemiddel samt farmaceutisk præparat indeholdende disse

Country Status (24)

Country Link
US (2) US4820710A (da)
EP (1) EP0217700B1 (da)
JP (1) JPS6261979A (da)
KR (1) KR930001411B1 (da)
AR (1) AR243187A1 (da)
AT (1) ATE103603T1 (da)
AU (1) AU582894B2 (da)
CA (1) CA1272486A (da)
CS (1) CS357991A3 (da)
DE (2) DE19775081I2 (da)
DK (1) DK170594B1 (da)
ES (1) ES2001782A6 (da)
FI (1) FI87210C (da)
FR (1) FR2587029B1 (da)
GR (1) GR862318B (da)
HU (1) HU196597B (da)
IE (1) IE61607B1 (da)
IL (1) IL79992A (da)
LU (1) LU90085I2 (da)
NL (1) NL970029I2 (da)
NO (2) NO167026C (da)
NZ (1) NZ217537A (da)
PT (1) PT83355B (da)
ZA (1) ZA866901B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618435B1 (fr) * 1987-07-23 1989-10-27 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2637595B1 (fr) * 1988-10-11 1990-11-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
JPH02294758A (ja) * 1989-05-09 1990-12-05 Nec Corp 計算機使用時間管理方式
FR2658823B1 (fr) * 1990-02-27 1992-04-30 Adir Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .
FR2666582B1 (fr) * 1990-09-07 1994-09-02 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique.
FR2693194B1 (fr) * 1992-07-03 1994-09-23 Synthelabo Dérivés d'alcanecarboxamide, leur préparation et leur application thérapeutique.
FR2745500B1 (fr) * 1996-03-04 1998-04-03 Synthelabo Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
JPH10101564A (ja) * 1996-09-27 1998-04-21 Mitsubishi Chem Corp 鼻炎予防及び／又は治療剤
CA2281927C (en) 1997-02-25 2004-01-27 Christopher J. Michejda Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase
FR2762214B1 (fr) * 1997-04-17 2000-10-06 Synthelabo Utilisation de la mizolastine pour la preparation d'un medicament destine au traitement de l'inflammation
EP0958820A1 (en) * 1998-05-19 1999-11-24 Sanofi-Synthelabo Use of an imidazol derivative for the manufacture of a medicament for treating auto-immunodiseases
ES2208098B1 (es) * 2002-10-02 2005-10-16 Ragactives, S.L. Procedimiento e intermedios para la obtencion de derivados de 1-(1h-bencimidazol-2-il)-4-(2-aminopirimidin) piperidina.
HRP20060126A2 (en) * 2003-09-30 2008-05-31 Janssen Pharmaceutica N.V. Benzoimidazole compounds
ES2245227B1 (es) * 2004-04-06 2007-03-01 Ragactives, S.L. Formas cristalinas de mizolastina, procedimientos para su obtencion y composiciones farmaceuticas que las contienen.
WO2010151711A1 (en) * 2009-06-25 2010-12-29 Alkermes, Inc. Prodrugs of nh-acidic compounds
HRP20171415T4 (hr) 2009-06-25 2023-03-03 Alkermes Pharma Ireland Limited Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja
CN102140076A (zh) * 2010-02-03 2011-08-03 辽宁本源制药有限公司 咪唑斯汀中间体的制备
NZ722096A (en) 2011-12-15 2016-11-25 Alkermes Pharma Ireland Ltd Prodrugs of secondary amine compounds
AU2019230014B2 (en) 2018-03-05 2024-11-28 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy
ES3038585T3 (en) * 2019-04-11 2025-10-14 Teijin Pharma Ltd Benzimidazole derivatives and their uses
US12084453B2 (en) 2021-12-10 2024-09-10 Incyte Corporation Bicyclic amines as CDK12 inhibitors
CN116655596A (zh) * 2022-02-17 2023-08-29 济南同路医药科技发展有限公司 一种大粒径咪唑斯汀原料药制备方法
CN120441547A (zh) * 2025-05-06 2025-08-08 大连医科大学附属第二医院 一种新型的脂肪酸酰胺水解酶（faah）抑制剂及其在疾病治疗中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
EP0144101B1 (en) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives

Also Published As

Publication number Publication date
AU582894B2 (en) 1989-04-13
DK431586D0 (da) 1986-09-10
FR2587029B1 (fr) 1987-10-30
NO2001017I1 (no) 2001-11-05
FR2587029A1 (fr) 1987-03-13
IL79992A0 (en) 1986-12-31
PT83355A (fr) 1986-10-01
ES2001782A6 (es) 1988-06-16
CS357991A3 (en) 1992-06-17
DK170594B1 (da) 1995-11-06
KR930001411B1 (ko) 1993-02-27
DE3689748D1 (de) 1994-05-05
KR870003100A (ko) 1987-04-15
NO167026B (no) 1991-06-17
IE61607B1 (en) 1994-11-16
NO863608D0 (no) 1986-09-10
ZA866901B (en) 1987-04-29
DE19775081I2 (de) 2002-08-29
NO863608L (no) 1987-03-12
NZ217537A (en) 1988-11-29
FI863661A0 (fi) 1986-09-10
FI87210C (fi) 1992-12-10
PT83355B (pt) 1989-05-12
JPS6261979A (ja) 1987-03-18
HK1005592A1 (en) 1999-01-15
JPH0460596B2 (da) 1992-09-28
NL970029I1 (nl) 1997-10-01
AR243187A1 (es) 1993-07-30
US4820710A (en) 1989-04-11
GR862318B (en) 1987-01-19
ATE103603T1 (de) 1994-04-15
HUT41771A (en) 1987-05-28
US4912219A (en) 1990-03-27
CA1272486A (en) 1990-08-07
IL79992A (en) 1990-07-12
NL970029I2 (nl) 1998-04-01
IE862416L (en) 1987-03-11
NO167026C (no) 1991-09-25
AU6255286A (en) 1987-03-12
LU90085I2 (fr) 1997-09-25
FI863661L (fi) 1987-03-12
FI87210B (fi) 1992-08-31
HU196597B (en) 1988-12-28
DE3689748T2 (de) 1994-08-11
EP0217700A1 (fr) 1987-04-08
EP0217700B1 (fr) 1994-03-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Free format text: CA 1997 00043, 971031

CTFG Supplementary protection certificate (spc) issued

Free format text: CA 1997 00043, 971031, EXPIRES: 20101121

PUP Patent expired