DK538885A - Imidazolylalkylguanidinderivater, fremgangsmaade til fremstillingheraf samt laegemidler indeholdende disse forbindelser - Google Patents
Imidazolylalkylguanidinderivater, fremgangsmaade til fremstillingheraf samt laegemidler indeholdende disse forbindelser Download PDFInfo
- Publication number
- DK538885A DK538885A DK538885A DK538885A DK538885A DK 538885 A DK538885 A DK 538885A DK 538885 A DK538885 A DK 538885A DK 538885 A DK538885 A DK 538885A DK 538885 A DK538885 A DK 538885A
- Authority
- DK
- Denmark
- Prior art keywords
- ingrediates
- imidazolylalkylguanide
- procedures
- compounds
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3512084 | 1985-04-02 | ||
DE19853512084 DE3512084A1 (de) | 1985-04-02 | 1985-04-02 | Guanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE19853528214 DE3528214A1 (de) | 1985-08-06 | 1985-08-06 | Arylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE19853528215 DE3528215A1 (de) | 1985-08-06 | 1985-08-06 | Heteroarylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3528214 | 1985-08-06 | ||
DE3528215 | 1985-08-06 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK538885D0 DK538885D0 (da) | 1985-11-21 |
DK538885A true DK538885A (da) | 1986-10-03 |
DK165367B DK165367B (da) | 1992-11-16 |
DK165367C DK165367C (da) | 1993-04-05 |
Family
ID=27192965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK538885A DK165367C (da) | 1985-04-02 | 1985-11-21 | Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser |
Country Status (13)
Country | Link |
---|---|
US (1) | US5021431A (da) |
EP (1) | EP0199845B1 (da) |
KR (1) | KR930011491B1 (da) |
AU (1) | AU589586B2 (da) |
CA (1) | CA1266657A (da) |
DE (1) | DE3579000D1 (da) |
DK (1) | DK165367C (da) |
ES (4) | ES8802042A1 (da) |
GR (1) | GR852852B (da) |
HU (1) | HU198024B (da) |
IE (1) | IE58777B1 (da) |
PT (1) | PT81605B (da) |
YU (2) | YU45929B (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3631334A1 (de) * | 1986-09-15 | 1988-03-17 | Heumann Pharma Gmbh & Co | Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3726381A1 (de) * | 1987-08-07 | 1989-02-16 | Heumann Pharma Gmbh & Co | Guanidincarbonsaeureester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ATE120461T1 (de) * | 1990-01-15 | 1995-04-15 | Heumann Pharma Gmbh & Co | Imidazolylpropylguanidinderivat, verfahren zu seiner herstellung und diese verbindung enthaltende arzneimittel. |
ATE109979T1 (de) * | 1990-03-30 | 1994-09-15 | Heumann Pharma Gmbh & Co | Verwendung von guanidinderivaten zur herstellung eines arzneimittels mit npy-antagonistischer wirkung. |
ES2108107T3 (es) * | 1991-02-27 | 1997-12-16 | Seed Capital Investments | Derivados de imidazol que tienen actividad antagonista en el receptor h3 de histamina. |
DE4119696A1 (de) * | 1991-06-14 | 1992-12-17 | Edmund Dr Neugebauer | Verwendung von guanidinderivaten zur herstellung eines arzneimittels zur behandlung des sepsis-syndroms, des sepsis-like syndroms und des septischen schocks |
FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
USRE37303E1 (en) * | 1992-01-10 | 2001-07-31 | Institut National Del La Sante Et De La Recherche Medicale | Imidazole compounds and their therapeutic applications |
CA2237384A1 (en) * | 1995-11-13 | 1997-05-22 | The Albany Medical College | Analgesic compounds and uses thereof |
EP0912551A1 (en) * | 1996-05-14 | 1999-05-06 | Novo Nordisk A/S | Somatostatin agonists and antagonists |
US6127343A (en) * | 1996-05-14 | 2000-10-03 | Novo Nordisk A/S | Somatostatin agonists and antagonists |
AU4772497A (en) * | 1996-10-31 | 1998-05-22 | Novo Nordisk A/S | Constrained somatostatin agonists and antagonists |
DE19755016A1 (de) | 1997-12-11 | 1999-06-17 | Bayer Ag | Substituierte 2,4-Diamino-1,3,5-triazine |
GB9803536D0 (en) | 1998-02-19 | 1998-04-15 | Black James Foundation | Histamine H,receptor ligands |
US6232316B1 (en) | 1998-06-16 | 2001-05-15 | Targacept, Inc. | Methods for treatment of CNS disorders |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE758146A (fr) * | 1969-10-29 | 1971-04-28 | Smith Kline French Lab | Derives de l'amidine |
US4048319A (en) * | 1969-10-29 | 1977-09-13 | Smith Kline & French Laboratories Limited | Method of inhibiting histamine activity with quanidine compounds |
GB1431589A (en) | 1973-07-13 | 1976-04-07 | Smith Kline French Lab | Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups |
US4070472A (en) * | 1974-02-07 | 1978-01-24 | Smith Kline & French Laboratories Limited | Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine |
US4107319A (en) * | 1974-03-12 | 1978-08-15 | Smith Kline & French Laboratories Limited | Pharmacologically active compounds |
IL49528A (en) * | 1975-05-21 | 1980-11-30 | Smith Kline French Lab | Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them |
GB1602458A (en) * | 1977-05-05 | 1981-11-11 | Smith Kline French Lab | Bisamidines as histamine h2-antagonists |
DK221081A (da) * | 1980-05-31 | 1981-12-01 | Smith Kline French Lab | Fremgangsmaade til fremstilling af heterocyklylalkylanidiner mellemprodukter til anvendelse ved denne fremgangsmaade og en fremgangsmaade til fremstilling af disse mellemprodukter |
DE3631334A1 (de) * | 1986-09-15 | 1988-03-17 | Heumann Pharma Gmbh & Co | Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1985
- 1985-11-07 EP EP85114205A patent/EP0199845B1/de not_active Expired - Lifetime
- 1985-11-07 DE DE8585114205T patent/DE3579000D1/de not_active Expired - Fee Related
- 1985-11-20 HU HU854424A patent/HU198024B/hu not_active IP Right Cessation
- 1985-11-21 DK DK538885A patent/DK165367C/da not_active IP Right Cessation
- 1985-11-26 GR GR852852A patent/GR852852B/el unknown
- 1985-12-04 PT PT81605A patent/PT81605B/pt not_active IP Right Cessation
- 1985-12-30 IE IE331985A patent/IE58777B1/en not_active IP Right Cessation
- 1985-12-31 YU YU207285A patent/YU45929B/sh unknown
-
1986
- 1986-01-02 AU AU51828/86A patent/AU589586B2/en not_active Ceased
- 1986-01-07 CA CA000499110A patent/CA1266657A/en not_active Expired - Lifetime
- 1986-01-14 ES ES550875A patent/ES8802042A1/es not_active Expired
- 1986-01-20 KR KR1019860000329A patent/KR930011491B1/ko not_active IP Right Cessation
-
1987
- 1987-08-28 ES ES557692A patent/ES8801820A1/es not_active Expired
- 1987-08-28 ES ES557693A patent/ES8801821A1/es not_active Expired
- 1987-08-28 ES ES557691A patent/ES8801819A1/es not_active Expired
- 1987-11-19 YU YU2101/87A patent/YU45469B/xx unknown
-
1989
- 1989-02-28 US US07/318,467 patent/US5021431A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR930011491B1 (ko) | 1993-12-08 |
ES557692A0 (es) | 1988-03-01 |
AU589586B2 (en) | 1989-10-19 |
ES8802042A1 (es) | 1988-04-01 |
DK538885D0 (da) | 1985-11-21 |
EP0199845B1 (de) | 1990-08-01 |
YU45469B (en) | 1992-05-28 |
HU198024B (en) | 1989-07-28 |
KR860008147A (ko) | 1986-11-12 |
IE853319L (en) | 1986-10-02 |
PT81605B (pt) | 1987-10-20 |
IE58777B1 (en) | 1993-11-17 |
US5021431A (en) | 1991-06-04 |
ES550875A0 (es) | 1988-04-01 |
DE3579000D1 (de) | 1990-09-06 |
GR852852B (da) | 1986-08-11 |
YU45929B (sh) | 1992-09-07 |
ES8801820A1 (es) | 1988-03-01 |
AU5182886A (en) | 1986-10-09 |
ES557693A0 (es) | 1988-03-01 |
DK165367B (da) | 1992-11-16 |
EP0199845A1 (de) | 1986-11-05 |
ES557691A0 (es) | 1988-03-01 |
HUT41392A (en) | 1987-04-28 |
ES8801819A1 (es) | 1988-03-01 |
CA1266657A (en) | 1990-03-13 |
DK165367C (da) | 1993-04-05 |
YU210187A (en) | 1988-10-31 |
ES8801821A1 (es) | 1988-03-01 |
YU207285A (en) | 1988-06-30 |
PT81605A (de) | 1986-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |