DK328187D0 - Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaaden

Info

Publication number
DK328187D0
DK328187D0 DK328187A DK328187A DK328187D0 DK 328187 D0 DK328187 D0 DK 328187D0 DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A DK 328187 D0 DK328187 D0 DK 328187D0
Authority
DK
Denmark
Prior art keywords
procedure
imidazopyridines
intermediates
preparation
Prior art date
Application number
DK328187A
Other languages
English (en)
Other versions
DK169505B1 (da
DK328187A (da
Inventor
Guy Rossey
David Long
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK328187D0 publication Critical patent/DK328187D0/da
Publication of DK328187A publication Critical patent/DK328187A/da
Application granted granted Critical
Publication of DK169505B1 publication Critical patent/DK169505B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
DK328187A 1986-06-27 1987-06-26 Fremgangsmåde til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmåden DK169505B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires
FR8609330 1986-06-27

Publications (3)

Publication Number Publication Date
DK328187D0 true DK328187D0 (da) 1987-06-26
DK328187A DK328187A (da) 1987-12-28
DK169505B1 DK169505B1 (da) 1994-11-14

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK328187A DK169505B1 (da) 1986-06-27 1987-06-26 Fremgangsmåde til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmåden

Country Status (21)

Country Link
US (1) US4794185A (da)
EP (1) EP0251859B1 (da)
JP (1) JPH0653740B2 (da)
KR (1) KR940006594B1 (da)
AR (1) AR243188A1 (da)
AT (1) ATE58537T1 (da)
AU (1) AU7477287A (da)
CA (1) CA1324138C (da)
DE (1) DE3766300D1 (da)
DK (1) DK169505B1 (da)
ES (1) ES2019646B3 (da)
FI (1) FI872850A (da)
FR (1) FR2600650B1 (da)
GR (1) GR3001118T3 (da)
HU (1) HU204826B (da)
IE (1) IE60467B1 (da)
IL (1) IL82982A (da)
NO (1) NO167392C (da)
NZ (1) NZ220853A (da)
PT (1) PT85188B (da)
ZA (1) ZA874643B (da)

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ATE62687T1 (de) * 1986-01-22 1991-05-15 Synthelabo Acylaminomethylimidazo(1,2-a>pyrimidinderivate, ihre herstellung und therapeutische verwendung.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
US6348485B1 (en) 1998-06-09 2002-02-19 Takeda Chemical Industries, Ltd. Method for treating or preventing sleep disorders
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
WO2000058310A1 (en) * 1999-03-25 2000-10-05 Synthon B.V. Zolpidem salts
PT1038875E (pt) 1999-03-25 2003-10-31 Synthon Bv Derivados de imidazopiridina e processo para os preparar
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
EP1272181A2 (en) * 2000-04-13 2003-01-08 Synthon B.V. Modified release formulations containing a hypnotic agent
WO2001080857A1 (en) * 2000-04-24 2001-11-01 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrate
EP1604663A1 (en) * 2000-04-24 2005-12-14 Teva Pharmaceutical Industries Ltd Zolpidem Hemitartrate Form H Solvate
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
AU2000264428A1 (en) * 2000-08-17 2002-02-25 Cilag A.G. Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
CN100408577C (zh) * 2002-07-15 2008-08-06 台湾神隆股份有限公司 咪唑并(1,2-a)吡啶-3-乙酰胺类的制备方法
AU2003297153B2 (en) * 2002-12-18 2010-06-10 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
EP2343073A3 (en) 2003-12-11 2011-10-12 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CA2571491A1 (en) * 2004-06-22 2006-01-19 Mallinckrodt, Inc. Synthesis of heteroaryl acetamides from reaction mixtures having reduced water content
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
CN101277959A (zh) * 2005-10-03 2008-10-01 马林克罗特公司 制备唑吡坦半酒石酸盐和酒石酸盐多晶型的方法
CN101291654A (zh) * 2005-10-17 2008-10-22 马林克罗特公司 片剂基质中唑吡坦的多晶型转化
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
EP1942879A1 (en) 2005-10-31 2008-07-16 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US8148393B2 (en) 2005-11-18 2012-04-03 Synthon Bv Zolpidem tablets
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
BRPI0716604A2 (pt) * 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (da) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NZ220853A (en) 1989-09-27
DE3766300D1 (de) 1991-01-03
US4794185A (en) 1988-12-27
CA1324138C (en) 1993-11-09
PT85188A (fr) 1987-07-01
DK169505B1 (da) 1994-11-14
ES2019646B3 (es) 1991-07-01
FI872850A (fi) 1987-12-28
EP0251859B1 (fr) 1990-11-22
IL82982A0 (en) 1987-12-20
AU7477287A (en) 1988-01-07
NO872682L (no) 1987-12-28
FR2600650A1 (fr) 1987-12-31
DK328187A (da) 1987-12-28
NO167392B (no) 1991-07-22
NO872682D0 (no) 1987-06-26
PT85188B (pt) 1990-03-30
HUT44547A (en) 1988-03-28
KR880000433A (ko) 1988-03-25
HU204826B (en) 1992-02-28
IL82982A (en) 1992-03-29
AR243188A1 (es) 1993-07-30
FI872850A0 (fi) 1987-06-26
JPS638384A (ja) 1988-01-14
NO167392C (no) 1991-10-30
ZA874643B (en) 1988-02-24
KR940006594B1 (ko) 1994-07-23
JPH0653740B2 (ja) 1994-07-20
EP0251859A2 (fr) 1988-01-07
FR2600650B1 (fr) 1988-09-09
IE871723L (en) 1987-12-27
GR3001118T3 (en) 1992-05-12
IE60467B1 (en) 1994-07-13
ATE58537T1 (de) 1990-12-15
EP0251859A3 (en) 1989-07-19

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired