AU582789B2 - Vitamin d derivatives and methods for preparing same - Google Patents
Vitamin d derivatives and methods for preparing sameInfo
- Publication number
- AU582789B2 AU582789B2 AU47761/85A AU4776185A AU582789B2 AU 582789 B2 AU582789 B2 AU 582789B2 AU 47761/85 A AU47761/85 A AU 47761/85A AU 4776185 A AU4776185 A AU 4776185A AU 582789 B2 AU582789 B2 AU 582789B2
- Authority
- AU
- Australia
- Prior art keywords
- vitamin
- gave
- ethyl acetate
- mmol
- hexane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65754984A | 1984-10-04 | 1984-10-04 | |
US657549 | 1984-10-04 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU27614/88A Division AU605007B2 (en) | 1984-10-04 | 1988-12-29 | Steroidal compounds and process for lengthening the side-chain of certain steroids |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4776185A AU4776185A (en) | 1986-04-17 |
AU582789B2 true AU582789B2 (en) | 1989-04-13 |
Family
ID=24637652
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU47761/85A Ceased AU582789B2 (en) | 1984-10-04 | 1985-08-19 | Vitamin d derivatives and methods for preparing same |
AU27614/88A Ceased AU605007B2 (en) | 1984-10-04 | 1988-12-29 | Steroidal compounds and process for lengthening the side-chain of certain steroids |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU27614/88A Ceased AU605007B2 (en) | 1984-10-04 | 1988-12-29 | Steroidal compounds and process for lengthening the side-chain of certain steroids |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0197949A1 (da) |
JP (3) | JPS62500301A (da) |
AU (2) | AU582789B2 (da) |
BE (1) | BE903376A (da) |
CH (1) | CH672920A5 (da) |
DE (2) | DE3590488C2 (da) |
DK (5) | DK154290C (da) |
FR (1) | FR2571369B1 (da) |
GB (2) | GB2167070B (da) |
IE (1) | IE58104B1 (da) |
IT (1) | IT1190401B (da) |
NL (1) | NL8520265A (da) |
WO (1) | WO1986002078A1 (da) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU629831B2 (en) * | 1988-04-29 | 1992-10-15 | Wisconsin Alumni Research Foundation | Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0144358B1 (ko) * | 1988-04-21 | 1998-07-15 | 피. 라이달 크리스텐슨 | 비타민 d 동족체 |
US4927815A (en) * | 1988-04-29 | 1990-05-22 | Wisconsin Alumni Research Foundation | Compounds effective in inducing cell differentiation and process for preparing same |
GB2229921B (en) * | 1989-04-05 | 1992-12-16 | Chugai Pharmaceutical Co Ltd | Treatment for hyperparathyroidism with use of vitamin d derivatives |
DE3933034A1 (de) * | 1989-10-02 | 1991-04-11 | Schering Ag | 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung |
US5030772A (en) * | 1990-02-14 | 1991-07-09 | Deluca Hector F | Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives |
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
US5891865A (en) * | 1996-10-04 | 1999-04-06 | Wisconsin Alumni Research Foundation | Treatment of arthritic disease induced by infectious agents |
WO2006051106A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3880894A (en) * | 1974-05-24 | 1975-04-29 | Wisconsin Alumni Res Found | 1,25-Dihydroxyergocalciferol |
AU2593784A (en) * | 1983-03-21 | 1984-09-27 | F. Hoffmann-La Roche Ag | Pharmaceutical ergocalciferols and intermediates |
AU3011584A (en) * | 1983-05-09 | 1984-12-04 | Wisconsin Alumni Research Foundation | PROCESS FOR THE PREPARATION OF 1a, 25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833622A (en) * | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
AU527805B2 (en) * | 1978-07-27 | 1983-03-24 | Research Institute For Medicine And Chemistry Inc. | 1alpha, 1beta dihydroxy steroid-5-enes |
US4225596A (en) * | 1978-10-13 | 1980-09-30 | Wisconsin Alumni Research Foundation | Method for treating calcium imbalance and improving calcium absorption in mammals |
US4448721A (en) * | 1982-09-20 | 1984-05-15 | Wisconsin Alumni Research Foundation | Hydroxyvitamin D2 compounds and process for preparing same |
-
1985
- 1985-08-19 WO PCT/US1985/001571 patent/WO1986002078A1/en active Application Filing
- 1985-08-19 DE DE3590488A patent/DE3590488C2/de not_active Expired - Lifetime
- 1985-08-19 EP EP85904336A patent/EP0197949A1/en not_active Withdrawn
- 1985-08-19 DE DE19853590488 patent/DE3590488T/de active Pending
- 1985-08-19 JP JP60503924A patent/JPS62500301A/ja active Granted
- 1985-08-19 AU AU47761/85A patent/AU582789B2/en not_active Ceased
- 1985-08-19 CH CH2351/86A patent/CH672920A5/de not_active IP Right Cessation
- 1985-08-19 NL NL8520265A patent/NL8520265A/nl unknown
- 1985-10-04 FR FR8514758A patent/FR2571369B1/fr not_active Expired
- 1985-10-04 GB GB08524479A patent/GB2167070B/en not_active Expired
- 1985-10-04 IE IE244385A patent/IE58104B1/en not_active IP Right Cessation
- 1985-10-04 BE BE0/215682A patent/BE903376A/fr not_active IP Right Cessation
- 1985-10-04 IT IT22359/85A patent/IT1190401B/it active
-
1986
- 1986-06-03 DK DK260086A patent/DK154290C/da active
-
1987
- 1987-04-23 GB GB08709579A patent/GB2188932B/en not_active Expired
-
1988
- 1988-03-02 DK DK111188A patent/DK159389C/da active
- 1988-12-29 AU AU27614/88A patent/AU605007B2/en not_active Ceased
-
1989
- 1989-04-13 DK DK177489A patent/DK158989C/da active
-
1990
- 1990-01-19 DK DK015390A patent/DK158991C/da active
- 1990-01-19 DK DK015290A patent/DK158990C/da active
-
1992
- 1992-05-19 JP JP4150044A patent/JPH0635475B2/ja not_active Expired - Lifetime
- 1992-05-19 JP JP4150045A patent/JPH0689022B2/ja not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3880894A (en) * | 1974-05-24 | 1975-04-29 | Wisconsin Alumni Res Found | 1,25-Dihydroxyergocalciferol |
AU2593784A (en) * | 1983-03-21 | 1984-09-27 | F. Hoffmann-La Roche Ag | Pharmaceutical ergocalciferols and intermediates |
AU3011584A (en) * | 1983-05-09 | 1984-12-04 | Wisconsin Alumni Research Foundation | PROCESS FOR THE PREPARATION OF 1a, 25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU629831B2 (en) * | 1988-04-29 | 1992-10-15 | Wisconsin Alumni Research Foundation | Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia |
Also Published As
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