NL8403588A - Nieuw cefalexinezout, werkwijze ter bereiding daarvan en farmaceutisch preparaat, dat dit bevat. - Google Patents

Nieuw cefalexinezout, werkwijze ter bereiding daarvan en farmaceutisch preparaat, dat dit bevat. Download PDF

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Publication number
NL8403588A
NL8403588A NL8403588A NL8403588A NL8403588A NL 8403588 A NL8403588 A NL 8403588A NL 8403588 A NL8403588 A NL 8403588A NL 8403588 A NL8403588 A NL 8403588A NL 8403588 A NL8403588 A NL 8403588A
Authority
NL
Netherlands
Prior art keywords
cephalexin
monohydrate
crystalline
solvate
hydrochloride
Prior art date
Application number
NL8403588A
Other languages
English (en)
Dutch (nl)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NL8403588A publication Critical patent/NL8403588A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NL8403588A 1983-12-01 1984-11-26 Nieuw cefalexinezout, werkwijze ter bereiding daarvan en farmaceutisch preparaat, dat dit bevat. NL8403588A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/556,887 US4600773A (en) 1983-12-01 1983-12-01 Crystalline cephalexin hydrochloride monohydrate
US55688783 1983-12-01

Publications (1)

Publication Number Publication Date
NL8403588A true NL8403588A (nl) 1985-07-01

Family

ID=24223233

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8403588A NL8403588A (nl) 1983-12-01 1984-11-26 Nieuw cefalexinezout, werkwijze ter bereiding daarvan en farmaceutisch preparaat, dat dit bevat.

Country Status (46)

Country Link
US (1) US4600773A (de)
EP (1) EP0143658B1 (de)
JP (1) JPS60132990A (de)
KR (1) KR870000527B1 (de)
AT (1) AT390616B (de)
AU (1) AU566080B2 (de)
BE (1) BE901142A (de)
BG (1) BG40966A3 (de)
BR (1) BR8406037A (de)
CH (1) CH661732A5 (de)
CS (1) CS248725B2 (de)
CY (1) CY1505A (de)
DD (1) DD229410A5 (de)
DE (1) DE3443065A1 (de)
DK (1) DK158354C (de)
ES (1) ES538019A0 (de)
FI (1) FI80274C (de)
FR (1) FR2555990B1 (de)
GB (1) GB2150566B (de)
GR (1) GR81043B (de)
GT (1) GT198400146A (de)
HK (1) HK92089A (de)
HU (1) HU192516B (de)
IE (1) IE57886B1 (de)
IL (1) IL73639A (de)
IN (1) IN163078B (de)
IT (1) IT1177329B (de)
JO (1) JO1347B1 (de)
LU (1) LU85650A1 (de)
MA (1) MA20279A1 (de)
MX (1) MX159670A (de)
MY (1) MY102966A (de)
NL (1) NL8403588A (de)
NO (1) NO844711L (de)
NZ (1) NZ210357A (de)
OA (1) OA07876A (de)
PH (1) PH20849A (de)
PL (1) PL146014B1 (de)
PT (1) PT79553B (de)
SE (1) SE464026B (de)
SG (1) SG59789G (de)
SU (1) SU1251807A3 (de)
YU (1) YU45680B (de)
ZA (1) ZA849224B (de)
ZM (1) ZM6384A1 (de)
ZW (1) ZW19084A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US5721229A (en) * 1995-12-26 1998-02-24 Veterinary Pharmacy Corporation Soluble forms of cephalosporins and treatment of animals
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
US20040033262A1 (en) * 2002-08-19 2004-02-19 Orchid Health Care Sustained release pharmaceutical composition of a cephalosporin antibiotic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3655656A (en) * 1970-06-04 1972-04-11 Lilly Co Eli Crystalline cephalexin monohydrate
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
US3985747A (en) * 1974-05-24 1976-10-12 Bristol-Myers Company Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
JPS50151890A (de) * 1974-05-30 1975-12-06
CH642850A5 (it) * 1978-10-20 1984-05-15 Ausonia Farma Srl Composizioni farmaceutiche ad attivita antibatterica contro infezioni da germi gram-positivi e gram-negativi.
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device

Also Published As

Publication number Publication date
DK561284A (da) 1985-06-02
AT390616B (de) 1990-06-11
IN163078B (de) 1988-08-06
DK561284D0 (da) 1984-11-27
ZA849224B (en) 1986-07-30
JO1347B1 (en) 1986-11-30
PL146014B1 (en) 1988-12-31
SE8405954L (sv) 1985-06-02
CS248725B2 (en) 1987-02-12
GB2150566A (en) 1985-07-03
FI844631A0 (fi) 1984-11-26
EP0143658A3 (en) 1986-02-12
PT79553A (en) 1984-12-01
IL73639A (en) 1988-06-30
ATA373284A (de) 1989-11-15
US4600773A (en) 1986-07-15
LU85650A1 (fr) 1985-07-17
DE3443065A1 (de) 1985-06-20
ES8602011A1 (es) 1985-11-01
PL250593A1 (en) 1985-07-30
EP0143658A2 (de) 1985-06-05
KR850004765A (ko) 1985-07-27
HUT35685A (en) 1985-07-29
SE464026B (sv) 1991-02-25
FR2555990A1 (fr) 1985-06-07
GT198400146A (es) 1986-05-20
ES538019A0 (es) 1985-11-01
DK158354B (da) 1990-05-07
FR2555990B1 (fr) 1986-12-26
NO844711L (no) 1985-06-03
JPS60132990A (ja) 1985-07-16
GR81043B (en) 1985-03-27
GB8430073D0 (en) 1985-01-09
IE843033L (en) 1985-06-01
NZ210357A (en) 1988-05-30
DD229410A5 (de) 1985-11-06
FI80274B (fi) 1990-01-31
SU1251807A3 (ru) 1986-08-15
CH661732A5 (de) 1987-08-14
JPH0548234B2 (de) 1993-07-20
FI844631L (fi) 1985-06-02
DE3443065C2 (de) 1989-03-23
YU199684A (en) 1987-02-28
FI80274C (fi) 1990-05-10
SE8405954D0 (sv) 1984-11-26
CY1505A (en) 1990-08-03
AU3589784A (en) 1985-06-06
AU566080B2 (en) 1987-10-08
YU45680B (sh) 1992-07-20
MX159670A (es) 1989-08-02
IT8423746A1 (it) 1986-05-27
BG40966A3 (en) 1987-03-14
ZM6384A1 (en) 1985-07-22
MA20279A1 (fr) 1985-07-01
ZW19084A1 (en) 1985-06-12
IL73639A0 (en) 1985-02-28
GB2150566B (en) 1987-08-26
SG59789G (en) 1989-12-29
MY102966A (en) 1993-03-31
BE901142A (fr) 1985-05-28
HU192516B (en) 1987-06-29
DK158354C (da) 1990-10-01
OA07876A (fr) 1986-11-20
EP0143658B1 (de) 1989-03-22
KR870000527B1 (ko) 1987-03-14
HK92089A (en) 1989-11-24
IE57886B1 (en) 1993-05-05
BR8406037A (pt) 1985-08-27
PT79553B (en) 1986-12-15
PH20849A (en) 1987-05-08
IT1177329B (it) 1987-08-26
IT8423746A0 (it) 1984-11-27

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed
BV The patent application has lapsed