ES538019A0 - Un procedimiento para la preparacion de monohidrato de hidrocloruro de cefalexina cristalino - Google Patents

Un procedimiento para la preparacion de monohidrato de hidrocloruro de cefalexina cristalino

Info

Publication number
ES538019A0
ES538019A0 ES538019A ES538019A ES538019A0 ES 538019 A0 ES538019 A0 ES 538019A0 ES 538019 A ES538019 A ES 538019A ES 538019 A ES538019 A ES 538019A ES 538019 A0 ES538019 A0 ES 538019A0
Authority
ES
Spain
Prior art keywords
cephalexine
crystalline
procedure
preparation
hydrochloride monohydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES538019A
Other languages
English (en)
Other versions
ES8602011A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES538019A0 publication Critical patent/ES538019A0/es
Publication of ES8602011A1 publication Critical patent/ES8602011A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES538019A 1983-12-01 1984-11-27 Un procedimiento para la preparacion de monohidrato de hidrocloruro de cefalexina cristalino Expired ES8602011A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/556,887 US4600773A (en) 1983-12-01 1983-12-01 Crystalline cephalexin hydrochloride monohydrate

Publications (2)

Publication Number Publication Date
ES538019A0 true ES538019A0 (es) 1985-11-01
ES8602011A1 ES8602011A1 (es) 1985-11-01

Family

ID=24223233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538019A Expired ES8602011A1 (es) 1983-12-01 1984-11-27 Un procedimiento para la preparacion de monohidrato de hidrocloruro de cefalexina cristalino

Country Status (46)

Country Link
US (1) US4600773A (es)
EP (1) EP0143658B1 (es)
JP (1) JPS60132990A (es)
KR (1) KR870000527B1 (es)
AT (1) AT390616B (es)
AU (1) AU566080B2 (es)
BE (1) BE901142A (es)
BG (1) BG40966A3 (es)
BR (1) BR8406037A (es)
CH (1) CH661732A5 (es)
CS (1) CS248725B2 (es)
CY (1) CY1505A (es)
DD (1) DD229410A5 (es)
DE (1) DE3443065A1 (es)
DK (1) DK158354C (es)
ES (1) ES8602011A1 (es)
FI (1) FI80274C (es)
FR (1) FR2555990B1 (es)
GB (1) GB2150566B (es)
GR (1) GR81043B (es)
GT (1) GT198400146A (es)
HK (1) HK92089A (es)
HU (1) HU192516B (es)
IE (1) IE57886B1 (es)
IL (1) IL73639A (es)
IN (1) IN163078B (es)
IT (1) IT1177329B (es)
JO (1) JO1347B1 (es)
LU (1) LU85650A1 (es)
MA (1) MA20279A1 (es)
MX (1) MX159670A (es)
MY (1) MY102966A (es)
NL (1) NL8403588A (es)
NO (1) NO844711L (es)
NZ (1) NZ210357A (es)
OA (1) OA07876A (es)
PH (1) PH20849A (es)
PL (1) PL146014B1 (es)
PT (1) PT79553B (es)
SE (1) SE464026B (es)
SG (1) SG59789G (es)
SU (1) SU1251807A3 (es)
YU (1) YU45680B (es)
ZA (1) ZA849224B (es)
ZM (1) ZM6384A1 (es)
ZW (1) ZW19084A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US5721229A (en) * 1995-12-26 1998-02-24 Veterinary Pharmacy Corporation Soluble forms of cephalosporins and treatment of animals
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
US20040033262A1 (en) * 2002-08-19 2004-02-19 Orchid Health Care Sustained release pharmaceutical composition of a cephalosporin antibiotic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3655656A (en) * 1970-06-04 1972-04-11 Lilly Co Eli Crystalline cephalexin monohydrate
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
US3985747A (en) * 1974-05-24 1976-10-12 Bristol-Myers Company Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
JPS50151890A (es) * 1974-05-30 1975-12-06
CH642850A5 (it) * 1978-10-20 1984-05-15 Ausonia Farma Srl Composizioni farmaceutiche ad attivita antibatterica contro infezioni da germi gram-positivi e gram-negativi.
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device

Also Published As

Publication number Publication date
DK158354C (da) 1990-10-01
NL8403588A (nl) 1985-07-01
GT198400146A (es) 1986-05-20
YU45680B (sh) 1992-07-20
SE8405954L (sv) 1985-06-02
CY1505A (en) 1990-08-03
BR8406037A (pt) 1985-08-27
FR2555990B1 (fr) 1986-12-26
AU566080B2 (en) 1987-10-08
KR870000527B1 (ko) 1987-03-14
DE3443065A1 (de) 1985-06-20
IN163078B (es) 1988-08-06
IL73639A0 (en) 1985-02-28
DK561284D0 (da) 1984-11-27
GB2150566B (en) 1987-08-26
GR81043B (en) 1985-03-27
PH20849A (en) 1987-05-08
IE843033L (en) 1985-06-01
JPS60132990A (ja) 1985-07-16
HU192516B (en) 1987-06-29
PL250593A1 (en) 1985-07-30
SG59789G (en) 1989-12-29
NO844711L (no) 1985-06-03
FI80274C (fi) 1990-05-10
FI844631L (fi) 1985-06-02
IT8423746A1 (it) 1986-05-27
NZ210357A (en) 1988-05-30
ZM6384A1 (en) 1985-07-22
BE901142A (fr) 1985-05-28
MX159670A (es) 1989-08-02
IT1177329B (it) 1987-08-26
SE8405954D0 (sv) 1984-11-26
JO1347B1 (en) 1986-11-30
CS248725B2 (en) 1987-02-12
OA07876A (fr) 1986-11-20
MA20279A1 (fr) 1985-07-01
ZW19084A1 (en) 1985-06-12
DD229410A5 (de) 1985-11-06
MY102966A (en) 1993-03-31
DK158354B (da) 1990-05-07
PL146014B1 (en) 1988-12-31
FR2555990A1 (fr) 1985-06-07
EP0143658B1 (en) 1989-03-22
DE3443065C2 (es) 1989-03-23
ES8602011A1 (es) 1985-11-01
EP0143658A2 (en) 1985-06-05
PT79553A (en) 1984-12-01
AU3589784A (en) 1985-06-06
KR850004765A (ko) 1985-07-27
PT79553B (en) 1986-12-15
YU199684A (en) 1987-02-28
SU1251807A3 (ru) 1986-08-15
EP0143658A3 (en) 1986-02-12
HK92089A (en) 1989-11-24
IE57886B1 (en) 1993-05-05
IL73639A (en) 1988-06-30
CH661732A5 (de) 1987-08-14
HUT35685A (en) 1985-07-29
AT390616B (de) 1990-06-11
JPH0548234B2 (es) 1993-07-20
IT8423746A0 (it) 1984-11-27
US4600773A (en) 1986-07-15
GB2150566A (en) 1985-07-03
SE464026B (sv) 1991-02-25
LU85650A1 (fr) 1985-07-17
GB8430073D0 (en) 1985-01-09
FI844631A0 (fi) 1984-11-26
DK561284A (da) 1985-06-02
FI80274B (fi) 1990-01-31
ATA373284A (de) 1989-11-15
ZA849224B (en) 1986-07-30
BG40966A3 (en) 1987-03-14

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