NL8005439A - Verbeteringen aan of met betrekking tot een cefalosporine met antibiotische werking. - Google Patents

Verbeteringen aan of met betrekking tot een cefalosporine met antibiotische werking. Download PDF

Info

Publication number
NL8005439A
NL8005439A NL8005439A NL8005439A NL8005439A NL 8005439 A NL8005439 A NL 8005439A NL 8005439 A NL8005439 A NL 8005439A NL 8005439 A NL8005439 A NL 8005439A NL 8005439 A NL8005439 A NL 8005439A
Authority
NL
Netherlands
Prior art keywords
bishydrochloride
crystalline
compound
imino
carboxylate
Prior art date
Application number
NL8005439A
Other languages
English (en)
Dutch (nl)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NL8005439A publication Critical patent/NL8005439A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8005439A 1979-10-02 1980-10-01 Verbeteringen aan of met betrekking tot een cefalosporine met antibiotische werking. NL8005439A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7934203 1979-10-02
GB7934203 1979-10-02

Publications (1)

Publication Number Publication Date
NL8005439A true NL8005439A (nl) 1981-04-06

Family

ID=10508245

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8005439A NL8005439A (nl) 1979-10-02 1980-10-01 Verbeteringen aan of met betrekking tot een cefalosporine met antibiotische werking.

Country Status (14)

Country Link
US (1) US4467086A (xx)
JP (1) JPS5657789A (xx)
AU (1) AU540382B2 (xx)
BE (1) BE885488A (xx)
CH (1) CH644609A5 (xx)
DE (1) DE3037104C2 (xx)
FR (1) FR2466469A1 (xx)
GB (1) GB2064513B (xx)
IE (1) IE50269B1 (xx)
IT (1) IT1128569B (xx)
NL (1) NL8005439A (xx)
NZ (1) NZ195116A (xx)
SE (1) SE449996B (xx)
ZA (1) ZA806082B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963542A (en) * 1976-09-08 1990-10-16 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
IT1145686B (it) * 1979-05-25 1986-11-05 Glaxo Group Ltd Intermedi per la preparazione di antibiotici cefalosporinici e procedimento per prepararli
US4400503A (en) 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
US4394503A (en) 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
US4474954A (en) * 1981-12-07 1984-10-02 Bristol-Myers Company Intermediates for cephalosporin derivatives
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
DE3313816A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4616080A (en) * 1984-07-02 1986-10-07 Eli Lilly And Company Simplified process of forming crystalline ceftazidime pentahydrate
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
AT387022B (de) * 1986-06-04 1988-11-25 Biochemie Gmbh Verfahren zur herstellung einer neuen kristallinen form eines cefalosporinderivats
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
GB8802622D0 (en) * 1988-02-05 1988-03-02 Glaxo Group Ltd Chemical compound
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
IT1145686B (it) * 1979-05-25 1986-11-05 Glaxo Group Ltd Intermedi per la preparazione di antibiotici cefalosporinici e procedimento per prepararli

Also Published As

Publication number Publication date
JPS5657789A (en) 1981-05-20
IE50269B1 (en) 1986-03-19
AU6288080A (en) 1981-04-09
CH644609A5 (de) 1984-08-15
BE885488A (fr) 1981-04-01
JPH0245634B2 (xx) 1990-10-11
NZ195116A (en) 1982-09-07
SE8006860L (sv) 1981-04-03
FR2466469A1 (fr) 1981-04-10
AU540382B2 (en) 1984-11-15
US4467086A (en) 1984-08-21
SE449996B (sv) 1987-06-01
IE802051L (en) 1981-04-02
IT1128569B (it) 1986-05-28
GB2064513A (en) 1981-06-17
ZA806082B (en) 1982-05-26
FR2466469B1 (xx) 1984-02-10
DE3037104C2 (de) 1986-04-30
IT8049782A0 (it) 1980-10-01
DE3037104A1 (de) 1981-04-16
GB2064513B (en) 1983-09-14

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed