NL8001902A - Werkwijze voor het bereiden van dipeptide. - Google Patents

Werkwijze voor het bereiden van dipeptide. Download PDF

Info

Publication number
NL8001902A
NL8001902A NL8001902A NL8001902A NL8001902A NL 8001902 A NL8001902 A NL 8001902A NL 8001902 A NL8001902 A NL 8001902A NL 8001902 A NL8001902 A NL 8001902A NL 8001902 A NL8001902 A NL 8001902A
Authority
NL
Netherlands
Prior art keywords
water
reaction
enzyme
lower alkyl
immobilized enzyme
Prior art date
Application number
NL8001902A
Other languages
English (en)
Dutch (nl)
Original Assignee
Sagami Chem Res
Ajinomoto Kk
Toyo Soda Mfg Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chem Res, Ajinomoto Kk, Toyo Soda Mfg Co Ltd filed Critical Sagami Chem Res
Publication of NL8001902A publication Critical patent/NL8001902A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
NL8001902A 1979-04-03 1980-04-01 Werkwijze voor het bereiden van dipeptide. NL8001902A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4017079 1979-04-03
JP4017079A JPS55135595A (en) 1979-04-03 1979-04-03 Preparation of dipeptide

Publications (1)

Publication Number Publication Date
NL8001902A true NL8001902A (nl) 1980-10-07

Family

ID=12573284

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8001902A NL8001902A (nl) 1979-04-03 1980-04-01 Werkwijze voor het bereiden van dipeptide.

Country Status (10)

Country Link
US (1) US4284721A (fr)
JP (1) JPS55135595A (fr)
BE (1) BE882603A (fr)
CA (1) CA1133841A (fr)
CH (1) CH645341A5 (fr)
DE (1) DE3012693A1 (fr)
FR (1) FR2453137B1 (fr)
GB (1) GB2049703B (fr)
IT (1) IT1147338B (fr)
NL (1) NL8001902A (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52242B1 (en) * 1981-02-02 1987-08-19 Searle & Co Preparation of amino protected-l-aspartyl-l-phenylalanine alkyl ester
US4506011A (en) * 1981-09-05 1985-03-19 Toyo Soda Manufacturing Co., Ltd. Process for preparation of aspartylphenylalanine alkyl esters
DE3361649D1 (en) * 1982-01-26 1986-02-13 Imahori Kazutomo Process for synthesizing peptides or peptide derivatives
US4597308A (en) * 1982-04-19 1986-07-01 Nissan Motor Co., Ltd. Method and apparatus for controlling reduction ratio of continuously variable transmission
JPH0724587B2 (ja) * 1982-07-08 1995-03-22 三井東圧化学株式会社 酵素を利用した反応方法
JPS5917997A (ja) * 1982-07-23 1984-01-30 Toyo Soda Mfg Co Ltd ジペプチドエステルとアミノ酸エステルとの付加化合物の製造方法
DE3479214D1 (en) * 1983-04-28 1989-09-07 Ajinomoto Kk Process for the production of l-aspartyl-l-phenylalanine methyl ester or l-aspartyl-l-phenylalanine
NL8620072A (nl) * 1985-02-15 1986-12-01 Vnii Genetiki Selektsii Promy Werkwijze voor de bereiding van n-formyl-l-peptiden.
NZ217813A (en) * 1985-10-21 1991-01-29 Grace W R & Co Dipeptides and process for their preparation using an enzyme coupling agent
US4810817A (en) * 1985-10-21 1989-03-07 W. R. Grace & Co. Aspartyl-beta substituted phenylalanine dipeptides
US4873359A (en) * 1985-10-21 1989-10-10 W. R. Grace & Co. - Conn. Process for preparing as partyl-phenylalanine dipeptides
FR2589480B1 (fr) * 1985-11-05 1988-09-16 Hoechst France Procede biologique de preparation de n-(n-benzyloxycarbonyl l-aspartyl-1) l-phenylalaninate de methyle
US4935355A (en) * 1986-04-15 1990-06-19 Synthetech, Inc. Preparation of dipeptides
EP0269390B1 (fr) * 1986-11-21 1993-08-25 Genencor International, Inc. Production enzymatique de l'ester alcoylique de L-aspartyl-L-phénylalanine
US4892820A (en) * 1987-06-10 1990-01-09 The Nutrasweet Company Solvent system for enzymatic coupling process
JPH0279993A (ja) * 1987-12-11 1990-03-20 Fan Shun Mou Ii Yuu Shen Kun Tsu Ｌ，ｌ−ジペプチドアスパルテームの製法
EP0344803B1 (fr) * 1988-06-03 1995-09-13 Sharp Kabushiki Kaisha Dispositif électronique avec fonction d'un calendrier
US5002872A (en) * 1989-05-10 1991-03-26 W. R. Grace & Co.-Conn. Enzyme mediated coupling reactions
KR930002966B1 (ko) * 1990-11-24 1993-04-16 주식회사 미 원 디펩티드의 제조방법
DE4408534A1 (de) * 1994-03-14 1995-09-28 Hoechst Ag Substituierte N-Ethyl-Glycinderivate zur Herstellung von PNA und PNA-/DNA-Hybriden
US6465650B1 (en) 1995-03-13 2002-10-15 Aventis Pharma Deutschland Gmbh Substituted N-ethylglycine derivatives for preparing PNA and PNA/DNA hybrids
CA2172022A1 (fr) * 1995-03-20 1996-09-21 Tsugio Murakami Methode pour cristalliser un ester methylique d'alpha-l-aspartyl-l-phenylalanine
EP0768384B1 (fr) * 1995-10-11 2001-06-13 Holland Sweetener Company V.o.F. Réaction améliorée de couplage enzymatique d'acide L-aspartique N-protégé et d'ester méthylique de phenylalanine
DE69613305T2 (de) * 1995-10-11 2002-05-02 Holland Sweetener Co Verbesserte enzymatische Kupplungsreaktion von N-geschützte L-Asparaginsäure und Phenylalaninmethylester
US5837483A (en) * 1996-10-15 1998-11-17 Holland Sweetener Company V.O.F. Enzymatic method for producing N-formyl-α-L-aspartyl-L-phenylalanine methyl ester
BR9815887A (pt) * 1998-06-05 2001-10-23 Wrigley W M Jun Co Método de controle de liberação de derivados de aspartame n-substituìdos em goma de mascar e goma assim produzida
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
CN112301081B (zh) * 2020-10-26 2022-07-22 江南大学 一种酶催化合成苯丙氨酸寡肽-赖氨酸寡肽共聚物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4119493A (en) * 1975-10-23 1978-10-10 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide
US3972773A (en) * 1975-04-29 1976-08-03 Sagami Chemical Research Center Process for producing peptide
DE2801238C2 (de) * 1977-01-27 1986-06-05 (Zaidanhojin) Sagami Chemical Research Center, Tokio/Tokyo Verfahren zur Herstellung von Salzen aus L,L-Dipeptiden und Phenylalaninestern

Also Published As

Publication number Publication date
FR2453137A1 (fr) 1980-10-31
CA1133841A (fr) 1982-10-19
GB2049703A (en) 1980-12-31
DE3012693A1 (de) 1980-10-16
IT1147338B (it) 1986-11-19
GB2049703B (en) 1983-01-12
BE882603A (fr) 1980-10-02
IT8021154A0 (it) 1980-04-02
FR2453137B1 (fr) 1985-06-07
US4284721A (en) 1981-08-18
CH645341A5 (de) 1984-09-28
JPS55135595A (en) 1980-10-22
JPS615399B2 (fr) 1986-02-18
DE3012693C2 (fr) 1990-04-26

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed