NL193266B - Gelyofiliseerde of geprecipiteerde cefalosporine zwitterion en zoutcombinatie. - Google Patents

Gelyofiliseerde of geprecipiteerde cefalosporine zwitterion en zoutcombinatie.

Info

Publication number
NL193266B
NL193266B NL8800025A NL8800025A NL193266B NL 193266 B NL193266 B NL 193266B NL 8800025 A NL8800025 A NL 8800025A NL 8800025 A NL8800025 A NL 8800025A NL 193266 B NL193266 B NL 193266B
Authority
NL
Netherlands
Prior art keywords
lyophilized
precipitated
salt combination
zwitterion
cephalosporin
Prior art date
Application number
NL8800025A
Other languages
English (en)
Other versions
NL193266C (nl
NL8800025A (nl
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NL8800025A publication Critical patent/NL8800025A/nl
Publication of NL193266B publication Critical patent/NL193266B/nl
Application granted granted Critical
Publication of NL193266C publication Critical patent/NL193266C/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
NL8800025A 1987-01-09 1988-01-07 Gelyofiliseerde of geprecipiteerde cefalosporine zwitterion en zoutcombinatie. NL193266C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/001,945 US4808617A (en) 1985-12-18 1987-01-09 Lyophilized or precipitated cephalosporin zwitterion and salt combination
US194587 1987-01-09

Publications (3)

Publication Number Publication Date
NL8800025A NL8800025A (nl) 1988-08-01
NL193266B true NL193266B (nl) 1999-01-04
NL193266C NL193266C (nl) 1999-05-06

Family

ID=21698538

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8800025A NL193266C (nl) 1987-01-09 1988-01-07 Gelyofiliseerde of geprecipiteerde cefalosporine zwitterion en zoutcombinatie.

Country Status (33)

Country Link
US (1) US4808617A (nl)
JP (1) JP2568226B2 (nl)
KR (1) KR950010154B1 (nl)
AR (1) AR243501A1 (nl)
AT (1) AT388672B (nl)
AU (1) AU606361B2 (nl)
BE (1) BE1002114A3 (nl)
CA (1) CA1307464C (nl)
CH (1) CH676202A5 (nl)
CS (1) CS265249B2 (nl)
CY (1) CY1679A (nl)
DD (1) DD264614A5 (nl)
DE (1) DE3740588C2 (nl)
DK (1) DK166404B1 (nl)
ES (1) ES2008951A6 (nl)
FI (1) FI89006C (nl)
FR (1) FR2609396B1 (nl)
GB (1) GB2199746B (nl)
GR (1) GR871860B (nl)
HK (1) HK5593A (nl)
HU (1) HU199686B (nl)
IE (1) IE61238B1 (nl)
IL (1) IL84346A (nl)
IT (1) IT1215666B (nl)
LU (1) LU87102A1 (nl)
NL (1) NL193266C (nl)
OA (1) OA08796A (nl)
PT (1) PT86157B (nl)
SE (1) SE467910B (nl)
SG (1) SG114792G (nl)
SU (1) SU1575942A3 (nl)
YU (1) YU46689B (nl)
ZA (1) ZA88114B (nl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE19539574A1 (de) 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
WO2005094800A2 (en) * 2004-03-31 2005-10-13 Lupin Ltd. A co-precipitated cefepime composition and process for preparation thereof
WO2006109324A2 (en) * 2005-04-13 2006-10-19 Lupin Limited Processes for preparation of amorphous cefepime acid addition salts
JP5491119B2 (ja) * 2009-10-02 2014-05-14 日東電工株式会社 薬物含有微粒子を含む医薬組成物およびその製造方法
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
WO2016035846A1 (ja) 2014-09-04 2016-03-10 塩野義製薬株式会社 カテコール基を有するセファロスポリン類を含有する製剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953439A (en) * 1973-08-01 1976-04-27 Smithkline Corporation Substituted phenylglycylcephalosporins
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
JPS6045514A (ja) * 1983-08-22 1985-03-12 Shionogi & Co Ltd 安定な抗菌性凍結乾燥製剤
US4604386A (en) * 1984-07-09 1986-08-05 Eli Lilly And Company 3-(alkynylalkyloxy) cephalosporins
JPS61130223A (ja) * 1984-11-28 1986-06-18 Shionogi & Co Ltd 抗菌性凍結乾燥製剤
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables

Also Published As

Publication number Publication date
IE61238B1 (en) 1994-10-19
NL193266C (nl) 1999-05-06
LU87102A1 (fr) 1988-08-23
IL84346A0 (en) 1988-04-29
AT388672B (de) 1989-08-10
AU8085687A (en) 1989-05-11
CS15888A2 (en) 1989-01-12
DK577387A (da) 1988-07-10
KR950010154B1 (ko) 1995-09-11
JP2568226B2 (ja) 1996-12-25
ZA88114B (nl) 1988-06-27
KR880008811A (ko) 1988-09-13
IE872970L (en) 1988-07-09
PT86157B (pt) 1991-02-08
DK577387D0 (da) 1987-11-03
PT86157A (en) 1987-12-01
IT8819013A0 (it) 1988-01-07
CA1307464C (en) 1992-09-15
DE3740588A1 (de) 1988-07-21
AR243501A1 (es) 1993-08-31
IT1215666B (it) 1990-02-22
GR871860B (en) 1988-05-10
HK5593A (en) 1993-02-05
JPS63208522A (ja) 1988-08-30
SE467910B (sv) 1992-10-05
CS265249B2 (en) 1989-10-13
ES2008951A6 (es) 1989-08-16
NL8800025A (nl) 1988-08-01
DK166404B1 (da) 1993-05-17
ATA341687A (de) 1989-01-15
YU46689B (sh) 1994-04-05
SG114792G (en) 1992-12-24
DE3740588C2 (de) 1996-07-11
IL84346A (en) 1992-05-25
FI89006C (fi) 1993-08-10
AU606361B2 (en) 1991-02-07
SE8800036L (sv) 1988-07-10
FI875122A0 (fi) 1987-11-19
GB2199746A (en) 1988-07-20
GB8725875D0 (en) 1987-12-09
FR2609396B1 (fr) 1993-01-29
OA08796A (fr) 1989-03-31
HU199686B (en) 1990-03-28
YU2388A (en) 1989-10-31
FR2609396A1 (fr) 1988-07-15
SU1575942A3 (ru) 1990-06-30
SE8800036D0 (sv) 1988-01-08
US4808617A (en) 1989-02-28
GB2199746B (en) 1990-10-24
FI875122A (fi) 1988-07-10
DD264614A5 (de) 1989-02-08
FI89006B (fi) 1993-04-30
HUT46223A (en) 1988-10-28
CH676202A5 (nl) 1990-12-28
BE1002114A3 (fr) 1990-07-10
CY1679A (en) 1993-10-10

Similar Documents

Publication Publication Date Title
BR8900380A (pt) Sistema de suspensao de armacao de poco
DE3887233D1 (de) Hemmung von Mineralabsetzung mit Hilfe von polyanionischen/hydrophobischen Peptiden und deren Derivaten.
DK299087D0 (da) Proteins and derivatives thereof
NO178726C (no) Vandig kalksuspensjon og fremstilling derav
NL193266B (nl) Gelyofiliseerde of geprecipiteerde cefalosporine zwitterion en zoutcombinatie.
DE3676613D1 (de) Gleiskoerper.
NO870126D0 (no) 7-(azabicykloalkyl)-chinolinkarboksylsyre- og naftyri-donkarboksylsyre-derivater.
FI885325A0 (fi) Stabila vaetskeartade system foer framstaellning av spraengaemneskompositioner med hoeg taethet.
DK670689D0 (da) Cephalosporinforbindelser
DK371886A (da) Cephalosporinsalte og injicerbare praeparater
DE3885031D1 (de) Wasserlösliches antibiotisches Präparat und wasserlösliche Salze von Cephem-Verbindungen.
KR890700128A (ko) 세팔로스포린 유도체
DK355888A (da) Peptid samt anvendelsen heraf
DK93586A (da) Cephemforbindelser samt deres fremstilling og anvendelse
NO881502D0 (no) Rekombinante htlv-111 proteiner og anvendelse av disse.
NO885576D0 (no) Trometaminsalt av 1-metyl-beta-okso-alfa-(fenyl-karbamoyl)-2-pyrrolpropionitril.
BR8903477A (pt) Sistema de suspensao
DK200588D0 (da) Thiophenforbindelser samt fremstillingen deraf
DK497088A (da) Vandoploeselige polysakkarider samt fremstilling og anvendelse deraf
DK166385D0 (da) Cephalosporinderivater samt salte deraf
DK503787D0 (da) Cephalosporinderivater
DK688688D0 (da) Cephalosporinderivater samt deres fremstilling og anvendelse
DK529887D0 (da) Ophaengningsorgan
ATE96027T1 (de) Wasserloesliches antibiotisches praeparat und wasserloesliche salze von cephem-verbindungen.
KR880016004U (ko) 인조 마광판

Legal Events

Date Code Title Description
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20080107