MY170889A - Car enzymes and improved production of fatty alcohols - Google Patents

Car enzymes and improved production of fatty alcohols

Info

Publication number
MY170889A
MY170889A MYPI2014002838A MYPI2014002838A MY170889A MY 170889 A MY170889 A MY 170889A MY PI2014002838 A MYPI2014002838 A MY PI2014002838A MY PI2014002838 A MYPI2014002838 A MY PI2014002838A MY 170889 A MY170889 A MY 170889A
Authority
MY
Malaysia
Prior art keywords
fatty alcohols
improved production
enzymes
car
car enzymes
Prior art date
Application number
MYPI2014002838A
Other languages
English (en)
Inventor
Derek L Greenfield
Elizabeth J Clarke
Eli S Groban
Vikranth Arlagadda
Sungwon Lee
Xuezhi Li
Zhihao Hu
Baolong Zhu
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of MY170889A publication Critical patent/MY170889A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0105Long-chain-fatty-acyl-CoA reductase (1.2.1.50)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/99Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with other acceptors (1.2.99)
    • C12Y102/99006Carboxylate reductase (1.2.99.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01041Beta-ketoacyl-acyl-carrier-protein synthase I (2.3.1.41)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/02Thioester hydrolases (3.1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P2203/00Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
MYPI2014002838A 2012-04-02 2013-04-02 Car enzymes and improved production of fatty alcohols MY170889A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261619309P 2012-04-02 2012-04-02

Publications (1)

Publication Number Publication Date
MY170889A true MY170889A (en) 2019-09-12

Family

ID=49237582

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2014002838A MY170889A (en) 2012-04-02 2013-04-02 Car enzymes and improved production of fatty alcohols

Country Status (14)

Country Link
US (4) US9340801B2 (cg-RX-API-DMAC7.html)
EP (6) EP3385374B1 (cg-RX-API-DMAC7.html)
JP (1) JP6230594B2 (cg-RX-API-DMAC7.html)
KR (6) KR101831331B1 (cg-RX-API-DMAC7.html)
CN (1) CN104704113B (cg-RX-API-DMAC7.html)
AU (2) AU2013243602B2 (cg-RX-API-DMAC7.html)
BR (2) BR112014024674B1 (cg-RX-API-DMAC7.html)
CA (1) CA2883064A1 (cg-RX-API-DMAC7.html)
CO (1) CO7170148A2 (cg-RX-API-DMAC7.html)
ES (3) ES2786633T3 (cg-RX-API-DMAC7.html)
MX (2) MX358177B (cg-RX-API-DMAC7.html)
MY (1) MY170889A (cg-RX-API-DMAC7.html)
SI (1) SI3385374T1 (cg-RX-API-DMAC7.html)
WO (1) WO2013152052A2 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2796559B1 (en) * 2008-10-28 2018-09-12 REG Life Sciences, LLC Microbial cell for producing fatty alcohols
MX379251B (es) * 2012-04-02 2025-03-11 Genomatica Inc Producción mejorada de derivados de ácidos grasos.
KR101831331B1 (ko) * 2012-04-02 2018-02-23 알이지 라이프 사이언시스, 엘엘씨 Car 효소들 및 지방족 알코올들의 개선된 생산
WO2014026162A1 (en) 2012-08-10 2014-02-13 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10047383B2 (en) 2013-03-15 2018-08-14 Cargill, Incorporated Bioproduction of chemicals
BR112015023473B1 (pt) * 2013-03-15 2023-04-11 Cargill, Incorporated Microrganismo geneticamente modificado e método de produzir um produto
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
BR112017001105A2 (pt) 2014-07-18 2018-07-24 REG Life Sciences, LLC produção microbiana de dióis graxos
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN105985987B (zh) * 2015-03-02 2020-01-31 苏州安捷生物科技有限公司 一种生物法制备脂肪醇的方法
WO2017161112A1 (en) * 2016-03-17 2017-09-21 Invista Technologies S.A R.L. Carboxylic acid reductase polypeptides and variants having improved activity, materials and processes relating thereto
JP2020506702A (ja) 2017-02-02 2020-03-05 カーギル インコーポレイテッド C6−c10脂肪酸誘導体を生成する遺伝子組み換え細胞
KR102677413B1 (ko) 2017-04-03 2024-06-24 게노마티카 인코포레이티드 중쇄 지방산 유도체의 생산을 위해 개선된 활성을 갖는 티오에스테라제 변이체
EP3844179A4 (en) 2018-08-31 2022-08-31 Genomatica, Inc. XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE
US12221644B2 (en) 2018-08-31 2025-02-11 Genomatica, Inc. Production of non-native monounsaturated fatty acids in bacteria
KR20230160398A (ko) 2021-03-30 2023-11-23 아사히 가세이 가부시키가이샤 카르복실산 환원 활성을 갖는 재조합 폴리펩티드
EP4493683A1 (en) 2022-03-16 2025-01-22 Genomatica, Inc. Acyl-acp thioesterase variants and uses thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5028539A (en) 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
US5482846A (en) 1988-08-31 1996-01-09 University Of Florida Ethanol production in Gram-positive microbes
US5424202A (en) 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
EP0528881A4 (en) 1990-04-24 1993-05-26 Stratagene Methods for phenotype creation from multiple gene populations
US5602030A (en) 1994-03-28 1997-02-11 University Of Florida Research Foundation Recombinant glucose uptake system
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
US5939250A (en) 1995-12-07 1999-08-17 Diversa Corporation Production of enzymes having desired activities by mutagenesis
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US7056714B2 (en) * 2003-03-11 2006-06-06 University Of Iowa Research Foundation, Inc. Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use
DE102004052115A1 (de) 2004-10-26 2006-04-27 Westfälische Wilhelms-Universität Münster Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung
EP2194119A3 (en) 2006-05-19 2010-09-22 LS9, Inc. Production of fatty acids and derivatives thereof
CA2678915C (en) 2007-03-28 2019-04-09 Ls9, Inc. Enhanced production of fatty acid derivatives
CA2679085C (en) 2007-05-22 2018-04-10 Ls9, Inc. Hydrocarbon-producing genes and methods of their use
TWI351779B (en) 2007-12-03 2011-11-01 Advance Smart Ind Ltd Apparatus and method for correcting residual capac
WO2009085278A1 (en) 2007-12-21 2009-07-09 Ls9, Inc. Methods and compositions for producing olefins
CA3038491A1 (en) 2008-10-07 2010-04-15 REG Life Sciences, LLC Bacterial host cells engineered to express a carboxylic acid reductase and a thioesterase
EP2796559B1 (en) * 2008-10-28 2018-09-12 REG Life Sciences, LLC Microbial cell for producing fatty alcohols
US9175234B2 (en) 2008-12-23 2015-11-03 REG Life Sciences, LLC Methods and compositions related to thioesterase enzymes
WO2010127318A2 (en) 2009-05-01 2010-11-04 The Regents Of The University Of California Product of fatty acid esters from biomass polymers
EP2432890B1 (en) * 2009-05-22 2015-09-02 Codexis, Inc. Engineered biosynthesis of fatty alcohols
AU2010306785B2 (en) * 2009-10-13 2016-01-14 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto
WO2011100667A1 (en) 2010-02-14 2011-08-18 Ls9, Inc. Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols
US20110250663A1 (en) 2010-04-08 2011-10-13 Ls9, Inc. Methods and compositions related to fatty alcohol biosynthetic enzymes
EP3702363A1 (en) * 2011-04-01 2020-09-02 Genomatica, Inc. Fadr overexpressing bacterial cells for improved production of fatty acids and derivatives thereof
US9133487B2 (en) * 2011-04-01 2015-09-15 Genomatica, Inc. Microorganisms for producing methacrylic acid and methacrylate esters and methods related thereto
US8617862B2 (en) * 2011-06-22 2013-12-31 Genomatica, Inc. Microorganisms for producing propylene and methods related thereto
KR101831331B1 (ko) * 2012-04-02 2018-02-23 알이지 라이프 사이언시스, 엘엘씨 Car 효소들 및 지방족 알코올들의 개선된 생산

Also Published As

Publication number Publication date
US20160326499A1 (en) 2016-11-10
US20180135028A1 (en) 2018-05-17
US20200109374A1 (en) 2020-04-09
KR20210095226A (ko) 2021-07-30
KR20170113710A (ko) 2017-10-12
AU2013243602B2 (en) 2016-11-24
MX2014011903A (es) 2015-05-12
US20150064757A1 (en) 2015-03-05
EP2834350B1 (en) 2016-11-16
CN104704113B (zh) 2018-01-23
SI3385374T1 (sl) 2020-09-30
EP3674399B1 (en) 2021-09-22
ES2666157T3 (es) 2018-05-03
EP3385374B1 (en) 2020-01-08
EP3674399A1 (en) 2020-07-01
MX358177B (es) 2018-08-08
CO7170148A2 (es) 2015-01-28
JP2015512645A (ja) 2015-04-30
KR102185762B1 (ko) 2020-12-02
BR122019026987B1 (pt) 2022-01-18
BR112014024674B1 (pt) 2022-06-07
KR20200038559A (ko) 2020-04-13
MX343296B (es) 2016-11-01
EP3153579B1 (en) 2018-03-14
EP3985108A1 (en) 2022-04-20
KR20190022935A (ko) 2019-03-06
AU2013243602A1 (en) 2014-11-13
KR20190076059A (ko) 2019-07-01
ES2786633T3 (es) 2020-10-13
AU2016231497A1 (en) 2016-10-06
US10301603B2 (en) 2019-05-28
CA2883064A1 (en) 2013-10-10
BR112014024674A2 (pt) 2018-11-21
EP2834350A2 (en) 2015-02-11
AU2016231497B2 (en) 2017-08-31
KR101831331B1 (ko) 2018-02-23
KR20150032660A (ko) 2015-03-27
WO2013152052A2 (en) 2013-10-10
EP3385374A1 (en) 2018-10-10
ES2613553T3 (es) 2017-05-24
US9340801B2 (en) 2016-05-17
EP3153579A1 (en) 2017-04-12
WO2013152052A3 (en) 2014-03-13
KR102282677B1 (ko) 2021-07-28
US11034937B2 (en) 2021-06-15
EP4186974A1 (en) 2023-05-31
KR102114841B1 (ko) 2020-05-26
CN104704113A (zh) 2015-06-10
US9758769B2 (en) 2017-09-12
JP6230594B2 (ja) 2017-11-15

Similar Documents

Publication Publication Date Title
MY170889A (en) Car enzymes and improved production of fatty alcohols
MY173953A (en) Recombinant host cells for the production of malonate
MX366179B (es) Variantes de enzima con propiedades de ester sintasa mejoradas.
EA201590026A1 (ru) Выработка длинноцепочечных полиненасыщенных жирных кислот в растительных клетках
WO2013152051A3 (en) Improved production of fatty acid derivatives
MX2015009138A (es) Acil-acp reductasa con propiedades mejoradas.
WO2014093505A3 (en) Acp-mediated production of fatty acid derivatives
MX2013004353A (es) Produccion recombinante de n-propanol e isopropanol.
MY176185A (en) Biological methods for preparing a fatty dicarboxylic acid
SG10201607565QA (en) Enzymatic Omega-Oxidation And Omega-Amination Of Fatty Acids
SG11201501013PA (en) Microorganisms and methods for the production of fatty acids and fatty acid derived products
WO2014089268A3 (en) Lgr5+ somatic stem cells
MX2014013329A (es) Variantes de enzimas mejoradas.
IN2015DN02292A (cg-RX-API-DMAC7.html)
PH12015500737A1 (en) Recombinant microorganisms for producing organic acids
IN2014CN02963A (cg-RX-API-DMAC7.html)
IN2014MN01621A (cg-RX-API-DMAC7.html)
EP4223296A3 (en) Nalmefene for reduction of alcohol consumption in specific target populations
IN2014DN02050A (cg-RX-API-DMAC7.html)
EA201691208A1 (ru) Фумаратредуктазы
EP2814972A4 (en) INCREASED PRODUCTION OF FATTY ACIDS AND FATTY ACID DERIVATIVES BY RECOMBINANT MICROORGANISMS
WO2014009685A8 (en) Novel use of alkoxylates of mono- and polyvalent alcohols
AU335314S (en) An upper for footwear
AU341776S (en) An upper for footwear
AU341775S (en) An upper for footwear