MY160607A - Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl) ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same - Google Patents
Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl) ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the sameInfo
- Publication number
- MY160607A MY160607A MYPI2013001148A MYPI2013001148A MY160607A MY 160607 A MY160607 A MY 160607A MY PI2013001148 A MYPI2013001148 A MY PI2013001148A MY PI2013001148 A MYPI2013001148 A MY PI2013001148A MY 160607 A MY160607 A MY 160607A
- Authority
- MY
- Malaysia
- Prior art keywords
- same
- polymorphs
- phenyl
- ethyl
- preparing
- Prior art date
Links
- BVWFJKQJRNSYCR-UHFFFAOYSA-N [4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl] 4-methylbenzoate;hydrochloride Chemical compound Cl.C1CCCCC1(O)C(CN(C)C)C(C=C1)=CC=C1OC(=O)C1=CC=C(C)C=C1 BVWFJKQJRNSYCR-UHFFFAOYSA-N 0.000 title 1
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical compound C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 1
- ACGYSUHUBYZEPP-UHFFFAOYSA-N phenyl 4-methylbenzoate hydrochloride Chemical compound Cl.CC1=CC=C(C(=O)OC2=CC=CC=C2)C=C1 ACGYSUHUBYZEPP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/20—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated the carbon skeleton being saturated and containing rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Gynecology & Obstetrics (AREA)
- Nutrition Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Pregnancy & Childbirth (AREA)
- Psychology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010503737 | 2010-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY160607A true MY160607A (en) | 2017-03-15 |
Family
ID=45891856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2013001148A MY160607A (en) | 2010-10-01 | 2011-09-28 | Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl) ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8741952B2 (https=) |
| EP (1) | EP2621891B1 (https=) |
| JP (7) | JP2014500234A (https=) |
| KR (3) | KR101477154B1 (https=) |
| CN (3) | CN103025705B (https=) |
| AU (1) | AU2011307952B2 (https=) |
| BR (3) | BR122014004636B1 (https=) |
| CA (3) | CA2860747C (https=) |
| CY (1) | CY1122772T1 (https=) |
| DK (1) | DK2621891T3 (https=) |
| ES (1) | ES2769581T3 (https=) |
| MY (1) | MY160607A (https=) |
| PL (1) | PL2621891T3 (https=) |
| PT (1) | PT2621891T (https=) |
| RU (1) | RU2576665C2 (https=) |
| SG (1) | SG188637A1 (https=) |
| WO (1) | WO2012041013A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104672097B (zh) * | 2013-12-03 | 2016-06-29 | 山东绿叶制药有限公司 | 化合物对甲基苯甲酸4-（2-二甲胺基-1-环己烯基乙基）苯酯制备方法及应用 |
| US12346500B1 (en) | 2023-04-17 | 2025-07-01 | Snap Inc. | EMG speech signal detection |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| AU7938798A (en) * | 1997-07-11 | 1999-02-08 | Dainippon Pharmaceutical Co. Ltd. | (r)-n-(1-ethyl-1h-hexahydroazepin-3-yl)-6-methoxy-1h-benzotr azole-5-carboxamidemonofumarate monohydrate and process for producing the same |
| DE60039132D1 (de) * | 1999-04-06 | 2008-07-17 | Sepracor Inc | O-Desmethylvenlafaxin-Succinat |
| US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| US7291646B2 (en) | 1999-11-24 | 2007-11-06 | Wyeth | Ethers of O-desmethyl venlafaxine |
| EP1232141B1 (en) * | 1999-11-24 | 2004-10-06 | Wyeth | Ethers of o-desmethyl venlafaxine |
| US6348494B1 (en) * | 2000-11-21 | 2002-02-19 | American Home Products Corporation | Ethers of o-desmethyl venlafaxine |
| SK5762003A3 (en) * | 2000-10-19 | 2003-11-04 | Teva Pharma | Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof |
| AU2001235970A1 (en) * | 2000-12-07 | 2002-06-18 | Dr. Reddy's Research Foundation | Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation |
| EP1864967A1 (en) | 2001-02-12 | 2007-12-12 | Wyeth | Method for preparing O-desmethyl-venlafaxine |
| US20040242594A1 (en) * | 2001-11-17 | 2004-12-02 | Dan Peters | Prodrugs of antidepressants and their use for treating depressions |
| CN1630631A (zh) | 2001-12-05 | 2005-06-22 | 惠氏公司 | 新的文拉法星盐酸盐多晶型物及其制备方法 |
| US20030190352A1 (en) | 2002-03-28 | 2003-10-09 | Synthon Bv | Compositions of venlafaxine base |
| US20030195170A1 (en) * | 2002-04-11 | 2003-10-16 | Judith Aronhime | Novel polymorphs and pseudopolymorphs of risedronate sodium |
| US7875642B2 (en) * | 2004-01-26 | 2011-01-25 | Merck Sharp & Dohme Corp. | Crystalline forms of an inhibitor of 11-β-hydroxysteroid dehydrogenase type 1 |
| CN100455560C (zh) * | 2004-06-09 | 2009-01-28 | 中国人民解放军军事医学科学院放射医学研究所 | 含长链脂肪酰基取代的文拉法辛前体药物及其制备方法和用途 |
| CN1955159B (zh) * | 2005-06-17 | 2010-11-24 | 山东绿叶制药有限公司 | 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途 |
| GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales |
-
2011
- 2011-09-28 SG SG2013021472A patent/SG188637A1/en unknown
- 2011-09-28 BR BR122014004636-7A patent/BR122014004636B1/pt active IP Right Grant
- 2011-09-28 CA CA2860747A patent/CA2860747C/en active Active
- 2011-09-28 PL PL11827911T patent/PL2621891T3/pl unknown
- 2011-09-28 BR BR122014004640-5A patent/BR122014004640B1/pt active IP Right Grant
- 2011-09-28 KR KR1020147007371A patent/KR101477154B1/ko active Active
- 2011-09-28 AU AU2011307952A patent/AU2011307952B2/en active Active
- 2011-09-28 ES ES11827911T patent/ES2769581T3/es active Active
- 2011-09-28 CN CN201180036015.8A patent/CN103025705B/zh active Active
- 2011-09-28 KR KR1020147007372A patent/KR101477155B1/ko active Active
- 2011-09-28 CA CA2812227A patent/CA2812227C/en active Active
- 2011-09-28 BR BR112013008664-5A patent/BR112013008664B1/pt active IP Right Grant
- 2011-09-28 EP EP11827911.6A patent/EP2621891B1/en active Active
- 2011-09-28 JP JP2013530528A patent/JP2014500234A/ja active Pending
- 2011-09-28 CA CA2860748A patent/CA2860748C/en active Active
- 2011-09-28 RU RU2013119806/04A patent/RU2576665C2/ru active
- 2011-09-28 PT PT118279116T patent/PT2621891T/pt unknown
- 2011-09-28 CN CN201310464696.9A patent/CN103588653B/zh active Active
- 2011-09-28 DK DK11827911.6T patent/DK2621891T3/da active
- 2011-09-28 CN CN201310462622.1A patent/CN103588652B/zh active Active
- 2011-09-28 MY MYPI2013001148A patent/MY160607A/en unknown
- 2011-09-28 KR KR1020137011253A patent/KR101640808B1/ko active Active
- 2011-09-28 WO PCT/CN2011/001637 patent/WO2012041013A1/en not_active Ceased
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2013
- 2013-03-18 US US13/846,773 patent/US8741952B2/en active Active
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2014
- 2014-04-23 US US14/259,964 patent/US9199912B2/en active Active
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2015
- 2015-08-07 JP JP2015156966A patent/JP2015205932A/ja active Pending
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2016
- 2016-06-23 JP JP2016124043A patent/JP2016188233A/ja active Pending
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2017
- 2017-09-08 JP JP2017172806A patent/JP6434591B2/ja active Active
- 2017-09-08 JP JP2017172815A patent/JP2017210494A/ja active Pending
- 2017-12-14 JP JP2017239299A patent/JP6522094B2/ja active Active
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2019
- 2019-07-19 JP JP2019133324A patent/JP6908657B2/ja active Active
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2020
- 2020-02-03 CY CY20201100094T patent/CY1122772T1/el unknown
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