CN103025705B - 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 - Google Patents
4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 Download PDFInfo
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- BOKRJZJUBWPCJZ-BRPDVVIDSA-N CC/N=C(/C)\CC(C1(CCCCC1)O)c(cc1)ccc1[O](C)(C1C=CC(C2[IH]C2)=CC1)=O Chemical compound CC/N=C(/C)\CC(C1(CCCCC1)O)c(cc1)ccc1[O](C)(C1C=CC(C2[IH]C2)=CC1)=O BOKRJZJUBWPCJZ-BRPDVVIDSA-N 0.000 description 1
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- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201180036015.8A CN103025705B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010503737 | 2010-10-01 | ||
| CN201010503737.7 | 2010-10-01 | ||
| PCT/CN2011/001637 WO2012041013A1 (en) | 2010-10-01 | 2011-09-28 | Polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same |
| CN201180036015.8A CN103025705B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310464696.9A Division CN103588653B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
| CN201310462622.1A Division CN103588652B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103025705A CN103025705A (zh) | 2013-04-03 |
| CN103025705B true CN103025705B (zh) | 2014-01-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201180036015.8A Active CN103025705B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
| CN201310464696.9A Active CN103588653B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
| CN201310462622.1A Active CN103588652B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310464696.9A Active CN103588653B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
| CN201310462622.1A Active CN103588652B (zh) | 2010-10-01 | 2011-09-28 | 4-甲基苯甲酸4-[2-二甲基胺基-1-(1-羟基环己基)乙基]苯酯盐酸盐的多晶型物、制备方法及其应用 |
Country Status (17)
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|---|---|
| US (2) | US8741952B2 (https=) |
| EP (1) | EP2621891B1 (https=) |
| JP (7) | JP2014500234A (https=) |
| KR (3) | KR101477154B1 (https=) |
| CN (3) | CN103025705B (https=) |
| AU (1) | AU2011307952B2 (https=) |
| BR (3) | BR122014004636B1 (https=) |
| CA (3) | CA2860747C (https=) |
| CY (1) | CY1122772T1 (https=) |
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| MY (1) | MY160607A (https=) |
| PL (1) | PL2621891T3 (https=) |
| PT (1) | PT2621891T (https=) |
| RU (1) | RU2576665C2 (https=) |
| SG (1) | SG188637A1 (https=) |
| WO (1) | WO2012041013A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104672097B (zh) * | 2013-12-03 | 2016-06-29 | 山东绿叶制药有限公司 | 化合物对甲基苯甲酸4-(2-二甲胺基-1-环己烯基乙基)苯酯制备方法及应用 |
| US12346500B1 (en) | 2023-04-17 | 2025-07-01 | Snap Inc. | EMG speech signal detection |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050197392A1 (en) * | 1999-04-06 | 2005-09-08 | Sepracor Inc. | O-desmethylvenlafaxine and methods of preparing and using the same |
| AU2006257558A1 (en) * | 2005-06-17 | 2006-12-21 | Li, Youxin | Compounds for inhibition of 5-hydroxytryptamine and norepinephrine reuptake or for treatment of depression disorders, their preparation processes and uses thereof |
| CN100455560C (zh) * | 2004-06-09 | 2009-01-28 | 中国人民解放军军事医学科学院放射医学研究所 | 含长链脂肪酰基取代的文拉法辛前体药物及其制备方法和用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535186A (en) | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| AU7938798A (en) * | 1997-07-11 | 1999-02-08 | Dainippon Pharmaceutical Co. Ltd. | (r)-n-(1-ethyl-1h-hexahydroazepin-3-yl)-6-methoxy-1h-benzotr azole-5-carboxamidemonofumarate monohydrate and process for producing the same |
| US20020022662A1 (en) | 1999-06-15 | 2002-02-21 | American Home Products Corporation | Enantiomers of O-desmethyl venlafaxine |
| US7291646B2 (en) | 1999-11-24 | 2007-11-06 | Wyeth | Ethers of O-desmethyl venlafaxine |
| EP1232141B1 (en) * | 1999-11-24 | 2004-10-06 | Wyeth | Ethers of o-desmethyl venlafaxine |
| US6348494B1 (en) * | 2000-11-21 | 2002-02-19 | American Home Products Corporation | Ethers of o-desmethyl venlafaxine |
| SK5762003A3 (en) * | 2000-10-19 | 2003-11-04 | Teva Pharma | Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof |
| AU2001235970A1 (en) * | 2000-12-07 | 2002-06-18 | Dr. Reddy's Research Foundation | Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation |
| EP1864967A1 (en) | 2001-02-12 | 2007-12-12 | Wyeth | Method for preparing O-desmethyl-venlafaxine |
| US20040242594A1 (en) * | 2001-11-17 | 2004-12-02 | Dan Peters | Prodrugs of antidepressants and their use for treating depressions |
| CN1630631A (zh) | 2001-12-05 | 2005-06-22 | 惠氏公司 | 新的文拉法星盐酸盐多晶型物及其制备方法 |
| US20030190352A1 (en) | 2002-03-28 | 2003-10-09 | Synthon Bv | Compositions of venlafaxine base |
| US20030195170A1 (en) * | 2002-04-11 | 2003-10-16 | Judith Aronhime | Novel polymorphs and pseudopolymorphs of risedronate sodium |
| US7875642B2 (en) * | 2004-01-26 | 2011-01-25 | Merck Sharp & Dohme Corp. | Crystalline forms of an inhibitor of 11-β-hydroxysteroid dehydrogenase type 1 |
| GT200600397A (es) * | 2005-09-07 | 2007-08-28 | Formulas topicas conteniendo o-desmetil venlafaxina (odv) o sus sales |
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