MY147795A - Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes - Google Patents

Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes

Info

Publication number
MY147795A
MY147795A MYPI20063479A MYPI20063479A MY147795A MY 147795 A MY147795 A MY 147795A MY PI20063479 A MYPI20063479 A MY PI20063479A MY PI20063479 A MYPI20063479 A MY PI20063479A MY 147795 A MY147795 A MY 147795A
Authority
MY
Malaysia
Prior art keywords
oxo
carbolactones
dihydroxyandrostanes
pregn
ene
Prior art date
Application number
MYPI20063479A
Other languages
English (en)
Inventor
Seilz Carsten
Seba Hartmut
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35744678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY147795(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of MY147795A publication Critical patent/MY147795A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MYPI20063479A 2005-07-21 2006-07-20 Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes MY147795A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05090214.7A EP1746101B2 (de) 2005-07-21 2005-07-21 Verfahren zur Herstellung von 3-Oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie Oxidation von 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanen

Publications (1)

Publication Number Publication Date
MY147795A true MY147795A (en) 2013-01-31

Family

ID=35744678

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20063479A MY147795A (en) 2005-07-21 2006-07-20 Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes

Country Status (22)

Country Link
US (2) US20070049747A1 (https=)
EP (1) EP1746101B2 (https=)
JP (2) JP5345843B2 (https=)
CN (1) CN101223186B (https=)
AR (1) AR055993A1 (https=)
AT (1) ATE403668T1 (https=)
CY (1) CY1110411T1 (https=)
DE (1) DE502005004948D1 (https=)
DK (1) DK1746101T4 (https=)
DO (1) DOP2006000172A (https=)
ES (1) ES2311927T5 (https=)
GT (1) GT200600321A (https=)
MY (1) MY147795A (https=)
PE (2) PE20131303A1 (https=)
PL (1) PL1746101T5 (https=)
PT (1) PT1746101E (https=)
SI (1) SI1746101T2 (https=)
SV (1) SV2007002621A (https=)
TW (1) TWI392683B (https=)
UA (1) UA100092C2 (https=)
UY (1) UY29686A1 (https=)
ZA (1) ZA200801674B (https=)

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PT1746101E (pt) * 2005-07-21 2008-10-27 Bayer Schering Pharma Ag Processo para o fabrico de 3-oxo-pregn-4-eno-21,17-carbolactonas por meio de oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-di-hidroxiandrostanos
WO2009111574A2 (en) * 2008-03-05 2009-09-11 Evestra, Inc. BISMETHYLENE-17α CARBOLACTONES AND RELATED USES
DE102008026793A1 (de) * 2008-06-02 2009-12-03 Bayer Schering Pharma Aktiengesellschaft C-Ring-substituierte Pregn-4-en-21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
US8222237B2 (en) * 2008-11-25 2012-07-17 Evestra, Inc. Progestational 3-(6,6-ethylene-17B-hydroxy-3-oxo-17A-pregna-4-ene-17A-yl)propionic acid G-lactones
US8334375B2 (en) * 2009-04-10 2012-12-18 Evestra, Inc. Methods for the preparation of drospirenone
EP2266998B1 (en) 2009-06-16 2013-07-24 Crystal Pharma, S.A.U. Process for obtaining 17-spirolactones in steroids
CN101775057B (zh) * 2010-02-09 2014-07-16 浙江仙琚制药股份有限公司 屈螺酮及其中间体的制备方法
CN101830959B (zh) * 2010-05-27 2012-07-18 杭州龙山化工有限公司 一种曲螺酮的合成方法
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
WO2012107513A1 (en) 2011-02-10 2012-08-16 Crystal Pharma, S.A.U. Process for obtaining drospirenone
CN102746370A (zh) * 2011-04-22 2012-10-24 天津金耀集团有限公司 一种氧化合成孕甾11位酮基的新工艺
KR101672109B1 (ko) * 2012-01-13 2016-11-02 쌩-고벵 글래스 프랑스 단열 창유리 유닛용 스페이서
CN102887934B (zh) * 2012-09-20 2015-05-27 杭州福斯特药业有限公司 一种屈螺酮的制备方法
JP6469078B2 (ja) * 2013-04-12 2019-02-13 インドゥスティアーレ キーミカ エッセ．エッレ．エッレ． ドロスピレノン調製のためのプロセス
CN104163846A (zh) * 2013-05-17 2014-11-26 上海创诺制药有限公司 一种制备曲螺酮的方法
WO2015086457A2 (de) 2013-12-12 2015-06-18 Saint-Gobain Glass France Isolierverglasung mit verbesserter abdichtung
EP3080376A1 (de) 2013-12-12 2016-10-19 Saint-Gobain Glass France Abstandshalter für isolierverglasungen mit extrudiertem dichtprofil
CN104788524B (zh) * 2014-01-16 2016-07-06 浙江仙居君业药业有限公司 一种19-去甲-4-雄甾烯-3,17-二酮的制备方法
US10301868B2 (en) 2014-06-27 2019-05-28 Saint-Gobain Glass France Insulated glazing comprising a spacer, and production method
US10344525B2 (en) 2014-06-27 2019-07-09 Saint-Gobain Glass France Insulated glazing with spacer, related methods and uses
MX374373B (es) 2014-09-25 2025-03-06 Saint Gobain Separador para unidades de acristalamiento aislantes.
DK3265636T3 (da) 2015-03-02 2022-05-23 Saint Gobain Glasfiberforstærket afstandsholder til isoleringsrude, fremgangsmåde til fremstilling af denne og anvendelse af en sådan afstandsholder i flerlagsruder
CA2989975C (en) 2015-06-23 2021-10-12 Laboratorios Leon Farma Sa Drospirenone-based contraceptive for a female patient affected with excess weight
EP3108889A1 (en) 2015-06-23 2016-12-28 Philippe Perrin Drospirenone-based contraceptive for a female patient affected with excess weight

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
US4069219A (en) 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
DE3026783C2 (de) 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
DE3042136A1 (de) 1980-11-03 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden
EP0075189B1 (en) 1981-09-21 1985-08-28 Schering Aktiengesellschaft 3-beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation
US5106995A (en) 1989-05-05 1992-04-21 Isp Investments Inc. Production of lactones from diols
DE3916112A1 (de) * 1989-05-16 1990-11-22 Schering Ag Dihydrospirorenon als antiandrogen
DE19633685C1 (de) * 1996-08-12 1997-10-09 Schering Ag Verfahren zur Herstellung von Drospirenon (6beta,7beta;15 beta,16beta-Dimethyl-en-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, DRSP) sowie 7alpha-(3-Hydroxy-1-propyl)-6beta,7beta;15beta, 16beta-dimethylen-5beta-androstan-3beta,5,17beta-triol (ZK 92836) und 6beta,7beta;15beta,16beta-dimethylen-5beta-hydroxy-3-oxo-17alpha-androstan-21,17-carbolacton (90965) als Zwischenprodukte des Verfahrens
JP2006507369A (ja) * 2002-08-16 2006-03-02 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ５−アンドロステン−３β−オールステロイド中間体およびそれらの製法
JP2005027184A (ja) * 2003-07-04 2005-01-27 Seiko Epson Corp 高周波複合部品
ITMI20040367A1 (it) 2004-03-01 2004-06-01 Ind Chimica Srl Processo per la preparazione di drospirenone
ITMI20042338A1 (it) * 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone
US7319154B2 (en) * 2005-07-21 2008-01-15 Bayer Schering Pharma Ag Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes
PT1746101E (pt) * 2005-07-21 2008-10-27 Bayer Schering Pharma Ag Processo para o fabrico de 3-oxo-pregn-4-eno-21,17-carbolactonas por meio de oxidação isenta de metais de 17-(3-hidroxipropil)-3,17-di-hidroxiandrostanos
US20080032147A1 (en) * 2005-08-26 2008-02-07 Thomas Neel Medium density fibreboard

Also Published As

Publication number Publication date
JP2013177450A (ja) 2013-09-09
EP1746101B1 (de) 2008-08-06
SI1746101T2 (sl) 2014-09-30
UY29686A1 (es) 2007-02-28
CY1110411T1 (el) 2015-04-29
PE20131303A1 (es) 2013-11-27
TW200716660A (en) 2007-05-01
CN101223186B (zh) 2012-09-05
PL1746101T3 (pl) 2009-01-30
JP5345843B2 (ja) 2013-11-20
PE20070215A1 (es) 2007-04-11
DK1746101T3 (da) 2008-11-24
EP1746101A1 (de) 2007-01-24
JP2009501753A (ja) 2009-01-22
ES2311927T5 (es) 2014-09-08
EP1746101B2 (de) 2014-05-14
SI1746101T1 (sl) 2009-02-28
US8658788B2 (en) 2014-02-25
PT1746101E (pt) 2008-10-27
ZA200801674B (en) 2009-08-26
ATE403668T1 (de) 2008-08-15
CN101223186A (zh) 2008-07-16
TWI392683B (zh) 2013-04-11
SV2007002621A (es) 2007-12-12
DOP2006000172A (es) 2007-02-15
PL1746101T5 (pl) 2014-11-28
ES2311927T3 (es) 2009-02-16
DE502005004948D1 (de) 2008-09-18
UA100092C2 (en) 2012-11-12
AR055993A1 (es) 2007-09-12
DK1746101T4 (da) 2014-08-11
US20110275796A1 (en) 2011-11-10
GT200600321A (es) 2007-02-23
US20070049747A1 (en) 2007-03-01

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