DK1746101T4 - Fremgangsmåde til fremstilling af 3-oxo-pregn-4-en-21,17-carbolactoner ved metalfri oxidation af 17-(3-hydroxypropyl)-3,17-dihydroxyandrostaner - Google Patents

Fremgangsmåde til fremstilling af 3-oxo-pregn-4-en-21,17-carbolactoner ved metalfri oxidation af 17-(3-hydroxypropyl)-3,17-dihydroxyandrostaner

Info

Publication number
DK1746101T4
DK1746101T4 DK05090214.7T DK05090214T DK1746101T4 DK 1746101 T4 DK1746101 T4 DK 1746101T4 DK 05090214 T DK05090214 T DK 05090214T DK 1746101 T4 DK1746101 T4 DK 1746101T4
Authority
DK
Denmark
Prior art keywords
dihydroxyandrostanes
carbolactones
pregn
ene
oxo
Prior art date
Application number
DK05090214.7T
Other languages
English (en)
Other versions
DK1746101T3 (da
Inventor
Carsten Seilz
Hartmut Seba
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35744678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1746101(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of DK1746101T3 publication Critical patent/DK1746101T3/da
Application granted granted Critical
Publication of DK1746101T4 publication Critical patent/DK1746101T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
DK05090214.7T 2005-07-21 2005-07-21 Fremgangsmåde til fremstilling af 3-oxo-pregn-4-en-21,17-carbolactoner ved metalfri oxidation af 17-(3-hydroxypropyl)-3,17-dihydroxyandrostaner DK1746101T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05090214.7A EP1746101B2 (de) 2005-07-21 2005-07-21 Verfahren zur Herstellung von 3-Oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie Oxidation von 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanen

Publications (2)

Publication Number Publication Date
DK1746101T3 DK1746101T3 (da) 2008-11-24
DK1746101T4 true DK1746101T4 (da) 2014-08-11

Family

ID=35744678

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05090214.7T DK1746101T4 (da) 2005-07-21 2005-07-21 Fremgangsmåde til fremstilling af 3-oxo-pregn-4-en-21,17-carbolactoner ved metalfri oxidation af 17-(3-hydroxypropyl)-3,17-dihydroxyandrostaner

Country Status (22)

Country Link
US (2) US20070049747A1 (da)
EP (1) EP1746101B2 (da)
JP (2) JP5345843B2 (da)
CN (1) CN101223186B (da)
AR (1) AR055993A1 (da)
AT (1) ATE403668T1 (da)
CY (1) CY1110411T1 (da)
DE (1) DE502005004948D1 (da)
DK (1) DK1746101T4 (da)
DO (1) DOP2006000172A (da)
ES (1) ES2311927T5 (da)
GT (1) GT200600321A (da)
MY (1) MY147795A (da)
PE (2) PE20070215A1 (da)
PL (1) PL1746101T5 (da)
PT (1) PT1746101E (da)
SI (1) SI1746101T2 (da)
SV (1) SV2007002621A (da)
TW (1) TWI392683B (da)
UA (1) UA100092C2 (da)
UY (1) UY29686A1 (da)
ZA (1) ZA200801674B (da)

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ATE403668T1 (de) * 2005-07-21 2008-08-15 Bayer Schering Pharma Ag Verfahren zur herstellung von 3-oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie oxidation von 17-(3-hydroxypropyl)-3,17- dihydroxyandrostanen
US7960368B2 (en) * 2008-03-05 2011-06-14 Everstra, Inc. Bismethylene-17A carbolactones and related uses
DE102008026793A1 (de) * 2008-06-02 2009-12-03 Bayer Schering Pharma Aktiengesellschaft C-Ring-substituierte Pregn-4-en-21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
EP2367808A4 (en) * 2008-11-25 2012-05-09 Evestra Inc g-LACTONES OF 3- (6,6-ETHYLENE-17β-HYDROXY-3-OXO-17α-PREGEN-4-EENE-17α-YL) PROGESTATIVE PROPIONIC ACID
US8334375B2 (en) * 2009-04-10 2012-12-18 Evestra, Inc. Methods for the preparation of drospirenone
EP2266998B1 (en) 2009-06-16 2013-07-24 Crystal Pharma, S.A.U. Process for obtaining 17-spirolactones in steroids
CN101775057B (zh) * 2010-02-09 2014-07-16 浙江仙琚制药股份有限公司 屈螺酮及其中间体的制备方法
CN101830959B (zh) * 2010-05-27 2012-07-18 杭州龙山化工有限公司 一种曲螺酮的合成方法
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
WO2012107513A1 (en) 2011-02-10 2012-08-16 Crystal Pharma, S.A.U. Process for obtaining drospirenone
CN102746370A (zh) * 2011-04-22 2012-10-24 天津金耀集团有限公司 一种氧化合成孕甾11位酮基的新工艺
EA027387B1 (ru) * 2012-01-13 2017-07-31 Сэн-Гобэн Гласс Франс Дистанционная рамка для изоляционных стеклопакетов
CN102887934B (zh) * 2012-09-20 2015-05-27 杭州福斯特药业有限公司 一种屈螺酮的制备方法
US9556220B2 (en) * 2013-04-12 2017-01-31 Industriale Chimica S.R.L. Process for the preparation of drospirenone
CN104163846A (zh) * 2013-05-17 2014-11-26 上海创诺制药有限公司 一种制备曲螺酮的方法
EP3080376A1 (de) 2013-12-12 2016-10-19 Saint-Gobain Glass France Abstandshalter für isolierverglasungen mit extrudiertem dichtprofil
EP3080377B1 (de) 2013-12-12 2023-09-27 Saint-Gobain Glass France Isolierverglasung mit verbesserter abdichtung
CN104788524B (zh) * 2014-01-16 2016-07-06 浙江仙居君业药业有限公司 一种19-去甲-4-雄甾烯-3,17-二酮的制备方法
US10301868B2 (en) 2014-06-27 2019-05-28 Saint-Gobain Glass France Insulated glazing comprising a spacer, and production method
TR201815606T4 (tr) 2014-06-27 2018-11-21 Saint Gobain Mesafe parçasına sahip yalıtım cam kaplaması ve bunun imal edilmesi için yöntem ve ayrıca bunun bina cam kaplaması olarak kullanımı.
KR102056036B1 (ko) 2014-09-25 2019-12-13 쌩-고벵 글래스 프랑스 단열 글레이징 유닛용 스페이서
MX2017011083A (es) 2015-03-02 2017-11-10 Saint Gobain Separador reforzado con fibra de vidrio para unidad de acristalamiento aislante.
EP3108889A1 (en) 2015-06-23 2016-12-28 Philippe Perrin Drospirenone-based contraceptive for a female patient affected with excess weight
HRP20240121T8 (hr) 2015-06-23 2024-05-10 Laboratorios Leon Farma Sa Kontracepcija na bazi drospirenona za pacijenticu s viškom tjelesne težine

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US4069219A (en) 1976-12-27 1978-01-17 G. D. Searle & Co. 7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters
DE3026783C2 (de) 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
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AU2003285485A1 (en) * 2002-08-16 2004-03-03 Pharmacia & Upjohn Company Llc 5 ANDROSTEN-3Beta-OL STEROID INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
JP2005027184A (ja) * 2003-07-04 2005-01-27 Seiko Epson Corp 高周波複合部品
ITMI20040367A1 (it) * 2004-03-01 2004-06-01 Ind Chimica Srl Processo per la preparazione di drospirenone
ITMI20042338A1 (it) * 2004-12-06 2005-03-06 Ind Chimica Srl Processo per la preparazione di drospirenone
ATE403668T1 (de) * 2005-07-21 2008-08-15 Bayer Schering Pharma Ag Verfahren zur herstellung von 3-oxo-pregn-4-en-21,17-carbolactonen durch die metallfreie oxidation von 17-(3-hydroxypropyl)-3,17- dihydroxyandrostanen
US7319154B2 (en) * 2005-07-21 2008-01-15 Bayer Schering Pharma Ag Process for the production of 3-oxo-pregn-4-ene-21, 17-carbolactones by the metal free oxidation of 17-(3-hydroxypropyl)-3, 17-dihydroxyandrostanes
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Also Published As

Publication number Publication date
CN101223186A (zh) 2008-07-16
PL1746101T3 (pl) 2009-01-30
PE20070215A1 (es) 2007-04-11
EP1746101B2 (de) 2014-05-14
MY147795A (en) 2013-01-31
UY29686A1 (es) 2007-02-28
JP2009501753A (ja) 2009-01-22
TWI392683B (zh) 2013-04-11
US8658788B2 (en) 2014-02-25
UA100092C2 (en) 2012-11-12
AR055993A1 (es) 2007-09-12
CN101223186B (zh) 2012-09-05
JP2013177450A (ja) 2013-09-09
GT200600321A (es) 2007-02-23
DK1746101T3 (da) 2008-11-24
ES2311927T3 (es) 2009-02-16
JP5345843B2 (ja) 2013-11-20
SI1746101T2 (sl) 2014-09-30
ATE403668T1 (de) 2008-08-15
TW200716660A (en) 2007-05-01
ES2311927T5 (es) 2014-09-08
ZA200801674B (en) 2009-08-26
PT1746101E (pt) 2008-10-27
US20110275796A1 (en) 2011-11-10
DOP2006000172A (es) 2007-02-15
SI1746101T1 (sl) 2009-02-28
EP1746101B1 (de) 2008-08-06
PE20131303A1 (es) 2013-11-27
EP1746101A1 (de) 2007-01-24
SV2007002621A (es) 2007-12-12
DE502005004948D1 (de) 2008-09-18
CY1110411T1 (el) 2015-04-29
US20070049747A1 (en) 2007-03-01
PL1746101T5 (pl) 2014-11-28

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