DK1881830T3 - 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-derivater til behandling af infertilitet - Google Patents
4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-derivater til behandling af infertilitetInfo
- Publication number
- DK1881830T3 DK1881830T3 DK06743394T DK06743394T DK1881830T3 DK 1881830 T3 DK1881830 T3 DK 1881830T3 DK 06743394 T DK06743394 T DK 06743394T DK 06743394 T DK06743394 T DK 06743394T DK 1881830 T3 DK1881830 T3 DK 1881830T3
- Authority
- DK
- Denmark
- Prior art keywords
- infertility
- oxo
- phenyl
- treatment
- hexahydroquinoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05103735 | 2005-05-04 | ||
| PCT/EP2006/061972 WO2006117368A1 (en) | 2005-05-04 | 2006-05-02 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives the treatment of infertility |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1881830T3 true DK1881830T3 (da) | 2009-01-26 |
Family
ID=34939693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06743394T DK1881830T3 (da) | 2005-05-04 | 2006-05-02 | 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin-derivater til behandling af infertilitet |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8022218B2 (da) |
| EP (1) | EP1881830B1 (da) |
| JP (1) | JP5129737B2 (da) |
| KR (1) | KR20080010426A (da) |
| CN (1) | CN101212973B (da) |
| AR (1) | AR057005A1 (da) |
| AT (1) | ATE410166T1 (da) |
| AU (1) | AU2006243868B2 (da) |
| BR (1) | BRPI0611120A2 (da) |
| CA (1) | CA2606683C (da) |
| CY (1) | CY1108632T1 (da) |
| DE (1) | DE602006003094D1 (da) |
| DK (1) | DK1881830T3 (da) |
| ES (1) | ES2314908T3 (da) |
| HK (1) | HK1110025A1 (da) |
| HR (1) | HRP20080667T3 (da) |
| IL (1) | IL186748A (da) |
| MX (1) | MX2007013751A (da) |
| NO (1) | NO20075617L (da) |
| NZ (1) | NZ562686A (da) |
| PE (1) | PE20061363A1 (da) |
| PL (1) | PL1881830T3 (da) |
| PT (1) | PT1881830E (da) |
| RS (1) | RS50707B (da) |
| RU (1) | RU2412170C2 (da) |
| SI (1) | SI1881830T1 (da) |
| TW (1) | TW200719894A (da) |
| UA (1) | UA92007C2 (da) |
| WO (1) | WO2006117368A1 (da) |
| ZA (1) | ZA200709090B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| PL1879866T3 (pl) * | 2005-05-04 | 2011-07-29 | N V Organon | Pochodne dihydropirydynowe |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| US8071587B2 (en) | 2009-05-27 | 2011-12-06 | N. V. Organon | (Dihydro)imidazoiso[5,1-A]quinolines |
| TW201116531A (en) | 2009-07-29 | 2011-05-16 | Organon Nv | Ring-annulated dihydropyrrolo[2,1-a]isoquinolines |
| US8431564B2 (en) | 2009-07-29 | 2013-04-30 | Merck Sharp & Dohme B.V. | Ring-annulated dihydropyrrolo[2,1-α]isoquinolines |
| TW201116515A (en) | 2009-07-31 | 2011-05-16 | Organon Nv | Dihydrobenzoindazoles |
| JP5976011B2 (ja) | 2011-04-05 | 2016-08-23 | 武田薬品工業株式会社 | スルホンアミド誘導体およびその用途 |
| WO2014083383A1 (en) * | 2012-11-28 | 2014-06-05 | Stichting Dienst Landbouwkundig Onderzoek | Substituted dihydropyrtoines for somatic embryogenesis iν plants |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1070162B (de) | 1959-12-03 | Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M | Verfahren zur Herstellung von 5 - Brom - 3 - nitro - 4 - hydroxybenzaldehyd bzw. 5 - Chlor - 3 - nitro - 4 - hydroxybenzaldehyd | |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| DE4430639A1 (de) * | 1994-08-29 | 1996-03-07 | Bayer Ag | Verwendung von 5-substituierten Pyridin- und Hexahydrochinolin-3-carbonsäurederivaten |
| GB9515445D0 (en) * | 1995-07-27 | 1995-09-27 | Pharmacia Spa | Dihydropyridine and pyridine derivatives and process for their preparation |
| CN1200114A (zh) * | 1995-10-19 | 1998-11-25 | 武田药品工业株式会社 | 作为gnrh拮抗剂的喹啉衍生物 |
| US6593335B1 (en) | 1997-12-18 | 2003-07-15 | Abbott Laboratories | Potassium channel openers |
| ATE279407T1 (de) | 1998-08-07 | 2004-10-15 | Applied Research Systems | Fsh mimetika zur behandlung von infertilität |
| WO2002009706A1 (en) | 2000-07-27 | 2002-02-07 | Smithkline Beecham Corporation | Agonists of follicle stimulating hormone activity |
| KR100908468B1 (ko) | 2001-07-02 | 2009-07-21 | 엔.브이.오가논 | 테트라히드로퀴놀린 유도체 |
| JP2003026630A (ja) | 2001-07-13 | 2003-01-29 | Taoka Chem Co Ltd | カラーカプラー中間体用カルボン酸クロリド類の製造法 |
| TWI322012B (en) * | 2002-12-20 | 2010-03-21 | Organon Nv | Tetrahydroquinoline derivatives |
| PL1879866T3 (pl) * | 2005-05-04 | 2011-07-29 | N V Organon | Pochodne dihydropirydynowe |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
-
2006
- 2006-02-05 UA UAA200711802A patent/UA92007C2/ru unknown
- 2006-05-02 SI SI200630157T patent/SI1881830T1/sl unknown
- 2006-05-02 PT PT06743394T patent/PT1881830E/pt unknown
- 2006-05-02 EP EP06743394A patent/EP1881830B1/en active Active
- 2006-05-02 DK DK06743394T patent/DK1881830T3/da active
- 2006-05-02 KR KR1020077026919A patent/KR20080010426A/ko not_active Application Discontinuation
- 2006-05-02 JP JP2008509434A patent/JP5129737B2/ja not_active Expired - Fee Related
- 2006-05-02 NZ NZ562686A patent/NZ562686A/en not_active IP Right Cessation
- 2006-05-02 ES ES06743394T patent/ES2314908T3/es active Active
- 2006-05-02 RS RSP-2008/0582A patent/RS50707B/sr unknown
- 2006-05-02 CA CA2606683A patent/CA2606683C/en not_active Expired - Fee Related
- 2006-05-02 MX MX2007013751A patent/MX2007013751A/es active IP Right Grant
- 2006-05-02 RU RU2007144989/04A patent/RU2412170C2/ru not_active IP Right Cessation
- 2006-05-02 DE DE602006003094T patent/DE602006003094D1/de active Active
- 2006-05-02 PL PL06743394T patent/PL1881830T3/pl unknown
- 2006-05-02 BR BRPI0611120-3A patent/BRPI0611120A2/pt not_active IP Right Cessation
- 2006-05-02 AT AT06743394T patent/ATE410166T1/de active
- 2006-05-02 AU AU2006243868A patent/AU2006243868B2/en not_active Ceased
- 2006-05-02 US US11/912,736 patent/US8022218B2/en active Active
- 2006-05-02 WO PCT/EP2006/061972 patent/WO2006117368A1/en active Application Filing
- 2006-05-02 CN CN2006800237595A patent/CN101212973B/zh not_active Expired - Fee Related
- 2006-05-03 TW TW095115774A patent/TW200719894A/zh unknown
- 2006-05-03 PE PE2006000464A patent/PE20061363A1/es not_active Application Discontinuation
- 2006-05-03 AR ARP060101779A patent/AR057005A1/es unknown
-
2007
- 2007-10-18 IL IL186748A patent/IL186748A/en not_active IP Right Cessation
- 2007-10-22 ZA ZA200709090A patent/ZA200709090B/xx unknown
- 2007-11-06 NO NO20075617A patent/NO20075617L/no not_active Application Discontinuation
-
2008
- 2008-04-22 HK HK08104451A patent/HK1110025A1/xx not_active IP Right Cessation
- 2008-12-19 HR HR20080667T patent/HRP20080667T3/xx unknown
- 2008-12-22 CY CY20081101479T patent/CY1108632T1/el unknown
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