MY120156A - Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide - Google Patents

Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide

Info

Publication number
MY120156A
MY120156A MYPI98002570A MYPI9802570A MY120156A MY 120156 A MY120156 A MY 120156A MY PI98002570 A MYPI98002570 A MY PI98002570A MY PI9802570 A MYPI9802570 A MY PI9802570A MY 120156 A MY120156 A MY 120156A
Authority
MY
Malaysia
Prior art keywords
difluorobenzyl
carboxamide
triazole
crystal modification
modification
Prior art date
Application number
MYPI98002570A
Other languages
English (en)
Inventor
Robert Portmann
Urs Christoph Hofmeier
Andreas Burkhard
Walter Scherrer
Martin Szelagiewicz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4209650&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY120156(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MY120156A publication Critical patent/MY120156A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MYPI98002570A 1997-06-10 1998-06-09 Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide MY120156A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH140497 1997-06-10

Publications (1)

Publication Number Publication Date
MY120156A true MY120156A (en) 2005-09-30

Family

ID=4209650

Family Applications (2)

Application Number Title Priority Date Filing Date
MYPI98002570A MY120156A (en) 1997-06-10 1998-06-09 Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide
MYPI98002572A MY125854A (en) 1997-06-10 1998-06-09 Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
MYPI98002572A MY125854A (en) 1997-06-10 1998-06-09 Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-4-carboxamide

Country Status (36)

Country Link
US (6) US6740669B1 (forum.php)
EP (2) EP0994863B1 (forum.php)
JP (2) JP3672574B2 (forum.php)
KR (2) KR100425656B1 (forum.php)
CN (3) CN1132820C (forum.php)
AR (4) AR012945A1 (forum.php)
AT (2) ATE237599T1 (forum.php)
AU (2) AU725517B2 (forum.php)
BR (2) BR9804947A (forum.php)
CA (3) CA2256015C (forum.php)
CO (2) CO4940452A1 (forum.php)
CY (1) CY2007014I2 (forum.php)
CZ (2) CZ292481B6 (forum.php)
DE (3) DE122007000051I2 (forum.php)
DK (2) DK0994863T3 (forum.php)
ES (2) ES2192779T3 (forum.php)
FR (1) FR07C0037I2 (forum.php)
HU (2) HU225153B1 (forum.php)
ID (2) ID27660A (forum.php)
IL (2) IL125732A (forum.php)
LU (1) LU91345I2 (forum.php)
MY (2) MY120156A (forum.php)
NL (1) NL300284I2 (forum.php)
NO (2) NO329314B1 (forum.php)
NZ (2) NZ331371A (forum.php)
PE (2) PE79799A1 (forum.php)
PL (2) PL191943B1 (forum.php)
PT (1) PT994864E (forum.php)
RU (2) RU2194041C2 (forum.php)
SI (2) SI0994864T1 (forum.php)
SK (2) SK283734B6 (forum.php)
TR (2) TR199801630T1 (forum.php)
TW (2) TW526195B (forum.php)
UY (1) UY25844A1 (forum.php)
WO (2) WO1998056773A1 (forum.php)
ZA (2) ZA984967B (forum.php)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
ATE390425T1 (de) * 2002-05-31 2008-04-15 Schering Corp Xanthin-phosphodiesterase-v-hemmer polymorphe
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US7875284B2 (en) * 2006-03-10 2011-01-25 Cook Incorporated Methods of manufacturing and modifying taxane coatings for implantable medical devices
US20090069390A1 (en) * 2007-09-12 2009-03-12 Protia, Llc Deuterium-enriched rufinamide
WO2010043849A1 (en) * 2008-10-13 2010-04-22 Cipla Limited Process for the preparation of rufinamide
CN101768124B (zh) * 2008-12-30 2012-01-04 北京本草天源药物研究院 一种药物晶体及其制备方法和用途
IT1395736B1 (it) * 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
NZ598482A (en) * 2009-09-04 2014-05-30 Tactical Therapeutics Inc Novel compositions and processes for preparing 5-amino or substituted amino 1,2,3-triazoles and triazole orotate formulations
JP2013525413A (ja) * 2010-04-30 2013-06-20 ラボラトリオス レスヴィ，エス．エル． ルフィナマイド中間体の改良された製造方法
EP2465853A1 (en) * 2010-12-14 2012-06-20 Laboratorios Lesvi, S.L. Polymorph of rufinamide and process for obtaining it
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
US10206874B2 (en) 2012-07-20 2019-02-19 Hetero Research Foundation Rufinamide solid dispersion
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

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US4156734A (en) * 1976-02-13 1979-05-29 Merck & Co., Inc. Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
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US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4346097A (en) * 1980-09-30 1982-08-24 Warner-Lambert Company Method for treating convulsions with pyrazole-4-carboxamide derivatives
US4789680A (en) * 1982-12-23 1988-12-06 Ciba-Geigy Corporation Aralkyltriazole compounds
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US4511572A (en) * 1983-03-18 1985-04-16 The University Of Kentucky Research Foundation Triazoline anticonvulsant drugs
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CA2002864C (en) 1988-11-29 1999-11-16 Eddy J. E. Freyne (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives
JPH02214504A (ja) 1989-02-15 1990-08-27 Nissan Chem Ind Ltd 光学活性キノキサリン化合物の晶析法
JPH04506967A (ja) 1989-07-27 1992-12-03 ジー．ディー．サール　アンド　カンパニー 高血圧症治療用腎選択性生成物
IL96507A0 (en) 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
AU656154B2 (en) 1990-11-06 1995-01-27 Astellas Pharma Inc. Fused pyrazine derivative
JP2753911B2 (ja) 1991-12-06 1998-05-20 キッセイ薬品工業株式会社 Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法
DE4217952A1 (de) 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
US5631373A (en) 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9418443D0 (en) 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
GB9419318D0 (en) 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
KR100419355B1 (ko) 1995-02-22 2004-06-04 훽스트파마슈티칼스앤드케미칼스가부시키가이샤 무정형피레타나이드,피레타나이드다형체,이들의제조방법및이를포함하는약제학적조성물
NZ333505A (en) * 1996-07-11 2000-06-23 Novartis Ag Preparing 1-substituted 4-cyano-1,2,3-triazoles using 4-cyano-1-(2,6-difuorobenzyl)-1H-1,2,3-triazole
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use

Also Published As

Publication number Publication date
US20060116520A1 (en) 2006-06-01
NO983666D0 (no) 1998-08-11
JP2000516259A (ja) 2000-12-05
DE69811500D1 (de) 2003-03-27
CO4940448A1 (es) 2000-07-24
ATE237599T1 (de) 2003-05-15
DE69811500T2 (de) 2004-04-01
ID21014A (id) 1999-04-08
KR100425656B1 (ko) 2004-05-17
AU8437298A (en) 1998-12-30
RU2198167C2 (ru) 2003-02-10
CO4940452A1 (es) 2000-07-24
EP0994864A1 (en) 2000-04-26
HUP0000798A2 (hu) 2000-10-30
DK0994863T3 (da) 2003-05-26
PE80999A1 (es) 1999-09-06
NO983666L (no) 1998-12-17
BR9804947A (pt) 1999-08-24
AU8437198A (en) 1998-12-30
ID27660A (id) 2001-04-19
DE69813560D1 (de) 2003-05-22
HK1028242A1 (en) 2001-02-09
HU226107B1 (en) 2008-04-28
HU225153B1 (en) 2006-07-28
US7750028B2 (en) 2010-07-06
SI0994864T1 (en) 2003-10-31
NZ331370A (en) 2000-08-25
CZ253498A3 (cs) 1999-04-14
NL300284I1 (nl) 2007-10-01
NO983667D0 (no) 1998-08-11
CA2256013C (en) 2007-10-16
AR061004A2 (es) 2008-07-30
KR100409168B1 (ko) 2004-01-31
AU725528B2 (en) 2000-10-12
NL300284I2 (nl) 2007-11-01
KR19990087835A (ko) 1999-12-27
DE122007000051I1 (de) 2007-11-08
IL125732A (en) 2002-12-01
TR199801630T1 (xx) 1999-06-21
LU91345I2 (fr) 2007-09-04
HK1028241A1 (en) 2001-02-09
ES2197485T3 (es) 2004-01-01
HUP0000798A3 (en) 2000-10-30
NO329315B1 (no) 2010-09-27
NO983667L (no) 1998-12-17
CA2614926A1 (en) 1998-12-17
CN1159300C (zh) 2004-07-28
PT994864E (pt) 2003-07-31
US20030125568A1 (en) 2003-07-03
CZ253398A3 (cs) 1999-04-14
AR012946A1 (es) 2000-11-22
CY2007014I1 (el) 2009-11-04
CN1572789A (zh) 2005-02-02
IL125733A0 (en) 1999-04-11
SK283685B6 (sk) 2003-12-02
PL330764A1 (en) 1999-05-24
SK283734B6 (sk) 2003-12-02
WO1998056773A1 (en) 1998-12-17
PL330798A1 (en) 1999-06-07
FR07C0037I2 (forum.php) 2008-05-16
CZ292481B6 (cs) 2003-09-17
CA2614926C (en) 2010-02-09
ZA984967B (en) 1999-01-11
ATE232852T1 (de) 2003-03-15
HK1028031A1 (en) 2001-02-02
KR19990087836A (ko) 1999-12-27
SK109398A3 (en) 1998-12-02
JP3672575B2 (ja) 2005-07-20
NZ331371A (en) 2000-08-25
US20040167186A1 (en) 2004-08-26
CY2007014I2 (el) 2009-11-04
PL191943B1 (pl) 2006-07-31
CN1132820C (zh) 2003-12-31
DK0994864T3 (da) 2003-07-21
LU91345I9 (forum.php) 2018-12-31
US8076362B2 (en) 2011-12-13
CA2256015C (en) 2008-06-03
US6455556B2 (en) 2002-09-24
HUP0002113A2 (hu) 2001-02-28
HUP0002113A3 (en) 2002-09-30
AR061005A2 (es) 2008-07-30
BR9804946A (pt) 1999-08-24
WO1998056772A1 (en) 1998-12-17
US20010037029A1 (en) 2001-11-01
JP3672574B2 (ja) 2005-07-20
CZ292260B6 (cs) 2003-08-13
US20100310655A1 (en) 2010-12-09
TW526195B (en) 2003-04-01
ES2192779T3 (es) 2003-10-16
UY25844A1 (es) 2001-08-27
EP0994864B1 (en) 2003-04-16
TW403740B (en) 2000-09-01
SI0994863T1 (en) 2003-08-31
CN1259127A (zh) 2000-07-05
CA2256013A1 (en) 1998-12-17
TR199801631T1 (xx) 1999-06-21
PE79799A1 (es) 1999-09-03
DE69813560T2 (de) 2004-02-05
RU2194041C2 (ru) 2002-12-10
CA2256015A1 (en) 1998-12-17
CN1217716A (zh) 1999-05-26
ZA984966B (en) 1999-01-11
IL125733A (en) 2002-12-01
PL192114B1 (pl) 2006-08-31
MY125854A (en) 2006-08-30
FR07C0037I1 (forum.php) 2007-08-17
DE122007000051I2 (de) 2009-02-19
JP2000516258A (ja) 2000-12-05
EP0994863B1 (en) 2003-02-19
AU725517B2 (en) 2000-10-12
IL125732A0 (en) 1999-04-11
AR012945A1 (es) 2000-11-22
SK109498A3 (en) 1998-12-02
US6740669B1 (en) 2004-05-25
NO329314B1 (no) 2010-09-27
EP0994863A1 (en) 2000-04-26
CN1298708C (zh) 2007-02-07

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