MY110191A - 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents - Google Patents
1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agentsInfo
- Publication number
- MY110191A MY110191A MYPI93000665A MYPI19930665A MY110191A MY 110191 A MY110191 A MY 110191A MY PI93000665 A MYPI93000665 A MY PI93000665A MY PI19930665 A MYPI19930665 A MY PI19930665A MY 110191 A MY110191 A MY 110191A
- Authority
- MY
- Malaysia
- Prior art keywords
- alkoxy
- antiviral agents
- phenoxyalkylisoxazoles
- oxadiazolyl
- alkoxyalkyl
- Prior art date
Links
- 239000003443 antiviral agent Substances 0.000 title abstract 2
- -1 CYANO, 2,2,2-TRIFLUOROETHYL Chemical class 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical class F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/869,287 US5349068A (en) | 1992-04-15 | 1992-04-15 | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY110191A true MY110191A (en) | 1998-02-28 |
Family
ID=25353269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI93000665A MY110191A (en) | 1992-04-15 | 1993-04-10 | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US5349068A (enExample) |
| EP (1) | EP0566199B1 (enExample) |
| JP (1) | JP3103845B2 (enExample) |
| KR (1) | KR100314158B1 (enExample) |
| AT (1) | ATE189958T1 (enExample) |
| AU (1) | AU666528B2 (enExample) |
| CA (1) | CA2094012C (enExample) |
| CZ (1) | CZ285845B6 (enExample) |
| DE (1) | DE69327913T2 (enExample) |
| DK (1) | DK0566199T3 (enExample) |
| ES (1) | ES2143487T3 (enExample) |
| FI (1) | FI112229B (enExample) |
| GR (1) | GR3033486T3 (enExample) |
| HU (2) | HU220606B1 (enExample) |
| IL (1) | IL105372A (enExample) |
| MX (1) | MX9302169A (enExample) |
| MY (1) | MY110191A (enExample) |
| NO (1) | NO302700B1 (enExample) |
| NZ (1) | NZ247411A (enExample) |
| PH (1) | PH30454A (enExample) |
| PT (1) | PT566199E (enExample) |
| RU (1) | RU2114112C1 (enExample) |
| SG (1) | SG50663A1 (enExample) |
| SK (1) | SK279786B6 (enExample) |
| TW (1) | TW239140B (enExample) |
| UA (1) | UA35557C2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5349068A (en) * | 1992-04-15 | 1994-09-20 | Sterling Winthrop Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| US5552420A (en) * | 1994-05-13 | 1996-09-03 | Sterling Winthrop Inc. | Therapeutic phenoxyalkylazoles and phenoxyalkylazines |
| IL118657A0 (en) * | 1996-06-14 | 1996-10-16 | Arad Dorit | Inhibitors for picornavirus proteases |
| IL122591A0 (en) | 1997-12-14 | 1998-06-15 | Arad Dorit | Pharmaceutical compositions comprising cystein protease inhibitors |
| US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
| US6528652B1 (en) * | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
| AUPQ105499A0 (en) | 1999-06-18 | 1999-07-08 | Biota Scientific Management Pty Ltd | Antiviral agents |
| AUPR213700A0 (en) * | 2000-12-18 | 2001-01-25 | Biota Scientific Management Pty Ltd | Antiviral agents |
| JP2005504014A (ja) * | 2001-06-08 | 2005-02-10 | サイトビア インコーポレイテッド | カスパーゼの活性化因子およびアポトーシスの誘導因子としての置換された３−アリール−５−アリール−［１，２，４］−オキサジアゾール類および類似体、並びにその使用法 |
| US7129359B2 (en) * | 2002-07-09 | 2006-10-31 | National Health Research Institutes | Imidazolidinone compounds |
| WO2003020271A1 (en) * | 2001-08-29 | 2003-03-13 | Viropharma Incorporated | Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents |
| US20050027127A1 (en) * | 2001-08-29 | 2005-02-03 | Diana Guy D. | Oxadiazolyl-phenoxyalkylisoxazoles compositions thereof and methods for their use as anti-picornaviral agents |
| DE60236136D1 (de) | 2001-12-07 | 2010-06-10 | Ana Maria Sandino | Zusammensetzungen zur Steigerung des überlebens von Wassertieren, die einem RNS-Virus ausgesetzt sind |
| AU2003215246A1 (en) * | 2002-02-14 | 2003-09-04 | Viropharma Incorporated | Methods of reducing rhinovirus contagion and related compositions |
| CN100364531C (zh) * | 2002-12-18 | 2008-01-30 | 西托维亚公司 | 3,5－二取代－[1,2,4]－二唑及类似物和其用途 |
| US7259174B2 (en) * | 2004-05-25 | 2007-08-21 | National Health Research Institutes | Imidazolidinone compounds |
| EP1819329A2 (en) * | 2004-08-04 | 2007-08-22 | Schering Corporation | Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases |
| WO2007095039A2 (en) * | 2006-02-09 | 2007-08-23 | Schering Corporation | Pharmaceutical formulations |
| CA2641605A1 (en) * | 2006-02-09 | 2007-08-23 | Schering Corporation | Pharmaceutical formulations |
| EP1981475A2 (en) * | 2006-02-09 | 2008-10-22 | Schering Corporation | Pharmaceutical formulations |
| ES2550152T3 (es) | 2006-12-13 | 2015-11-04 | F. Hoffmann-La Roche Ag | Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa |
| KR101031584B1 (ko) * | 2009-04-21 | 2011-04-27 | 파인오토시스템(주) | 전면부가 개폐되는 차량용 적외선 조사장치 |
| CN103102322B (zh) * | 2011-11-14 | 2016-02-24 | 上海交通大学 | 噁唑类化合物及其制备方法、药物组合物及其用途 |
| KR20210046649A (ko) | 2018-08-21 | 2021-04-28 | 교린 세이야꾸 가부시키 가이샤 | 이환식 헤테로방향환 유도체 |
| US20220298149A1 (en) * | 2019-09-27 | 2022-09-22 | Collaborations Pharmaceuticals, Inc. | Isoxazole-3-carboxamide derivatives and their use for treatment of diseases caused by virus infection |
| US20230218644A1 (en) | 2020-04-16 | 2023-07-13 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861791A (en) * | 1983-08-29 | 1989-08-29 | Sterling Drug Inc. | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents |
| US4843087A (en) * | 1983-08-29 | 1989-06-27 | Sterling Drug Inc. | Di-heterocyclic compounds and their use as antiviral agents |
| ZA846525B (en) * | 1983-08-29 | 1985-04-24 | Sterling Drug Inc | (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof |
| CA1299176C (en) * | 1985-07-02 | 1992-04-21 | Guy Dominic Diana | Process for preparing isoxazole and furan derivatives |
| GB8619433D0 (en) * | 1986-08-08 | 1986-09-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| US5175178A (en) * | 1989-08-21 | 1992-12-29 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| US4945164A (en) * | 1989-08-18 | 1990-07-31 | Sterling Drug Inc. | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof |
| US4942241A (en) * | 1989-08-21 | 1990-07-17 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| NZ234760A (en) * | 1989-08-18 | 1991-09-25 | Sterling Drug Inc | Antiviral oxazole compounds and compositions |
| US5175177A (en) * | 1991-07-17 | 1992-12-29 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
| US5349068A (en) * | 1992-04-15 | 1994-09-20 | Sterling Winthrop Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
-
1992
- 1992-04-15 US US07/869,287 patent/US5349068A/en not_active Expired - Lifetime
-
1993
- 1993-03-31 TW TW082102383A patent/TW239140B/zh not_active IP Right Cessation
- 1993-04-07 CZ CZ93597A patent/CZ285845B6/cs not_active IP Right Cessation
- 1993-04-10 MY MYPI93000665A patent/MY110191A/en unknown
- 1993-04-13 SG SG1996008085A patent/SG50663A1/en unknown
- 1993-04-13 DE DE69327913T patent/DE69327913T2/de not_active Expired - Lifetime
- 1993-04-13 ES ES93201058T patent/ES2143487T3/es not_active Expired - Lifetime
- 1993-04-13 EP EP93201058A patent/EP0566199B1/en not_active Expired - Lifetime
- 1993-04-13 DK DK93201058T patent/DK0566199T3/da active
- 1993-04-13 PT PT93201058T patent/PT566199E/pt unknown
- 1993-04-13 AT AT93201058T patent/ATE189958T1/de active
- 1993-04-14 HU HU9301084A patent/HU220606B1/hu unknown
- 1993-04-14 MX MX9302169A patent/MX9302169A/es unknown
- 1993-04-14 PH PH46044A patent/PH30454A/en unknown
- 1993-04-14 NO NO19931366A patent/NO302700B1/no not_active IP Right Cessation
- 1993-04-14 CA CA002094012A patent/CA2094012C/en not_active Expired - Lifetime
- 1993-04-14 KR KR1019930006244A patent/KR100314158B1/ko not_active Expired - Lifetime
- 1993-04-14 AU AU36881/93A patent/AU666528B2/en not_active Expired
- 1993-04-14 IL IL10537293A patent/IL105372A/en not_active IP Right Cessation
- 1993-04-14 RU RU93004675A patent/RU2114112C1/ru active
- 1993-04-15 JP JP05088647A patent/JP3103845B2/ja not_active Expired - Lifetime
- 1993-04-15 NZ NZ247411A patent/NZ247411A/en not_active IP Right Cessation
- 1993-04-15 FI FI931707A patent/FI112229B/fi not_active IP Right Cessation
- 1993-04-15 SK SK353-93A patent/SK279786B6/sk not_active IP Right Cessation
- 1993-06-15 UA UA93003099A patent/UA35557C2/uk unknown
- 1993-10-01 US US08/131,050 patent/US5464848A/en not_active Expired - Lifetime
-
1995
- 1995-05-19 US US08/444,795 patent/US5643929A/en not_active Expired - Lifetime
- 1995-06-30 HU HU95P/P00642P patent/HU211320A9/hu unknown
-
2000
- 2000-05-24 GR GR20000401183T patent/GR3033486T3/el unknown
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