NO931366D0 - 1,2,4-oksadiazolylfenoksyalkylisoksazoler og deres anvendelse som antivirale midler - Google Patents

1,2,4-oksadiazolylfenoksyalkylisoksazoler og deres anvendelse som antivirale midler

Info

Publication number
NO931366D0
NO931366D0 NO931366A NO931366A NO931366D0 NO 931366 D0 NO931366 D0 NO 931366D0 NO 931366 A NO931366 A NO 931366A NO 931366 A NO931366 A NO 931366A NO 931366 D0 NO931366 D0 NO 931366D0
Authority
NO
Norway
Prior art keywords
alkoxy
antiviral agents
alkoxyalkyl
hydroxyalkyl
cycloalkyl
Prior art date
Application number
NO931366A
Other languages
English (en)
Other versions
NO931366L (no
NO302700B1 (no
Inventor
Guy Dominic Diana
Theodore John Nits
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of NO931366D0 publication Critical patent/NO931366D0/no
Publication of NO931366L publication Critical patent/NO931366L/no
Publication of NO302700B1 publication Critical patent/NO302700B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO19931366A 1992-04-15 1993-04-14 1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler NO302700B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/869,287 US5349068A (en) 1992-04-15 1992-04-15 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (3)

Publication Number Publication Date
NO931366D0 true NO931366D0 (no) 1993-04-14
NO931366L NO931366L (no) 1993-10-18
NO302700B1 NO302700B1 (no) 1998-04-14

Family

ID=25353269

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19931366A NO302700B1 (no) 1992-04-15 1993-04-14 1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler

Country Status (26)

Country Link
US (3) US5349068A (no)
EP (1) EP0566199B1 (no)
JP (1) JP3103845B2 (no)
KR (1) KR100314158B1 (no)
AT (1) ATE189958T1 (no)
AU (1) AU666528B2 (no)
CA (1) CA2094012C (no)
CZ (1) CZ285845B6 (no)
DE (1) DE69327913T2 (no)
DK (1) DK0566199T3 (no)
ES (1) ES2143487T3 (no)
FI (1) FI112229B (no)
GR (1) GR3033486T3 (no)
HU (2) HU220606B1 (no)
IL (1) IL105372A (no)
MX (1) MX9302169A (no)
MY (1) MY110191A (no)
NO (1) NO302700B1 (no)
NZ (1) NZ247411A (no)
PH (1) PH30454A (no)
PT (1) PT566199E (no)
RU (1) RU2114112C1 (no)
SG (1) SG50663A1 (no)
SK (1) SK279786B6 (no)
TW (1) TW239140B (no)
UA (1) UA35557C2 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6528652B1 (en) * 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
KR20040004705A (ko) * 2001-06-08 2004-01-13 시토비아 인크. 카스파제의 활성제 및 아폽토시스의 유도제로서의 치환된3-아릴-5-아릴-[1,2,4]-옥사디아졸과 유사체 및 이의 용도
US7129359B2 (en) * 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
CA2459375A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
CA2459376A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
ATE522212T1 (de) 2001-12-07 2011-09-15 Ana Maria Sandino Neomycin zur steigerung des überlebens von wassertieren, die einem ipnv ausgesetzt sind
US20060167109A1 (en) * 2002-02-14 2006-07-27 Pevear Daniel C Methods of reducing rhinovirus contagion and related compositions
WO2004058253A1 (en) * 2002-12-18 2004-07-15 Cytovia, Inc. 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
US7259174B2 (en) * 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds
JP2008509143A (ja) * 2004-08-04 2008-03-27 シェーリング コーポレイション 気道疾患の処置のためのプレコナリルを含む薬学的処方物
US20070202055A1 (en) * 2006-02-09 2007-08-30 Julianne Berry Pharmaceutical Formulations
MX2008010350A (es) * 2006-02-09 2008-10-31 Schering Corp Formulaciones farmaceuticas.
AR059357A1 (es) * 2006-02-09 2008-03-26 Schering Corp Formulaciones farmaceuticas
RU2469032C2 (ru) 2006-12-13 2012-12-10 Ф.Хоффманн-Ля Рош Аг Производные 2-(пиперидин-4-ил)-4-фенокси- или фениламинопиримидина в качестве ненуклеозидных ингибиторов обратной транскриптазы
KR101031584B1 (ko) * 2009-04-21 2011-04-27 파인오토시스템(주) 전면부가 개폐되는 차량용 적외선 조사장치
CN103102348B (zh) * 2011-11-14 2016-06-08 上海交通大学 噁二唑类化合物及其制备方法、药物组合物及其用途
AU2019324089B2 (en) 2018-08-21 2024-06-13 Kyorin Pharmaceutical Co., Ltd. Bicyclic heteroaromatic ring derivative
WO2021209563A1 (en) 2020-04-16 2021-10-21 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Also Published As

Publication number Publication date
CA2094012C (en) 2001-08-21
FI931707A0 (fi) 1993-04-15
KR930021637A (ko) 1993-11-22
US5643929A (en) 1997-07-01
NZ247411A (en) 1994-06-27
IL105372A0 (en) 1993-08-18
HU9301084D0 (en) 1993-06-28
DE69327913T2 (de) 2000-10-12
AU3688193A (en) 1993-10-21
FI112229B (fi) 2003-11-14
JPH0649066A (ja) 1994-02-22
DE69327913D1 (de) 2000-04-06
MY110191A (en) 1998-02-28
GR3033486T3 (en) 2000-09-29
HU220606B1 (hu) 2002-03-28
CZ285845B6 (cs) 1999-11-17
AU666528B2 (en) 1996-02-15
NO931366L (no) 1993-10-18
CA2094012A1 (en) 1993-10-16
EP0566199A1 (en) 1993-10-20
CZ59793A3 (en) 1994-02-16
DK0566199T3 (da) 2000-06-19
HUT65574A (en) 1994-07-28
US5349068A (en) 1994-09-20
IL105372A (en) 1998-12-27
JP3103845B2 (ja) 2000-10-30
US5464848A (en) 1995-11-07
TW239140B (no) 1995-01-21
PT566199E (pt) 2000-09-29
MX9302169A (es) 1993-10-01
KR100314158B1 (ko) 2002-02-19
PH30454A (en) 1997-05-28
SG50663A1 (en) 1998-07-20
HU211320A9 (en) 1995-11-28
UA35557C2 (uk) 2001-04-16
RU2114112C1 (ru) 1998-06-27
ATE189958T1 (de) 2000-03-15
SK35393A3 (en) 1994-06-08
FI931707A (fi) 1993-10-16
NO302700B1 (no) 1998-04-14
ES2143487T3 (es) 2000-05-16
EP0566199B1 (en) 2000-03-01
SK279786B6 (sk) 1999-03-12

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: SANOFI, FR

MK1K Patent expired