NO302700B1 - 1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler - Google Patents

1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler

Info

Publication number
NO302700B1
NO302700B1 NO19931366A NO931366A NO302700B1 NO 302700 B1 NO302700 B1 NO 302700B1 NO 19931366 A NO19931366 A NO 19931366A NO 931366 A NO931366 A NO 931366A NO 302700 B1 NO302700 B1 NO 302700B1
Authority
NO
Norway
Prior art keywords
compounds
antiviral agents
alkoxy
oxadiazolylphenoxyalkylisoxazoles
preparation
Prior art date
Application number
NO19931366A
Other languages
English (en)
Other versions
NO931366L (no
NO931366D0 (no
Inventor
Guy Dominic Diana
Theodore John Nitz
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO931366D0 publication Critical patent/NO931366D0/no
Publication of NO931366L publication Critical patent/NO931366L/no
Publication of NO302700B1 publication Critical patent/NO302700B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO19931366A 1992-04-15 1993-04-14 1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler NO302700B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/869,287 US5349068A (en) 1992-04-15 1992-04-15 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (3)

Publication Number Publication Date
NO931366D0 NO931366D0 (no) 1993-04-14
NO931366L NO931366L (no) 1993-10-18
NO302700B1 true NO302700B1 (no) 1998-04-14

Family

ID=25353269

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19931366A NO302700B1 (no) 1992-04-15 1993-04-14 1,2,4-oksadiazolylfenoksyalkylisoksazoler preparater inneholdende disse forbindelsene og deres anvendelse for fremstilling av antivirale midler

Country Status (26)

Country Link
US (3) US5349068A (no)
EP (1) EP0566199B1 (no)
JP (1) JP3103845B2 (no)
KR (1) KR100314158B1 (no)
AT (1) ATE189958T1 (no)
AU (1) AU666528B2 (no)
CA (1) CA2094012C (no)
CZ (1) CZ285845B6 (no)
DE (1) DE69327913T2 (no)
DK (1) DK0566199T3 (no)
ES (1) ES2143487T3 (no)
FI (1) FI112229B (no)
GR (1) GR3033486T3 (no)
HU (2) HU220606B1 (no)
IL (1) IL105372A (no)
MX (1) MX9302169A (no)
MY (1) MY110191A (no)
NO (1) NO302700B1 (no)
NZ (1) NZ247411A (no)
PH (1) PH30454A (no)
PT (1) PT566199E (no)
RU (1) RU2114112C1 (no)
SG (1) SG50663A1 (no)
SK (1) SK279786B6 (no)
TW (1) TW239140B (no)
UA (1) UA35557C2 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6528652B1 (en) 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
EP1406632A4 (en) * 2001-06-08 2009-11-04 Cytovia Inc 3-ARYL-5-ARYL-1,2,4-OXADIAZOLES AND THEIR ANALOGUES, CASPASE ACTIVATORS AND INDUCERS OF APOPTOSIS, AND USES THEREOF
US7129359B2 (en) 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
US20050027127A1 (en) * 2001-08-29 2005-02-03 Diana Guy D. Oxadiazolyl-phenoxyalkylisoxazoles compositions thereof and methods for their use as anti-picornaviral agents
WO2003020271A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
DE60236136D1 (de) 2001-12-07 2010-06-10 Ana Maria Sandino Zusammensetzungen zur Steigerung des überlebens von Wassertieren, die einem RNS-Virus ausgesetzt sind
AU2003215246A1 (en) * 2002-02-14 2003-09-04 Viropharma Incorporated Methods of reducing rhinovirus contagion and related compositions
CN100364531C (zh) * 2002-12-18 2008-01-30 西托维亚公司 3,5－二取代－[1,2,4]－二唑及类似物和其用途
US7259174B2 (en) * 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds
CA2575932A1 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
MX2008010351A (es) * 2006-02-09 2008-10-31 Schering Corp Formulaciones farmaceuticas.
AR059359A1 (es) * 2006-02-09 2008-03-26 Schering Corp Formulaciones farmaceuticas que contienen pleconaril
WO2007095039A2 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
ES2550152T3 (es) 2006-12-13 2015-11-04 F. Hoffmann-La Roche Ag Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa
KR101031584B1 (ko) * 2009-04-21 2011-04-27 파인오토시스템(주) 전면부가 개폐되는 차량용 적외선 조사장치
CN103102322B (zh) * 2011-11-14 2016-02-24 上海交通大学 噁唑类化合物及其制备方法、药物组合物及其用途
JP7309725B2 (ja) 2018-08-21 2023-07-18 杏林製薬株式会社 ２環性ヘテロ芳香環誘導体
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Also Published As

Publication number Publication date
DE69327913T2 (de) 2000-10-12
DK0566199T3 (da) 2000-06-19
FI112229B (fi) 2003-11-14
DE69327913D1 (de) 2000-04-06
CZ59793A3 (en) 1994-02-16
FI931707A0 (fi) 1993-04-15
SG50663A1 (en) 1998-07-20
PT566199E (pt) 2000-09-29
EP0566199B1 (en) 2000-03-01
AU3688193A (en) 1993-10-21
SK279786B6 (sk) 1999-03-12
IL105372A0 (en) 1993-08-18
HU211320A9 (en) 1995-11-28
MX9302169A (es) 1993-10-01
CA2094012A1 (en) 1993-10-16
GR3033486T3 (en) 2000-09-29
ATE189958T1 (de) 2000-03-15
SK35393A3 (en) 1994-06-08
EP0566199A1 (en) 1993-10-20
NO931366L (no) 1993-10-18
CA2094012C (en) 2001-08-21
CZ285845B6 (cs) 1999-11-17
MY110191A (en) 1998-02-28
US5643929A (en) 1997-07-01
US5349068A (en) 1994-09-20
HU220606B1 (hu) 2002-03-28
HU9301084D0 (en) 1993-06-28
JP3103845B2 (ja) 2000-10-30
IL105372A (en) 1998-12-27
NO931366D0 (no) 1993-04-14
NZ247411A (en) 1994-06-27
PH30454A (en) 1997-05-28
RU2114112C1 (ru) 1998-06-27
JPH0649066A (ja) 1994-02-22
ES2143487T3 (es) 2000-05-16
HUT65574A (en) 1994-07-28
KR100314158B1 (ko) 2002-02-19
KR930021637A (ko) 1993-11-22
US5464848A (en) 1995-11-07
UA35557C2 (uk) 2001-04-16
TW239140B (no) 1995-01-21
AU666528B2 (en) 1996-02-15
FI931707A (fi) 1993-10-16

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: SANOFI, FR

MK1K Patent expired