MX9204194A - Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales - Google Patents

Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales

Info

Publication number
MX9204194A
MX9204194A MX9204194A MX9204194A MX9204194A MX 9204194 A MX9204194 A MX 9204194A MX 9204194 A MX9204194 A MX 9204194A MX 9204194 A MX9204194 A MX 9204194A MX 9204194 A MX9204194 A MX 9204194A
Authority
MX
Mexico
Prior art keywords
compounds
phenoxialkylysoxazole
oxadiazolil
antiviral agents
trifluoromethyl
Prior art date
Application number
MX9204194A
Other languages
English (en)
Inventor
Diana Guy Dominic
Thomas Robert Bailey
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of MX9204194A publication Critical patent/MX9204194A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Los compuestos de la fórmula general (I), en donde Y es alquileno de 3 a 9 átomos de carbono; R1 es alquilo inferior, alcoxi inferior, ciclopropilo o trifluorometilo; R2 y R3 independientemente son hidrógeno, alquilo inferior, halógeno, alcoxi inferior, nitro, trifluorometilo o hidroxi.
MX9204194A 1991-07-17 1992-07-16 Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales MX9204194A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/731,569 US5175177A (en) 1991-07-17 1991-07-17 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (1)

Publication Number Publication Date
MX9204194A true MX9204194A (es) 1993-08-01

Family

ID=24940074

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204194A MX9204194A (es) 1991-07-17 1992-07-16 Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales

Country Status (7)

Country Link
US (1) US5175177A (es)
EP (1) EP0523803A1 (es)
JP (1) JP3288756B2 (es)
AU (1) AU660024B2 (es)
CA (1) CA2074004C (es)
IE (1) IE922334A1 (es)
MX (1) MX9204194A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04295470A (ja) * 1991-03-22 1992-10-20 Wakamoto Pharmaceut Co Ltd モノアミンオキシダーゼ−ｂ酵素阻害活性を有する１，２，４−オキサジアゾール誘導体及びその製造法
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5637708A (en) * 1994-03-07 1997-06-10 President And Fellows Of Harvard College Structure based design of capsid stabilizing or antiviral agents
WO2007095039A2 (en) * 2006-02-09 2007-08-23 Schering Corporation Pharmaceutical formulations
US20080131454A1 (en) 2006-12-05 2008-06-05 Marinomed Biotechnologie Gmbh Methods and Compositions for the Treatment of Rhinovirus Infections with Carrageenan
CN103102322B (zh) * 2011-11-14 2016-02-24 上海交通大学 噁唑类化合物及其制备方法、药物组合物及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions

Also Published As

Publication number Publication date
US5175177A (en) 1992-12-29
IE922334A1 (en) 1993-11-03
JP3288756B2 (ja) 2002-06-04
CA2074004C (en) 2003-10-07
JPH05255322A (ja) 1993-10-05
AU1850092A (en) 1993-01-21
AU660024B2 (en) 1995-06-08
EP0523803A1 (en) 1993-01-20
CA2074004A1 (en) 1993-01-18

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