MXPA04009766A - Nuevo recubrimiento de pelicula. - Google Patents
Nuevo recubrimiento de pelicula.Info
- Publication number
- MXPA04009766A MXPA04009766A MXPA04009766A MXPA04009766A MXPA04009766A MX PA04009766 A MXPA04009766 A MX PA04009766A MX PA04009766 A MXPA04009766 A MX PA04009766A MX PA04009766 A MXPA04009766 A MX PA04009766A MX PA04009766 A MXPA04009766 A MX PA04009766A
- Authority
- MX
- Mexico
- Prior art keywords
- weight
- range
- dispersion
- monomer
- film
- Prior art date
Links
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- 238000009501 film coating Methods 0.000 title claims abstract description 95
- 239000006185 dispersion Substances 0.000 claims abstract description 68
- 239000000178 monomer Substances 0.000 claims abstract description 68
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 46
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- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 22
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 22
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- 239000008194 pharmaceutical composition Substances 0.000 claims abstract description 15
- 238000013270 controlled release Methods 0.000 claims abstract description 11
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- 229960002237 metoprolol Drugs 0.000 claims description 28
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims description 4
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- RGHAZVBIOOEVQX-UHFFFAOYSA-N Metoprolol succinate Chemical compound OC(=O)CCC(O)=O.COCCC1=CC=C(OCC(O)CNC(C)C)C=C1.COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 RGHAZVBIOOEVQX-UHFFFAOYSA-N 0.000 description 9
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- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
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- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 239000000088 plastic resin Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 235000019394 potassium persulphate Nutrition 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 150000003890 succinate salts Chemical class 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical class [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/16—Aqueous medium
- C08F2/22—Emulsion polymerisation
- C08F2/24—Emulsion polymerisation with the aid of emulsifying agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/04—Acids; Metal salts or ammonium salts thereof
- C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201110A SE0201110D0 (sv) | 2002-04-12 | 2002-04-12 | New film coating |
| PCT/GB2003/001531 WO2003087180A2 (en) | 2002-04-12 | 2003-04-09 | New film coating |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04009766A true MXPA04009766A (es) | 2004-12-13 |
Family
ID=20287566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04009766A MXPA04009766A (es) | 2002-04-12 | 2003-04-09 | Nuevo recubrimiento de pelicula. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20050256255A1 (https=) |
| EP (1) | EP1497345A2 (https=) |
| JP (1) | JP2005522542A (https=) |
| KR (1) | KR20040107501A (https=) |
| CN (1) | CN100467503C (https=) |
| AU (1) | AU2003217070B2 (https=) |
| BR (1) | BR0308892A (https=) |
| CA (1) | CA2481139A1 (https=) |
| DE (1) | DE20320377U1 (https=) |
| IL (1) | IL164372A0 (https=) |
| MX (1) | MXPA04009766A (https=) |
| NO (1) | NO20044926L (https=) |
| NZ (1) | NZ535750A (https=) |
| SE (1) | SE0201110D0 (https=) |
| WO (1) | WO2003087180A2 (https=) |
| ZA (1) | ZA200407669B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
| EP1355633B1 (en) * | 2001-12-19 | 2005-01-19 | AstraZeneca AB | NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate |
| SE0202353D0 (sv) * | 2002-08-01 | 2002-08-01 | Astrazeneca Ab | New film coating |
| US8414926B1 (en) | 2006-09-12 | 2013-04-09 | University Of South Florida | Nanoparticles with covalently bound surfactant for drug delivery |
| JP5524624B2 (ja) * | 2007-11-16 | 2014-06-18 | 旭化成ケミカルズ株式会社 | 水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤 |
| EP3043778B1 (en) * | 2013-09-13 | 2017-09-06 | Bayer Pharma Aktiengesellschaft | Pharmaceutical compositions containing refametinib |
| CN103626913A (zh) * | 2013-11-14 | 2014-03-12 | 悦康药业集团安徽天然制药有限公司 | 一种甲基丙烯酸-丙烯酸乙酯共聚物水分散体肠溶型材料及其制备方法 |
| CN104758937B (zh) * | 2014-01-02 | 2019-05-21 | 石药集团中奇制药技术（石家庄）有限公司 | 一种美托洛尔缓释微丸制剂 |
| AU2015287299A1 (en) * | 2014-07-09 | 2017-02-02 | Sun Pharmaceutical Industries Limited | Capsule dosage form of metoprolol succinate |
| CN114699448A (zh) * | 2022-03-21 | 2022-07-05 | 广东省惠州市中药厂有限公司 | 糖衣片剂及其制备方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE573256A (https=) * | 1957-11-25 | |||
| US3234039A (en) * | 1961-01-16 | 1966-02-08 | Dow Chemical Co | Transparent latex finish system for exterior wood |
| DE1570223A1 (de) * | 1965-08-31 | 1970-07-09 | Aschaffenburger Zellstoffwerke | Verfahren zur Herstellung von Acryl- bzw. Methacrylpolymerisatfolien |
| GB1263148A (en) * | 1968-04-03 | 1972-02-09 | Toray Industries | Antistatic copolymers and their use in the treatment of synthetic fibers |
| US3944513A (en) * | 1969-04-29 | 1976-03-16 | Rohm And Haas Company | Purification of polymer dispersions with adsorbent carbon particles |
| DE2031871C3 (de) * | 1970-06-27 | 1974-06-27 | Roehm Gmbh, 6100 Darmstadt | Überzugsmasse für Arzneiformen |
| US4056497A (en) * | 1972-05-15 | 1977-11-01 | Hoechst Aktiengesellschaft | Acrylic ester copolymers capable of being cross-linked |
| DE2228515B1 (de) * | 1972-06-12 | 1974-02-14 | Röhm GmbH, 6100 Darmstadt | Verfahren zur herstellung von polyacrylatdispersionen |
| US3890292A (en) * | 1973-05-23 | 1975-06-17 | Daubert Chemical Co | Adhesive compositions and tapes |
| NL160278C (nl) * | 1975-09-25 | 1979-10-15 | Synres Internationaal Nv | Werkwijze voor het bereiden van waterige emulsies van additiepolymeren. |
| DE2651048A1 (de) * | 1976-11-09 | 1978-05-18 | Hoechst Ag | Kunststoffdispersion mit hoher nasshaftung und verfahren zu ihrer herstellung |
| JPS5525165A (en) * | 1978-08-12 | 1980-02-22 | Hitachi Electronics | Pulse information transmission in telemeter |
| JPS597687B2 (ja) * | 1979-09-20 | 1984-02-20 | 日東電工株式会社 | 医薬部材 |
| GB8521494D0 (en) * | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
| US4616074A (en) * | 1985-10-01 | 1986-10-07 | Alco Chemical Corporation | Acrylic-methylene succinic ester emulsion copolymers for thickening aqueous systems |
| SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
| JPH0832730B2 (ja) * | 1986-08-25 | 1996-03-29 | ライオン株式会社 | 超微粒子化ポリマ−ラテツクスの製造方法 |
| GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
| JPH01113322A (ja) * | 1987-10-23 | 1989-05-02 | Tomoaki Fukuda | アクリル系エマルジョンおよびこれを用いたｐＨ非依存性遅延放出型製剤 |
| US5085866A (en) * | 1988-12-02 | 1992-02-04 | Southern Research Institute | Method of producing zero-order controlled-released devices |
| ATE124864T1 (de) * | 1989-03-10 | 1995-07-15 | Yamanouchi Pharma Co Ltd | Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen. |
| US5292522A (en) * | 1989-06-20 | 1994-03-08 | Rohm Gmbh | Aqueous film coating agent for solid medicaments |
| CA2053005A1 (en) * | 1990-10-10 | 1992-04-11 | Achim Gopferich | Emulsifier-free emulsion polymers |
| US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
| JP3094118B2 (ja) * | 1992-10-06 | 2000-10-03 | ジェイエスアール株式会社 | コーティング用水分散体 |
| US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
| JP3405756B2 (ja) * | 1993-04-20 | 2003-05-12 | 共和薬品工業株式会社 | マイクロカプセルの皮膜材料 |
| DE9414066U1 (de) * | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| US5626655A (en) * | 1995-07-11 | 1997-05-06 | Hewlett-Packard Company | Use of co-surfactants to adjust properties of ink-jet inks |
| US5721313A (en) * | 1995-11-02 | 1998-02-24 | Rhone-Poulenc Inc. | Crosslinked polymer composition |
| US5939578A (en) * | 1996-06-21 | 1999-08-17 | Tong-Ho Lin | Vasomolol: an ultra short-acting and vasodilatory vanilloid type β.sub. - adrenoceptor antagonist |
| SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
| US6646046B2 (en) * | 2001-12-06 | 2003-11-11 | Permachel | Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition |
| EP1355633B1 (en) * | 2001-12-19 | 2005-01-19 | AstraZeneca AB | NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate |
| SE0202353D0 (sv) * | 2002-08-01 | 2002-08-01 | Astrazeneca Ab | New film coating |
-
2002
- 2002-04-12 SE SE0201110A patent/SE0201110D0/xx unknown
-
2003
- 2003-04-09 BR BR0308892-8A patent/BR0308892A/pt not_active IP Right Cessation
- 2003-04-09 JP JP2003584135A patent/JP2005522542A/ja active Pending
- 2003-04-09 EP EP03712458A patent/EP1497345A2/en not_active Withdrawn
- 2003-04-09 CA CA002481139A patent/CA2481139A1/en not_active Abandoned
- 2003-04-09 KR KR10-2004-7016214A patent/KR20040107501A/ko not_active Ceased
- 2003-04-09 MX MXPA04009766A patent/MXPA04009766A/es active IP Right Grant
- 2003-04-09 CN CNB038132001A patent/CN100467503C/zh not_active Expired - Fee Related
- 2003-04-09 AU AU2003217070A patent/AU2003217070B2/en not_active Ceased
- 2003-04-09 NZ NZ535750A patent/NZ535750A/xx unknown
- 2003-04-09 DE DE20320377U patent/DE20320377U1/de not_active Expired - Lifetime
- 2003-04-09 WO PCT/GB2003/001531 patent/WO2003087180A2/en not_active Ceased
- 2003-04-09 US US10/511,115 patent/US20050256255A1/en not_active Abandoned
-
2004
- 2004-09-22 ZA ZA200407669A patent/ZA200407669B/en unknown
- 2004-10-03 IL IL16437204A patent/IL164372A0/xx unknown
- 2004-11-11 NO NO20044926A patent/NO20044926L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20050256255A1 (en) | 2005-11-17 |
| AU2003217070B2 (en) | 2009-02-26 |
| JP2005522542A (ja) | 2005-07-28 |
| EP1497345A2 (en) | 2005-01-19 |
| NO20044926L (no) | 2005-01-11 |
| WO2003087180A3 (en) | 2003-11-20 |
| CN1659196A (zh) | 2005-08-24 |
| CN100467503C (zh) | 2009-03-11 |
| WO2003087180A2 (en) | 2003-10-23 |
| SE0201110D0 (sv) | 2002-04-12 |
| BR0308892A (pt) | 2005-01-18 |
| NZ535750A (en) | 2006-03-31 |
| ZA200407669B (en) | 2005-10-06 |
| AU2003217070A1 (en) | 2003-10-27 |
| CA2481139A1 (en) | 2003-10-23 |
| IL164372A0 (en) | 2005-12-18 |
| KR20040107501A (ko) | 2004-12-20 |
| DE20320377U1 (de) | 2004-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |