MX9606494A - Compuestos organicos. - Google Patents

Compuestos organicos.

Info

Publication number
MX9606494A
MX9606494A MX9606494A MX9606494A MX9606494A MX 9606494 A MX9606494 A MX 9606494A MX 9606494 A MX9606494 A MX 9606494A MX 9606494 A MX9606494 A MX 9606494A MX 9606494 A MX9606494 A MX 9606494A
Authority
MX
Mexico
Prior art keywords
organic compounds
adhesion molecule
molecule expression
r1leu
cyclopeptolides
Prior art date
Application number
MX9606494A
Other languages
English (en)
Inventor
Michael Morris Dreyfuss
Carolyn Ann Foster
Hans-Ulrich Naegeli
Berndt Oberhauser
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415168A external-priority patent/GB9415168D0/en
Priority claimed from GBGB9504332.9A external-priority patent/GB9504332D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of MX9606494A publication Critical patent/MX9606494A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Botany (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)

Abstract

Los ciclopeptolidos de la formula I: en donde A, B, R1Leu, Leu, C, X e Y son como se definen, son inhibidores de la expresion de las moléculas de adhesion y de esta manera son utiles para el tratamiento de enfermedades inflamatorias y otras que comprenden niveles incrementados de la expresion de las moléculas de adhesion.
MX9606494A 1994-07-27 1995-07-26 Compuestos organicos. MX9606494A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9415168A GB9415168D0 (en) 1994-07-27 1994-07-27 Organic compounds
GBGB9504332.9A GB9504332D0 (en) 1995-03-03 1995-03-03 Organic compounds
PCT/EP1995/002966 WO1996003430A1 (en) 1994-07-27 1995-07-26 Organic compounds

Publications (1)

Publication Number Publication Date
MX9606494A true MX9606494A (es) 1997-03-29

Family

ID=26305345

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9606494A MX9606494A (es) 1994-07-27 1995-07-26 Compuestos organicos.

Country Status (26)

Country Link
US (1) US6013627A (es)
EP (1) EP0775158B1 (es)
JP (1) JP3425763B2 (es)
KR (1) KR100378974B1 (es)
CN (1) CN1116304C (es)
AT (1) ATE187461T1 (es)
AU (1) AU702332B2 (es)
BR (1) BR9508342A (es)
CA (1) CA2192786C (es)
CY (1) CY2225B1 (es)
CZ (1) CZ289311B6 (es)
DE (1) DE69513837T2 (es)
DK (1) DK0775158T3 (es)
ES (1) ES2142490T3 (es)
FI (1) FI970279A (es)
GR (1) GR3032698T3 (es)
HK (1) HK1014011A1 (es)
HU (1) HUT77388A (es)
MX (1) MX9606494A (es)
NO (1) NO970340D0 (es)
NZ (1) NZ291168A (es)
PL (1) PL181990B1 (es)
PT (1) PT775158E (es)
RU (1) RU2155772C2 (es)
SK (1) SK11797A3 (es)
WO (1) WO1996003430A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
US6011136A (en) * 1995-11-21 2000-01-04 Novartis Ag Cyclopeptolides
WO1999014082A1 (en) 1996-09-18 1999-03-25 Minnesota Mining And Manufacturing Company Adhesively-bonded inflatable restraint and method of making
US6365619B1 (en) 1999-07-22 2002-04-02 Novartis Ag Treatment of arteriosclerosis
EP1212331B1 (en) * 1999-08-24 2004-04-21 Ariad Gene Therapeutics, Inc. 28-epirapalogs
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
AU2002223649A1 (en) * 2000-10-27 2002-05-06 Novartis Ag Vegh inhibitors and their use
GB0028367D0 (en) * 2000-11-21 2001-01-03 Celltech Chiroscience Ltd Chemical compounds
GB0101598D0 (en) * 2001-01-22 2001-03-07 Novartis Ag Organic compounds
EP1594459B1 (en) 2002-12-30 2010-02-17 Angiotech International Ag Drug delivery from rapid gelling polymer composition
WO2009089549A1 (en) 2008-01-11 2009-07-16 Massachusetts Eye & Ear Infirmary Conditional-stop dimerizable caspase transgenic animals
US9593356B2 (en) 2013-06-11 2017-03-14 Takara Bio Usa, Inc. Protein enriched microvesicles and methods of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443367A (en) * 1982-04-08 1984-04-17 Monsanto Company Peptide and peptolide substrates for mammalian collagenase
US4425428A (en) * 1982-04-08 1984-01-10 Monsanto Company Novel peptide and peptolide substrates for mammalian collagenase
DE3851268T2 (de) * 1987-06-19 1995-01-26 Sandoz Ag Zyklische Peptolide.
DE3832059A1 (de) * 1988-09-21 1990-03-29 Howaldtswerke Deutsche Werft Tauchtiefengesteuerte ausblasventil-einrichtung
DE3832362A1 (de) * 1988-09-23 1990-03-29 Sandoz Ag Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
CZ289311B6 (cs) 2001-12-12
HUT77388A (hu) 1998-04-28
US6013627A (en) 2000-01-11
PL181990B1 (pl) 2001-10-31
PT775158E (pt) 2000-05-31
AU3222195A (en) 1996-02-22
CZ22197A3 (en) 1997-05-14
DE69513837T2 (de) 2000-05-18
ATE187461T1 (de) 1999-12-15
AU702332B2 (en) 1999-02-18
CY2225B1 (en) 2003-04-18
NZ291168A (en) 1998-06-26
DK0775158T3 (da) 2000-05-22
JPH10504540A (ja) 1998-05-06
CN1116304C (zh) 2003-07-30
BR9508342A (pt) 1997-10-21
FI970279A0 (fi) 1997-01-23
EP0775158A1 (en) 1997-05-28
HK1014011A1 (en) 1999-09-17
NO970340L (no) 1997-01-27
GR3032698T3 (en) 2000-06-30
PL317349A1 (en) 1997-04-01
CN1154705A (zh) 1997-07-16
KR100378974B1 (ko) 2003-10-08
DE69513837D1 (de) 2000-01-13
JP3425763B2 (ja) 2003-07-14
WO1996003430A1 (en) 1996-02-08
RU2155772C2 (ru) 2000-09-10
ES2142490T3 (es) 2000-04-16
CA2192786A1 (en) 1996-02-08
NO970340D0 (no) 1997-01-27
CA2192786C (en) 2009-06-16
EP0775158B1 (en) 1999-12-08
FI970279A (fi) 1997-01-23
SK11797A3 (en) 1997-07-09

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees