MX9207374A - Preparacion farmaceutica que comprende una hormonade crecimiento o un derivado de la hormona de crecimiento e histidina o un derivado de histidina. - Google Patents
Preparacion farmaceutica que comprende una hormonade crecimiento o un derivado de la hormona de crecimiento e histidina o un derivado de histidina.Info
- Publication number
- MX9207374A MX9207374A MX9207374A MX9207374A MX9207374A MX 9207374 A MX9207374 A MX 9207374A MX 9207374 A MX9207374 A MX 9207374A MX 9207374 A MX9207374 A MX 9207374A MX 9207374 A MX9207374 A MX 9207374A
- Authority
- MX
- Mexico
- Prior art keywords
- histidine
- derivative
- growth hormone
- pharmaceutical preparation
- dissolved
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Abstract
Se proporciona una preparación farmacéutica que comprende una hormona del crecimiento e histidina o un derivado de histidina, como aditivo o sustancia amortiguadora que muestra una muy alta estabilidad contra la desamidación, oxidación y ruptura o separación de los enlaces peptídicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK204691A DK204691D0 (da) | 1991-12-20 | 1991-12-20 | Hidtil ukendt farmaceutisk praeparat |
DK136492A DK136492D0 (da) | 1992-11-10 | 1992-11-10 | A pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9207374A true MX9207374A (es) | 1993-07-01 |
Family
ID=26065653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9207374A MX9207374A (es) | 1991-12-20 | 1992-12-17 | Preparacion farmaceutica que comprende una hormonade crecimiento o un derivado de la hormona de crecimiento e histidina o un derivado de histidina. |
Country Status (24)
Country | Link |
---|---|
EP (2) | EP0618807B1 (es) |
JP (2) | JP2950617B2 (es) |
KR (1) | KR100266502B1 (es) |
AT (2) | ATE227583T1 (es) |
AU (1) | AU667503B2 (es) |
BG (1) | BG63075B1 (es) |
CA (1) | CA2125855C (es) |
CZ (1) | CZ283361B6 (es) |
DE (3) | DE10399015I1 (es) |
DK (1) | DK0618807T3 (es) |
ES (2) | ES2291264T3 (es) |
FI (1) | FI115116B (es) |
HU (1) | HUT69402A (es) |
IL (1) | IL104152A (es) |
MX (1) | MX9207374A (es) |
NL (1) | NL300126I1 (es) |
NO (1) | NO942300L (es) |
NZ (1) | NZ246556A (es) |
PT (1) | PT618807E (es) |
RO (1) | RO111990B1 (es) |
RU (1) | RU2122426C1 (es) |
SK (1) | SK279641B6 (es) |
UA (1) | UA41502C2 (es) |
WO (1) | WO1993012812A1 (es) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6022858A (en) * | 1991-12-20 | 2000-02-08 | Novo Nordisk A/S | Pharmaceutical formulation of human-growth hormone pretreated with zinc salt |
DK204791D0 (da) * | 1991-12-20 | 1991-12-20 | Novo Nordisk As | Hidtil ukendt farmaceutisk praeparat |
US5849700A (en) * | 1991-12-20 | 1998-12-15 | Novo Nordisk A/S | Pharmaceutical formulation |
US5849704A (en) * | 1991-12-20 | 1998-12-15 | Novo Nordisk A/S | Pharmaceutical formulation |
US6288030B1 (en) * | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
DE69420872T2 (de) * | 1994-06-17 | 2000-01-13 | Applied Research Systems | Hgh enthaltende pharmazeutische zubereitungen |
TW426737B (en) * | 1994-06-27 | 2001-03-21 | Hayashibara Biochem Lab | Saccharide composition with reduced reducibility, and preparation and uses thereof |
IL115592A (en) * | 1994-10-13 | 2000-07-26 | Novo Nordisk As | Stabilized pharmaceutical formulation comprising a growth hormone and leucine |
US5547696A (en) * | 1994-10-13 | 1996-08-20 | Novo Nordisk A/S | Pharmaceutical formulation |
US5654278A (en) * | 1994-10-13 | 1997-08-05 | Novo Nordisk A/S | Composition and method comprising growth hormone and leucine |
US5631225A (en) * | 1994-10-13 | 1997-05-20 | Novo Nordisk A/S | Pharmaceutical formulation |
US5705482A (en) * | 1995-01-13 | 1998-01-06 | Novo Nordisk A/S | Pharmaceutical formulation |
WO1996021460A1 (en) * | 1995-01-13 | 1996-07-18 | Novo Nordisk A/S | A stabilized pharmaceutical formulation comprising a growth hormone and x-lys |
ZA96122B (en) * | 1995-01-13 | 1996-07-24 | Novo Nordisk As | A pharmaceutical formulation |
US5552385A (en) * | 1995-06-05 | 1996-09-03 | Novo Nordisk A/S | Pharmaceutical formulation |
US6936289B2 (en) | 1995-06-07 | 2005-08-30 | Danisco A/S | Method of improving the properties of a flour dough, a flour dough improving composition and improved food products |
ZA965367B (en) * | 1995-07-12 | 1997-01-23 | Novo Nordisk As | A pharmaceutical formulation |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
KR100236393B1 (ko) * | 1996-02-02 | 1999-12-15 | 나까니시 히로유끼 | 사람성장호르몬을 함유하는 의약제제 |
US20020077461A1 (en) * | 1996-04-24 | 2002-06-20 | Soren Bjorn | Pharmaceutical formulation |
US20070179096A1 (en) | 1996-04-24 | 2007-08-02 | Novo Nordisk A/S | Pharmaceutical Formulation |
CN1278737A (zh) * | 1997-11-12 | 2001-01-03 | 阿尔萨公司 | 减少多肽自结合的方法 |
EP2311436A1 (en) * | 1998-04-27 | 2011-04-20 | Altus Pharmaceuticals Inc. | Stabilized protein crystals, formulations containing them and methods of making them |
KR20080011353A (ko) * | 2000-02-24 | 2008-02-01 | 몬산토 테크놀로지 엘엘씨 | 소마토트로핀의 지속적인 방출을 위한 비수성 주사제제들 |
US6719992B2 (en) | 2000-06-26 | 2004-04-13 | Monsanto Technology Llc | Non-aqueous surfactant-containing formulations for extended release of somatotropin |
US6664234B1 (en) | 2000-06-30 | 2003-12-16 | Monsanto Technology Llc | Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin |
EP1309312A2 (en) | 2000-08-07 | 2003-05-14 | Inhale Therapeutic Systems, Inc. | Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation |
PT1314437E (pt) | 2000-08-11 | 2014-08-29 | Chugai Pharmaceutical Co Ltd | Preparações estabilizadas contendo anticorpo |
BR0209154A (pt) | 2001-05-18 | 2004-07-20 | Danisco | Processo de preparação de uma massa com uma enzima |
EP1585771A4 (en) * | 2002-12-31 | 2006-11-29 | Altus Pharmaceuticals Inc | COMPLEXES OF PROTEIN CRYSTALS AND IONIC POLYMERS |
SG176314A1 (en) | 2002-12-31 | 2011-12-29 | Altus Pharmaceuticals Inc | Human growth hormone crystals and methods for preparing them |
BRPI0413276B8 (pt) | 2003-08-05 | 2021-05-25 | Novo Nordisk As | derivado de insulina, complexo de zinco do mesmo, e, composição farmacêutica |
DK1776455T3 (da) | 2004-07-16 | 2015-06-22 | Dupont Nutrition Biosci Aps | Lipolytisk enzym, anvendelser deraf i fødevareindustrien |
PT1827483E (pt) * | 2004-12-15 | 2014-09-25 | Swedish Orphan Biovitrum Ab Publ | Formulações terapêuticas do fator de crescimento de queratinócitos |
US7816320B2 (en) * | 2004-12-22 | 2010-10-19 | Ambrx, Inc. | Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35 |
RU2008105545A (ru) * | 2005-08-30 | 2009-10-10 | Ново Нордиск Хелс Кеа Аг (Ch) | Жидкие препараты пэгилированного гормона роста |
WO2007033427A1 (en) * | 2005-09-23 | 2007-03-29 | Metabolic Pharmaceuticals Limited | Stabilisation of peptides with basic amino acids |
EP2505593A1 (en) | 2005-12-28 | 2012-10-03 | Novo Nordisk A/S | Compositions comprising an acylated insulin and zinc and method of making the said compositions |
CN101495155A (zh) | 2006-07-07 | 2009-07-29 | 诺沃-诺迪斯克保健股份有限公司 | 新的蛋白结合物及其制备方法 |
US8071544B2 (en) * | 2006-12-18 | 2011-12-06 | Althea Technologies, Inc. | Crystallized recombinant human growth factor formulations |
WO2008152106A1 (en) | 2007-06-13 | 2008-12-18 | Novo Nordisk A/S | Pharmaceutical formulation comprising an insulin derivative |
ES2607003T3 (es) | 2008-10-30 | 2017-03-28 | Novo Nordisk A/S | Tratamiento de diabetes mellitus utilizando inyecciones de insulina con una frecuencia de inyección inferior a la diaria |
EP2889043B1 (en) * | 2008-12-16 | 2019-04-10 | Genzyme Corporation | Synthetic intermediates for preparing oligosaccharide-protein conjugates |
WO2010096394A2 (en) | 2009-02-17 | 2010-08-26 | Redwood Biosciences, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
CN107674121A (zh) | 2009-12-21 | 2018-02-09 | Ambrx 公司 | 经过修饰的牛促生长素多肽和其用途 |
CN104017063A (zh) | 2009-12-21 | 2014-09-03 | Ambrx公司 | 经过修饰的猪促生长素多肽和其用途 |
JP5924343B2 (ja) * | 2010-09-21 | 2016-05-25 | フェリング ベスローテン フェンノートシャップ | 組換えヒト成長ホルモン産生の改善された方法 |
RU2013123515A (ru) | 2010-10-27 | 2014-12-10 | Ново Нордиск А/С | Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами |
AU2012205301B2 (en) | 2011-01-14 | 2017-01-05 | Redwood Bioscience, Inc. | Aldehyde-tagged immunoglobulin polypeptides and method of use thereof |
DK2854764T3 (en) | 2012-06-05 | 2019-04-08 | Neuroderm Ltd | COMPOSITIONS CONTAINING APOMORPHINE AND ORGANIC ACIDS, AND APPLICATIONS THEREOF |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
US10137172B2 (en) | 2013-04-30 | 2018-11-27 | Novo Nordisk A/S | Administration regime |
US11559580B1 (en) * | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
AU2015416589B2 (en) * | 2015-12-10 | 2021-04-01 | Menicon Co., Ltd. | Peptide composition |
AU2017257504A1 (en) | 2016-04-26 | 2018-10-25 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
BR112020023860A2 (pt) * | 2018-05-25 | 2021-04-13 | Dr. Reddy's Laboratories Ltd. | Formulação estável de proteína de fusão, e, métodos para obter uma formulação estável e para aumentar a estabilidade de proteína de fusão |
US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
WO2022197963A1 (en) * | 2021-03-19 | 2022-09-22 | Pfizer Inc. | Long-acting growth hormone compositions |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4917685A (en) * | 1986-05-16 | 1990-04-17 | International Minerals & Chem. Corp. | Delivery device for the administration of stabilized growth promoting hormones |
US4816568A (en) * | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
EP0374120A3 (en) * | 1988-12-13 | 1991-07-31 | Monsanto Company | Comosition for controlled release of polypeptides |
DK168790D0 (es) * | 1990-07-13 | 1990-07-13 | Novo Nordisk As |
-
1992
- 1992-12-16 AT AT93902089T patent/ATE227583T1/de active
- 1992-12-16 HU HU9401832A patent/HUT69402A/hu unknown
- 1992-12-16 RO RO94-01056A patent/RO111990B1/ro unknown
- 1992-12-16 DE DE10399015C patent/DE10399015I1/de active Granted
- 1992-12-16 DE DE69232847T patent/DE69232847T2/de not_active Expired - Lifetime
- 1992-12-16 CA CA002125855A patent/CA2125855C/en not_active Expired - Lifetime
- 1992-12-16 DK DK93902089T patent/DK0618807T3/da active
- 1992-12-16 AT AT01128974T patent/ATE368472T1/de not_active IP Right Cessation
- 1992-12-16 EP EP93902089A patent/EP0618807B1/en not_active Expired - Lifetime
- 1992-12-16 KR KR1019940702139A patent/KR100266502B1/ko not_active IP Right Cessation
- 1992-12-16 SK SK754-94A patent/SK279641B6/sk not_active IP Right Cessation
- 1992-12-16 WO PCT/DK1992/000379 patent/WO1993012812A1/en active IP Right Grant
- 1992-12-16 CZ CZ941507A patent/CZ283361B6/cs not_active IP Right Cessation
- 1992-12-16 UA UA94005308A patent/UA41502C2/uk unknown
- 1992-12-16 DE DE69233704T patent/DE69233704T2/de not_active Expired - Lifetime
- 1992-12-16 JP JP5511361A patent/JP2950617B2/ja not_active Expired - Lifetime
- 1992-12-16 PT PT93902089T patent/PT618807E/pt unknown
- 1992-12-16 EP EP01128974A patent/EP1197222B1/en not_active Expired - Lifetime
- 1992-12-16 AU AU33446/93A patent/AU667503B2/en not_active Ceased
- 1992-12-16 ES ES01128974T patent/ES2291264T3/es not_active Expired - Lifetime
- 1992-12-16 ES ES93902089T patent/ES2185625T3/es not_active Expired - Lifetime
- 1992-12-16 NZ NZ246556A patent/NZ246556A/en unknown
- 1992-12-16 RU RU94045932A patent/RU2122426C1/ru active
- 1992-12-17 MX MX9207374A patent/MX9207374A/es active IP Right Grant
- 1992-12-18 IL IL104152A patent/IL104152A/en not_active IP Right Cessation
-
1994
- 1994-05-30 BG BG98806A patent/BG63075B1/bg unknown
- 1994-06-17 NO NO942300A patent/NO942300L/no not_active Application Discontinuation
- 1994-06-17 FI FI942906A patent/FI115116B/fi not_active IP Right Cessation
-
1999
- 1999-02-03 JP JP11026405A patent/JPH11315031A/ja active Pending
-
2003
- 2003-05-01 NL NL300126C patent/NL300126I1/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9207374A (es) | Preparacion farmaceutica que comprende una hormonade crecimiento o un derivado de la hormona de crecimiento e histidina o un derivado de histidina. | |
NO942299D0 (no) | Stabilisert, farmasöytisk preparat som omfatter veksthormon og asparagin | |
ES2173197T3 (es) | Una formula farmaceutica que contiene hormona de crecimiento e isoleucina. | |
KR970706840A (ko) | 성장호르몬 및 발린으로 이루어진 약학적 조성물(a pharmaceutical formulation comprising a growth hormone and valine) | |
ATE213953T1 (de) | Ein wachstumshormon und leucin enthaltende pharmazeutische formulierung | |
MX9800309A (es) | Formulacion farmaceutica estabilizada que comprende una hormona del crecimiento y un peptido que comprende al menos un residuo de aminoacido basico y al menos un residuo de aminoacido acido. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
PD | Change of proprietorship |
Owner name: NOVO NORDISK HEALTH CARE AG |