MX352875B - Proceso para elaborar composiciones hemostaticas secas y estables. - Google Patents

Proceso para elaborar composiciones hemostaticas secas y estables.

Info

Publication number
MX352875B
MX352875B MX2012013999A MX2012013999A MX352875B MX 352875 B MX352875 B MX 352875B MX 2012013999 A MX2012013999 A MX 2012013999A MX 2012013999 A MX2012013999 A MX 2012013999A MX 352875 B MX352875 B MX 352875B
Authority
MX
Mexico
Prior art keywords
component
dry
stable hemostatic
hemostatic composition
final container
Prior art date
Application number
MX2012013999A
Other languages
English (en)
Other versions
MX2012013999A (es
Inventor
Goessl Andreas
J Reich Cary
Edward Osawa Atsushi
Original Assignee
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44626885&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX352875(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Healthcare Sa filed Critical Baxter Healthcare Sa
Publication of MX2012013999A publication Critical patent/MX2012013999A/es
Publication of MX352875B publication Critical patent/MX352875B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/104—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

La presente invención se refiere a un procedimiento para elaborar una composición hemostática seca y estable, dicho procedimiento comprende a) proporcionar un primer componente que comprende una preparación seca de un agente que induce la coagulación, b) proporcionar un segundo componente que comprende una preparación de un polímero biocompatible adecuado para utilizarse en hemostasis, c) mezclar dicho primer componente y dicho segundo componente bajo condiciones efectivas para formar una pasta mojada mientras que evita esencialmente la degradación del segundo componente mediante dicho primer componente en un contenedor final o transferir dicha pasta mojada en un contenedor final, d) congelar y liofilizar dicha pasta en dicho contenedor, obteniendo de esta manera una composición hemostática seca y estable que comprende dicho primer y dicho segundo componentes en forma liofilizada, y e) terminar dicha composición hemostática seca y estable en dicho contenedor final para un dispositivo farmacéutico que se puede almacenar que contiene dicho primer componente y dicho segundo componente en una forma combinada en la forma de una composición hemostática seca y estable.
MX2012013999A 2010-06-01 2011-06-01 Proceso para elaborar composiciones hemostaticas secas y estables. MX352875B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35021410P 2010-06-01 2010-06-01
PCT/EP2011/059114 WO2011151400A1 (en) 2010-06-01 2011-06-01 Process for making dry and stable hemostatic compositions

Publications (2)

Publication Number Publication Date
MX2012013999A MX2012013999A (es) 2013-01-28
MX352875B true MX352875B (es) 2017-12-13

Family

ID=44626885

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012013999A MX352875B (es) 2010-06-01 2011-06-01 Proceso para elaborar composiciones hemostaticas secas y estables.

Country Status (12)

Country Link
US (1) US9408945B2 (es)
EP (1) EP2575776B1 (es)
JP (3) JP6289096B2 (es)
KR (1) KR101865427B1 (es)
CN (1) CN102917691A (es)
AU (1) AU2011260274B2 (es)
BR (1) BR112012030457B1 (es)
CA (1) CA2801120C (es)
CO (1) CO6660509A2 (es)
ES (1) ES2682302T3 (es)
MX (1) MX352875B (es)
WO (1) WO2011151400A1 (es)

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