ES2167330T3 - Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion. - Google Patents

Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion.

Info

Publication number
ES2167330T3
ES2167330T3 ES93905057T ES93905057T ES2167330T3 ES 2167330 T3 ES2167330 T3 ES 2167330T3 ES 93905057 T ES93905057 T ES 93905057T ES 93905057 T ES93905057 T ES 93905057T ES 2167330 T3 ES2167330 T3 ES 2167330T3
Authority
ES
Spain
Prior art keywords
preparation
use procedure
ceramic compositions
injectable ceramic
ceramic matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93905057T
Other languages
English (en)
Inventor
Donald G Wallace
Hugh Mcmullin
George Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiotech Biomaterials Corp
Original Assignee
Cohesion Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cohesion Technologies Inc filed Critical Cohesion Technologies Inc
Application granted granted Critical
Publication of ES2167330T3 publication Critical patent/ES2167330T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/10Ceramics or glasses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Abstract

COMPOSICIONES IMPLANTABLES INYECTABLES QUE CONTIENEN UNA MATRIZ DE CERAMICA BIOCOMPATIBLE PRESENTE EN UN SOPORTE FLUIDO, DONDE LA MATRIZ DE CERAMICA CONTIENE PARTICULAS QUE TIENEN UNA DISTRIBUCION DIMENSIONAL DE ENTRE 50 (MU)M Y 250 (MU)M. OPCIONALMENTE, LAS COMPOSICIONES PUEDE TENER ADEMAS COLAGENO, DONDE LAS CANTIDADES RELATIVAS DE COLAGENO Y DE MATRIZ DE CERAMICA DETERMINAN, AL MENOS EN PARTE, LAS PROPIEDADES FISICAS DE LOS IMPLANTES FORMADOS A BASE DE INYECTAR LAS COMPOSICIONES. EL SOPORTE FLUIDO ES UN MEDIO ACUOSO TAMPONADO, QUE NORMALMENTE INCLUYE UN MATERIAL BASE POLIMERICO ORGANICO CUANDO LA COMPOSICION NO CONTIENE COLAGENO. LAS COMPOSICIONES SON PARTICULARMENTE ADECUADAS PARA REPARAR Y AUMENTAR LOS TEJIDOS BLANDOS Y DUROS MEDIANTE INYECCIONES.
ES93905057T 1992-02-28 1993-02-16 Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion. Expired - Lifetime ES2167330T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84364692A 1992-02-28 1992-02-28

Publications (1)

Publication Number Publication Date
ES2167330T3 true ES2167330T3 (es) 2002-05-16

Family

ID=25290604

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93905057T Expired - Lifetime ES2167330T3 (es) 1992-02-28 1993-02-16 Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion.

Country Status (9)

Country Link
US (1) US5352715A (es)
EP (2) EP1120439B1 (es)
JP (1) JPH07504106A (es)
AT (2) ATE269371T1 (es)
AU (1) AU666712B2 (es)
CA (1) CA2128783C (es)
DE (2) DE69333556T2 (es)
ES (1) ES2167330T3 (es)
WO (1) WO1993016657A1 (es)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US5219895A (en) * 1991-01-29 1993-06-15 Autogenesis Technologies, Inc. Collagen-based adhesives and sealants and methods of preparation and use thereof
DE69233022T2 (de) 1991-11-04 2004-02-12 Genetics Institute, LLC, Cambridge Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US6537574B1 (en) * 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US7060287B1 (en) * 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
ATE319823T1 (de) 1993-12-07 2006-03-15 Inst Genetics Llc Bmp-12, bmp-13 und diese enthaltende sehne- induzierende zusammensetzungen
US7150879B1 (en) 1995-05-19 2006-12-19 Etex Corporation Neutral self-setting calcium phosphate paste
US6132463A (en) 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US6027742A (en) 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US6541037B1 (en) 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
US6117456A (en) * 1995-05-19 2000-09-12 Etex Corporation Methods and products related to the physical conversion of reactive amorphous calcium phosphate
US5752974A (en) * 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
US5981412A (en) * 1996-05-01 1999-11-09 University Of Florida Research Foundation Bioactive ceramics and method of preparing bioactive ceramics
US5840290A (en) * 1996-05-30 1998-11-24 University Of Florida Research Foundation Injectable bio-active glass in a dextran suspension
US6051247A (en) * 1996-05-30 2000-04-18 University Of Florida Research Foundation, Inc. Moldable bioactive compositions
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
US7320962B2 (en) 1996-08-27 2008-01-22 Baxter International Inc. Hemoactive compositions and methods for their manufacture and use
US6063061A (en) * 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US7871637B2 (en) 1996-08-27 2011-01-18 Baxter International Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US5834008A (en) 1996-09-19 1998-11-10 U.S. Biomaterials Corp. Composition and method for acceleration of wound and burn healing
US6756060B1 (en) 1996-09-19 2004-06-29 Usbiomaterials Corp. Anti-inflammatory and antimicrobial uses for bioactive glass compositions
US6953594B2 (en) 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US7517539B1 (en) 1996-10-16 2009-04-14 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
ES2299183T3 (es) 1996-10-16 2008-05-16 Etex Corporation Composiciones bioceramicas.
US8728536B2 (en) * 1996-10-16 2014-05-20 Etex Corporation Chemotherapeutic composition using nanocrystalline calcium phosphate paste
US6417247B1 (en) * 1997-10-14 2002-07-09 Beth L. Armstrong Polymer/ceramic composites
US6423343B1 (en) 1998-01-23 2002-07-23 Usbiomaterials Corporation Bioactive glass treatment of inflammation in skin conditions
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US6224629B1 (en) * 1998-12-09 2001-05-01 Purzer Pharmaceuticals Co. Ltd. Bone substitute composition and process of preparation thereof
US6383519B1 (en) * 1999-01-26 2002-05-07 Vita Special Purpose Corporation Inorganic shaped bodies and methods for their production and use
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
CA2361421A1 (en) 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
DE60020526T2 (de) 1999-02-04 2006-05-11 SDGI Holdings, Inc., Wilmington Osteogene pastenzusammensetzungen und ihre verwendung
CA2372384C (en) 1999-04-29 2009-04-07 Usbiomaterials Corporation Anti-inflammatory bioactive glass particulates
WO2000076486A1 (en) 1999-06-14 2000-12-21 Imperial College Innnovations Silver-containing, sol-gel derived bioglass compositions
WO2001003709A1 (en) 1999-07-08 2001-01-18 Cap Biotechnology, Inc. Calcium-containing structures and methods of making and using the same
US6458162B1 (en) * 1999-08-13 2002-10-01 Vita Special Purpose Corporation Composite shaped bodies and methods for their production and use
US6183498B1 (en) 1999-09-20 2001-02-06 Devore Dale P. Methods and products for sealing a fluid leak in a tissue
EP2286847A1 (en) * 1999-10-15 2011-02-23 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
EP1475109A1 (en) * 1999-10-15 2004-11-10 Genetics Institute, LLC Formulations for delivery of osteogenic proteins
ATE284230T1 (de) * 1999-10-15 2004-12-15 Inst Genetics Llc Zusammensetzungen zur abgabe osteogener proteine
US7004977B2 (en) 1999-11-24 2006-02-28 A Enterprises, Inc. Soft tissue substitute and method of soft tissue reformation
US6521244B1 (en) * 2000-06-13 2003-02-18 Nozomu Kanesaka Body filling material
DE10032220A1 (de) * 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
DE10054857B4 (de) * 2000-11-06 2005-02-17 Bohmann, Anton, Dr.med., Dipl.-Ing. (FH) System zur Herstellung von individuell formbarem Knochenersatz
WO2002040071A1 (fr) * 2000-11-14 2002-05-23 Osteogenesis Co., Ltd. Compositions stimulant la formation d'un os ou d'un parodonte et injections pour la formation d'un os ou d'un parodonte
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
JP2004533276A (ja) * 2001-01-25 2004-11-04 リジェネレーション テクノロジーズ インク. 注射可能な多孔性骨グラフト材料
US20020176893A1 (en) * 2001-02-02 2002-11-28 Wironen John F. Compositions, implants, methods, and kits for closure of lumen openings, repair of ruptured tissue, and for bulking of tissue
US6685626B2 (en) 2001-02-02 2004-02-03 Regeneration Technologies, Inc. Compositions, devices, methods, and kits for induction of adhesions
EP1399023B1 (en) 2001-06-01 2008-04-30 Wyeth COMPOSITIONS FOR SYSTEMIC ADMINISTRATION OF SEQUENCES ENCODING BONE MORPHOGENETIC PROTEINS& x9;
TWI267378B (en) * 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20030026770A1 (en) * 2001-07-25 2003-02-06 Szymaitis Dennis W. Periodontal regeneration composition and method of using same
US7105182B2 (en) 2001-07-25 2006-09-12 Szymaitis Dennis W Periodontal regeneration composition and method of using same
MXPA04011337A (es) * 2002-05-17 2005-07-01 Wyeth Corp Portadores de acido hialuronico solidos y susceptibles de ser inyectados para la liberacion de proteinas osteogenicas.
US7273523B2 (en) * 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
US7842300B2 (en) * 2002-07-31 2010-11-30 Dentsply International, Inc. Bone repair putty
WO2004105825A1 (ja) * 2003-01-10 2004-12-09 Taki Chemical Co., Ltd. 骨形成用生体材料、該材料を含む注入用製剤、及び該材料を調製するためのキット、並びにこれらを用いる骨形成方法
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
JP5189763B2 (ja) * 2003-04-11 2013-04-24 エテックス コーポレーション 骨誘導性骨材料
US8834864B2 (en) 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
BRPI0413720A (pt) 2003-09-12 2006-10-17 Wyeth Corp bastões e pastas sólidas de fosfato de cálcio injetável para liberação de proteìnas osteogênicas
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
US7189263B2 (en) 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US20070190101A1 (en) * 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
CA2562675A1 (en) * 2004-04-15 2005-12-15 Etex Corporation Delayed-setting calcium phosphate pastes
MXPA06012420A (es) 2004-04-27 2007-03-28 Kyphon Inc Composiciones de sustitucion del hueso y metodos de uso de las mismas.
US9220595B2 (en) 2004-06-23 2015-12-29 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof
US8127770B2 (en) * 2004-08-30 2012-03-06 Spineovations, Inc. Method of using an implant for treament of ligaments and tendons
EP1788986A1 (en) 2004-08-30 2007-05-30 Spineovations, Inc. Method of treating spinal internal disk derangement
WO2006046155A2 (en) 2004-10-25 2006-05-04 Polyzenix Gmbh Loadable polyphosphazene-comprising particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
JP2008518956A (ja) * 2004-11-01 2008-06-05 バイオサンテ ファーマシューティカルズ,インコーポレイティド 化粧又は美容薬品のための使用における治療用リン酸カルシウム、及び製造方法、及び使用
DE102005034420A1 (de) * 2004-12-23 2006-07-06 Ossacur Ag Gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten
MX2007011591A (es) * 2005-03-30 2007-12-10 Wyeth Corp Metodo para estimular el crecimiento de cabello administrando bmps.
US7416602B2 (en) * 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
US7459018B2 (en) 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
EP1893174A2 (en) * 2005-05-10 2008-03-05 Cytophil, Inc. Injectable hydrogels and methods of making and using same
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
AU2007207429A1 (en) 2006-01-19 2007-07-26 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials
US9034356B2 (en) 2006-01-19 2015-05-19 Warsaw Orthopedic, Inc. Porous osteoimplant
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
DE102006011211A1 (de) * 2006-03-02 2007-09-06 Ossacur Ag Material zur Behandlung von Knochen- und/oder Knorpeldefekten
US7754005B2 (en) * 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
ES2575933T3 (es) 2006-05-31 2016-07-04 Baxter International Inc. Colágeno para su uso en la prevención de la formación de fibrosis epidural después de cirugía espinal
US7507286B2 (en) * 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
EP2422822A1 (en) * 2006-06-29 2012-02-29 Orthovita, Inc. Bioactive bone graft substitute
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
DE102006042142A1 (de) * 2006-09-06 2008-03-27 Curasan Ag Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung
US20080075788A1 (en) * 2006-09-21 2008-03-27 Samuel Lee Diammonium phosphate and other ammonium salts and their use in preventing clotting
WO2008041846A2 (en) * 2006-10-05 2008-04-10 Cam Aesthetics B.V. I.O. Hydroxyapatite tissue filler and its preparation and use
US20080096976A1 (en) * 2006-10-24 2008-04-24 Neville Alleyne Method of treating spinal internal disk derangement
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080299172A1 (en) * 2007-06-04 2008-12-04 Stuart Young Tissue repair implant
FR2918658B1 (fr) * 2007-07-09 2010-12-03 Centre Nat Rech Scient Verres bioactifs dopes en strontium.
CA2703103C (en) 2007-10-30 2017-05-09 Baxter Healthcare S.A. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
US20090131867A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system with cavity creation element
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
RU2545810C2 (ru) 2008-02-29 2015-04-10 Ферросан Медикал Дивайсиз А/С Устройство для ускорения остановки кровотечения и/или заживления ран
US20100004700A1 (en) * 2008-03-05 2010-01-07 Neville Alleyne Method of treating tissue with a suspenson of tricalcium hydroxyapatite microspheres
US8469961B2 (en) * 2008-03-05 2013-06-25 Neville Alleyne Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints
US7968616B2 (en) * 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
US20100016808A1 (en) * 2008-07-17 2010-01-21 Bioform Medical, Inc. Thin-Walled Delivery System
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
MX2011013795A (es) 2009-06-16 2012-04-30 Baxter Int Esponja hemostatica.
CA2784432C (en) 2009-12-16 2019-01-15 Baxter Healthcare S.A. Hemostatic sponge
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
WO2011137377A1 (en) 2010-04-29 2011-11-03 Dfine, Inc. System for use in treatment of vertebral fractures
US9408945B2 (en) 2010-06-01 2016-08-09 Baxter International Inc. Process for making dry and stable hemostatic compositions
CA2801116C (en) 2010-06-01 2019-02-12 Baxter International Inc. Process for making dry and stable hemostatic compositions
CN103037845B (zh) 2010-06-01 2015-11-25 巴克斯特国际公司 用于制备干燥、稳定的止血组合物的方法
WO2012062360A1 (en) 2010-11-10 2012-05-18 Stryker Trauma Gmbh Polymeric bone foam composition and method
WO2012068135A1 (en) 2010-11-15 2012-05-24 Zimmer Orthobiologics, Inc. Bone void fillers
US9447169B2 (en) 2011-03-04 2016-09-20 Orthovita, Inc. Flowable collagen-based hemostat and methods of use
US9265830B2 (en) 2011-04-20 2016-02-23 Warsaw Orthopedic, Inc. Implantable compositions and methods for preparing the same
JP6195569B2 (ja) 2011-10-11 2017-09-13 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 止血組成物
MX346958B (es) 2011-10-11 2017-04-06 Baxter Int Composición hemostatica.
KR101975624B1 (ko) 2011-10-27 2019-05-07 백스터 인터내셔널 인코포레이티드 지혈 조성물
JP6241624B2 (ja) 2012-03-06 2017-12-06 フェロサン メディカル デバイシーズ エイ/エス 止血ペーストを収容する加圧容器
KR101306748B1 (ko) * 2012-03-29 2013-09-10 주식회사 바이오알파 성장인자 전달속도 조절이 가능한 히알루론산-인산칼슘 복합체 및 그 제조방법
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
WO2014041531A1 (en) 2012-09-13 2014-03-20 Amir Avraham Delivery devices and methods for skin augmentation
US10434040B2 (en) 2012-10-08 2019-10-08 Anteis S.A. Injectable sterile aqueous formulation based on crosslinked hyaluronic acid and hydroxyapatite for aesthetic use
US10463762B2 (en) 2012-10-08 2019-11-05 Anteis S.A. Injectable sterile aqueous formulation based on crosslinked hyaluronic acid and hydroxyapatite for aesthetic use
RU2648450C2 (ru) 2012-10-08 2018-03-26 Антеис С.А. Приемлемая для инъекций стерильная водная композиция на основе сшитой гиалуроновой кислоты и гидроксиапатита для применения в пластической хирургии
US9272072B1 (en) 2012-10-19 2016-03-01 Nuvasive, Inc. Osteoinductive bone graft substitute
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
EP3079731B1 (en) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
CA2957263A1 (en) * 2014-08-05 2016-02-11 The University Of Memphis Compositions and methods for enhancing healing and regeneration of bone and soft tissue
AU2015333206B2 (en) 2014-10-13 2019-07-11 Ferrosan Medical Devices A/S. Dry composition for use in haemostasis and wound healing
CN107206165B (zh) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 用于保持并混合第一和第二物质的注射器
KR102024447B1 (ko) 2015-01-16 2019-11-14 스파인오베이션즈, 인크. 척추 디스크를 치료하기 위한 작용제 및 작용제를 포함하는 의료 키트
US10195305B2 (en) 2015-03-24 2019-02-05 Orthovita, Inc. Bioactive flowable wash-out resistant bone graft material and method for production thereof
WO2017005590A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
JP2019534130A (ja) 2016-10-27 2019-11-28 ディーファイン,インコーポレイティド セメント送達チャネルを有する関節接合型骨刀
US11026744B2 (en) 2016-11-28 2021-06-08 Dfine, Inc. Tumor ablation devices and related methods
US10463380B2 (en) 2016-12-09 2019-11-05 Dfine, Inc. Medical devices for treating hard tissues and related methods
WO2018129180A1 (en) 2017-01-06 2018-07-12 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
AU2018230378A1 (en) 2017-03-09 2019-10-31 Baxter Healthcare Sa Solvent deposition system and methods
PL3544643T3 (pl) 2017-12-14 2020-12-28 Geistlich Pharma Ag Materiał zastępczy kości
ES2900259T3 (es) * 2017-12-14 2022-03-16 Geistlich Pharma Ag Uso de una composición de implante seco para la preparación de una formulación de un implante acuoso inyectable
AU2019266529A1 (en) 2018-05-09 2020-12-03 Ethicon Inc. Method for preparing a haemostatic composition
US11937864B2 (en) 2018-11-08 2024-03-26 Dfine, Inc. Ablation systems with parameter-based modulation and related devices and methods
ES2939083T3 (es) * 2019-06-14 2023-04-18 Geistlich Pharma Ag Formulación acuosa de implante inyectable que contiene ácido ascórbico
US10960107B2 (en) 2019-06-14 2021-03-30 Geistlich Pharma Ag Collagen matrix or granulate blend of bone substitute material
US11498880B2 (en) 2019-07-26 2022-11-15 Warsaw Orthopedic, Inc. Calcium phosphate granules and methods of making them
US11433159B2 (en) * 2019-07-26 2022-09-06 Warsaw Orthopedic, Inc. Hydratable and flowable implantable compositions and methods of making and using them

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3325111A1 (de) * 1983-07-12 1985-01-24 Merck Patent Gmbh, 6100 Darmstadt Implantationsmaterialien
JPS6117409A (ja) * 1984-07-02 1986-01-25 Meishin Toryo Kk 非晶質リン酸カルシウムの製法およびこれを主成分とする生体適応性組成物
US5001169A (en) * 1984-10-24 1991-03-19 Collagen Corporation Inductive collagen-based bone repair preparations
US4563350A (en) * 1984-10-24 1986-01-07 Collagen Corporation Inductive collagen based bone repair preparations
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
US4992226A (en) * 1985-03-28 1991-02-12 Collagen Corporation Method of making molds with xenogeneic collagen/mineral preparations for bone repair
US4776890A (en) * 1985-12-18 1988-10-11 Collagen Corporation Preparation of collagen hydroxyapatite matrix for bone repair
CA1294876C (en) * 1986-04-22 1992-01-28 Karl A. Piez Marrow/collagen/mineral matrix for bone defect repair
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
US4743229A (en) * 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4865602A (en) * 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
US4863732A (en) * 1987-12-16 1989-09-05 Collagen Corporation Injectable composition for inductive bone repair
ZA93506B (en) * 1992-02-11 1994-05-11 Bristol Myers Squibb Co Soft tissue augmentation material

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JPH07504106A (ja) 1995-05-11
EP0627899B1 (en) 2001-11-07
CA2128783A1 (en) 1993-09-02
DE69333556D1 (de) 2004-07-22
WO1993016657A1 (en) 1993-09-02
ATE208217T1 (de) 2001-11-15
AU666712B2 (en) 1996-02-22
EP1120439B1 (en) 2004-06-16
DE69331096T2 (de) 2002-08-14
EP0627899A4 (en) 1996-11-13
DE69333556T2 (de) 2005-06-30
AU3619693A (en) 1993-09-13
ATE269371T1 (de) 2004-07-15
DE69331096D1 (de) 2001-12-13
CA2128783C (en) 2004-10-12
EP0627899A1 (en) 1994-12-14
US5352715A (en) 1994-10-04
EP1120439A1 (en) 2001-08-01

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