ES2140082T3 - Composiciones peptidicas con actividad de tipo factor de crecimiento. - Google Patents
Composiciones peptidicas con actividad de tipo factor de crecimiento.Info
- Publication number
- ES2140082T3 ES2140082T3 ES96913807T ES96913807T ES2140082T3 ES 2140082 T3 ES2140082 T3 ES 2140082T3 ES 96913807 T ES96913807 T ES 96913807T ES 96913807 T ES96913807 T ES 96913807T ES 2140082 T3 ES2140082 T3 ES 2140082T3
- Authority
- ES
- Spain
- Prior art keywords
- activity
- growth factor
- peptide compositions
- factor type
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE HA SINTETIZADO UN PEPTIDO CON LA SECUENCIA ANVAENA (SEC ID N :1). ESTE PEPTIDO, DENOMINADO CITOMODULINA , ES CAPAZ DE IMITAR UNA AMPLIA GAMA DE ACTIVIDADES DE TGF OS TIPOS CELULARES. SE DESCRIBEN COMPOSICIONES PARA APLICACIONES TALES COMO LA REPARACION DE TEJIDOS, QUE INCLUYEN UNA MATRIZ BIOCOMPATIBLE QUE PRESENTA CITOMODULINA MEZCLADA CON LA MATRIZ, O PORTADA POR ESTA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/431,954 US5661127A (en) | 1995-05-01 | 1995-05-01 | Peptide compositions with growth factor-like activity |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2140082T3 true ES2140082T3 (es) | 2000-02-16 |
Family
ID=23714154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96913807T Expired - Lifetime ES2140082T3 (es) | 1995-05-01 | 1996-04-18 | Composiciones peptidicas con actividad de tipo factor de crecimiento. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5661127A (es) |
EP (1) | EP0824545B1 (es) |
JP (1) | JPH11506427A (es) |
KR (1) | KR19990008239A (es) |
CN (1) | CN1183103A (es) |
AT (1) | ATE187458T1 (es) |
AU (1) | AU709197B2 (es) |
CA (1) | CA2218161C (es) |
DE (1) | DE69605544T2 (es) |
ES (1) | ES2140082T3 (es) |
NZ (1) | NZ307338A (es) |
WO (1) | WO1996034881A1 (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030077825A1 (en) * | 1994-07-22 | 2003-04-24 | Bhatnagar Rajendra S. | Structures useful for bone engineering and methods |
US5786327A (en) | 1993-03-12 | 1998-07-28 | Gensci Regeneration Sciences Inc. | Bone stimulating factor, methods of isolating same, and methods of increasing bone growth comprising administering same |
US5780436A (en) * | 1995-05-01 | 1998-07-14 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
US6638912B2 (en) * | 1995-05-01 | 2003-10-28 | The Regents Of The University Of California | Peptide compositions mimicking TGF-β activity |
US6117839A (en) * | 1995-06-07 | 2000-09-12 | Gensci Regeneration Sciences, Inc. | Bone stimulating factor |
US6352973B1 (en) | 1995-06-07 | 2002-03-05 | Osteopharm Inc. | Bone stimulating factor |
US6693081B2 (en) | 1995-09-26 | 2004-02-17 | Osteopharm Inc. | Bone stimulating factor |
AU2763099A (en) | 1998-06-22 | 2000-01-10 | Charles E. Worden | Enriched platelet wound healant |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US20030229393A1 (en) * | 2001-03-15 | 2003-12-11 | Kutryk Michael J. B. | Medical device with coating that promotes cell adherence and differentiation |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US20070055367A1 (en) * | 2000-03-15 | 2007-03-08 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence and differentiation |
US8460367B2 (en) * | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
EP1263484B1 (en) | 2000-03-15 | 2007-05-16 | OrbusNeich Medical, Inc. | Coating which promotes endothelial cell adherence |
US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
US7671018B2 (en) * | 2000-08-30 | 2010-03-02 | University Of Delaware | Delivery system for heparin-binding growth factors |
US6509318B1 (en) * | 2000-09-29 | 2003-01-21 | The Regents Of The University Of California | TGF-B inhibitors and methods |
US6815421B1 (en) * | 2001-03-22 | 2004-11-09 | Osteopharm Inc. | Polypeptides for use in ameliorating effects of aging in mammals |
CA2508765A1 (en) * | 2002-12-05 | 2004-06-17 | Osteopharm Inc. | Bone growth factor |
TW200605910A (en) * | 2004-04-30 | 2006-02-16 | Orbus Medical Technologies Inc | Medical device with coating for capturing genetically-altered cells and methods for using same |
US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
US20060293228A1 (en) * | 2005-06-24 | 2006-12-28 | Bhatnagar Rajendra S | Therapeutic compositions and methods using transforming growth factor-beta mimics |
US20060293227A1 (en) * | 2005-06-24 | 2006-12-28 | Bhatnagar Rajendra S | Cosmetic compositions and methods using transforming growth factor-beta mimics |
US8048443B2 (en) | 2005-12-16 | 2011-11-01 | Cerapedics, Inc. | Pliable medical device and method of use |
WO2007139589A1 (en) * | 2006-05-26 | 2007-12-06 | Bristol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
ITRM20060409A1 (it) * | 2006-07-31 | 2008-02-01 | Cnr Consiglio Naz Delle Ric Er | Sequenza prptidica isolata nel dominio il tipo-immunoglobulina del recettore 1 del fattore di crescita dell'endotelio vascolare e legante l'integrina a5b1 ad attivita' proangiogenica |
AU2009240888B2 (en) | 2008-04-30 | 2014-10-09 | Genomix Co., Ltd. | Method for collecting functional cells in vivo with high efficiency |
JP5865703B2 (ja) | 2009-10-28 | 2016-02-17 | 株式会社ジェノミックス | 骨髄間葉系および/または多能性幹細胞の血中動員による組織再生促進剤 |
PT2703487T (pt) | 2011-04-26 | 2018-10-11 | Genomix Co Ltd | Péptido para induzir a regeneração de um tecido e a sua utilização |
FR2992555A1 (fr) * | 2012-06-28 | 2014-01-03 | Svr Rech | Combinaison dermocosmetique depigmentante et eclaircissante |
KR102146815B1 (ko) * | 2012-10-25 | 2020-08-21 | 가부시키가이샤 스템림 | Hmgb1 단편을 이용한 신규 심근경색의 치료법 |
AU2013335685B2 (en) | 2012-10-25 | 2017-10-12 | Osaka University | Novel method for treating spinal cord injury using HMGB1 fragment |
US20160000682A1 (en) | 2014-07-02 | 2016-01-07 | Geoffrey Brooks Consultants Llc | Peptide-Based Compositions and Methods of Use |
EP3197474B1 (en) | 2014-09-26 | 2023-06-07 | Rajendra Sahai Bhatnagar | Inhibitors of nf kappa-b activity for treatment of diseases and disorders |
US9943566B2 (en) * | 2016-03-16 | 2018-04-17 | Geoffrey Brooks Consultants, Llc | NF-κB inhibitor composition for skin health |
EP3556378A4 (en) | 2017-01-27 | 2020-11-18 | StemRIM Inc. | THERAPEUTIC AGENT FOR CARDIOMYOPATHY, OLD MYOCARDINAL INFARM AND CHRONIC HEART FAILURE |
CN111542335A (zh) | 2017-12-01 | 2020-08-14 | 斯特姆里姆有限公司 | 炎症性肠病的治疗药 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5240912A (en) * | 1983-05-09 | 1993-08-31 | Todaro George J | Transforming growth factor (TGF) peptides |
US5284763A (en) * | 1985-03-22 | 1994-02-08 | Genentech, Inc. | Nucleic acid encoding TGF-β and its uses |
IL76079A (en) * | 1985-08-13 | 1991-03-10 | Univ Ramot | Collagen implants |
US4975526A (en) * | 1989-02-23 | 1990-12-04 | Creative Biomolecules, Inc. | Bone collagen matrix for zenogenic implants |
US5178845A (en) * | 1988-04-20 | 1993-01-12 | Norian Corporation | Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite |
US5055447A (en) * | 1988-07-28 | 1991-10-08 | Genentech, Inc. | Method and compositions for the treatment and prevention of septic shock |
US5236905A (en) * | 1988-08-25 | 1993-08-17 | Oncogen | In vitro method of inhibition of HIV using transforming growth factor-.beta. |
US5258029A (en) * | 1988-09-29 | 1993-11-02 | Collagen Corporation | Method for improving implant fixation |
US5268455A (en) * | 1989-05-25 | 1993-12-07 | Genentech, Inc. | Process for making biologically active polypeptides based on transforming growth factor-βsequences |
US5324519A (en) * | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
US5158934A (en) * | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
US5364839A (en) * | 1990-06-18 | 1994-11-15 | Genetics Institute, Inc. | Osteoinductive pharmaceutical formulations |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
US5208219A (en) * | 1991-02-14 | 1993-05-04 | Celtrix Pharmaceuticals Inc. | Method for inducing bone growth |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
CA2122491A1 (en) * | 1991-10-31 | 1993-05-13 | Herbert Y. Lin | Tgf-.beta. type receptor cdnas and uses therefor |
KR100259827B1 (ko) * | 1991-11-04 | 2000-06-15 | 브루스 엠. 에이센, 토마스 제이 데스로저 | 재조합 골형태 형성 단백질 헤테로다이머, 그 조성물 및 사용방법 |
US5322933A (en) * | 1992-05-07 | 1994-06-21 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Crystal structure of TGF-β-2 |
US5420243A (en) * | 1993-01-26 | 1995-05-30 | Celtrix Pharmaceuticals, Inc. | Biologically active TGF-β2 peptides |
US6040431A (en) * | 1995-06-07 | 2000-03-21 | Stryker Corporation | Single chain analogs of the TGF-β superfamily (morphons) |
-
1995
- 1995-05-01 US US08/431,954 patent/US5661127A/en not_active Expired - Fee Related
-
1996
- 1996-04-18 DE DE69605544T patent/DE69605544T2/de not_active Expired - Fee Related
- 1996-04-18 CN CN96193633A patent/CN1183103A/zh active Pending
- 1996-04-18 AT AT96913807T patent/ATE187458T1/de not_active IP Right Cessation
- 1996-04-18 CA CA002218161A patent/CA2218161C/en not_active Expired - Fee Related
- 1996-04-18 JP JP8533330A patent/JPH11506427A/ja not_active Withdrawn
- 1996-04-18 ES ES96913807T patent/ES2140082T3/es not_active Expired - Lifetime
- 1996-04-18 WO PCT/US1996/005374 patent/WO1996034881A1/en not_active Application Discontinuation
- 1996-04-18 KR KR1019970707765A patent/KR19990008239A/ko not_active Application Discontinuation
- 1996-04-18 EP EP96913807A patent/EP0824545B1/en not_active Expired - Lifetime
- 1996-04-18 NZ NZ307338A patent/NZ307338A/en unknown
- 1996-04-18 AU AU56650/96A patent/AU709197B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CN1183103A (zh) | 1998-05-27 |
KR19990008239A (ko) | 1999-01-25 |
US5661127A (en) | 1997-08-26 |
DE69605544D1 (de) | 2000-01-13 |
AU709197B2 (en) | 1999-08-26 |
CA2218161C (en) | 2008-02-05 |
CA2218161A1 (en) | 1996-11-07 |
ATE187458T1 (de) | 1999-12-15 |
WO1996034881A1 (en) | 1996-11-07 |
EP0824545A1 (en) | 1998-02-25 |
AU5665096A (en) | 1996-11-21 |
EP0824545A4 (en) | 1998-05-20 |
JPH11506427A (ja) | 1999-06-08 |
DE69605544T2 (de) | 2000-05-31 |
NZ307338A (en) | 1998-06-26 |
EP0824545B1 (en) | 1999-12-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2140082T3 (es) | Composiciones peptidicas con actividad de tipo factor de crecimiento. | |
DE69329903D1 (de) | Bioabbaubare polymere zur zelltransplantation | |
DK0720482T3 (da) | Prosaposin og cytokin-afledte peptider som terapeutiske midler | |
AU4753297A (en) | Peptide compositions with growth factor-like activity | |
RU94045952A (ru) | Домен ингибитора протеазы, днк, вектор, клетка, способ получения ингибитора протеазы, фармацевтическая композиция, применение домена | |
WO1995001439A3 (en) | Plants having modified response to ethylene | |
KR0180256B1 (en) | Bpc peptides, their preparation and use | |
AU4218389A (en) | Peptide compounds | |
ES2196088T3 (es) | Analogos del factor de crecimiento de los queratinocitos. | |
AU3258197A (en) | Peptides | |
AU6378994A (en) | Plant promoter, microorganisms and plant cells containing a unit for the expression of a protein of interest comprising said promoter | |
BR9609801A (pt) | Petídos cíclicos análogos de somatostina com atividade inibitória do desenvolvimento de hormónio | |
ATE174927T1 (de) | Haemoregulatorische penta-oder hexapeptide | |
EP1295943A4 (en) | POLYPEPTIDES CAPABLE THE POWER TO STIMULATE NEUTROPHILES | |
CA2158960A1 (en) | Plant promoter, microorganisms and plant cells containing a unit for the expression of a protein of interest comprising said promoter |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 824545 Country of ref document: ES |