ES2196088T3 - Analogos del factor de crecimiento de los queratinocitos. - Google Patents
Analogos del factor de crecimiento de los queratinocitos.Info
- Publication number
- ES2196088T3 ES2196088T3 ES95938216T ES95938216T ES2196088T3 ES 2196088 T3 ES2196088 T3 ES 2196088T3 ES 95938216 T ES95938216 T ES 95938216T ES 95938216 T ES95938216 T ES 95938216T ES 2196088 T3 ES2196088 T3 ES 2196088T3
- Authority
- ES
- Spain
- Prior art keywords
- analogs
- queratinocitos
- growth factor
- kgf
- deletion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003102 growth factor Substances 0.000 title 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE DISPONEN NUEVOS ANALOGOS DE PROTEINAS DE KGF QUE COMPRENDE UN CAMBIO DE CARGA MEDIANTE LA SUPRESION O SUSTITUCION DE UNO O MAS RESIDUOS DE AMINOACIDO 41-154 DE LA FIGURA 2 (AMINOACIDOS 72185 DE N QUE LA MOLECULA DE KGF PADRE CORRESPONDIENTE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32333794A | 1994-10-13 | 1994-10-13 | |
US48782595A | 1995-06-07 | 1995-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2196088T3 true ES2196088T3 (es) | 2003-12-16 |
Family
ID=26983900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95938216T Expired - Lifetime ES2196088T3 (es) | 1994-10-13 | 1995-10-12 | Analogos del factor de crecimiento de los queratinocitos. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0785950B1 (es) |
JP (2) | JP4422210B2 (es) |
AT (1) | ATE237634T1 (es) |
AU (1) | AU3893195A (es) |
CA (1) | CA2202390C (es) |
DE (1) | DE69530404T2 (es) |
DK (1) | DK0785950T3 (es) |
ES (1) | ES2196088T3 (es) |
HU (1) | HUT78069A (es) |
MX (1) | MX9702665A (es) |
NO (1) | NO971621L (es) |
PT (1) | PT785950E (es) |
SI (1) | SI0785950T1 (es) |
WO (1) | WO1996011951A2 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU681405B2 (en) | 1993-06-29 | 1997-08-28 | Chiron Corporation | A truncated keratinocyte growth factor (KGF) having increased biological activity |
US7084119B2 (en) | 1993-06-29 | 2006-08-01 | Chiron Corporation | Truncated keratinocyte growth factor (KGF) having increased biological activity |
EP1334981B1 (en) * | 1994-10-13 | 2011-01-26 | Swedish Orphan Biovitrum AB (publ) | Method for purifying keratinocyte growth factors |
US7232667B2 (en) | 1995-02-14 | 2007-06-19 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 polynucleotides |
US6077692A (en) | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
US6693077B1 (en) | 1995-02-14 | 2004-02-17 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
IL127872A0 (en) | 1996-07-19 | 1999-10-28 | Amgen Inc | Analogs of cationic proteins |
US6743422B1 (en) | 1996-10-15 | 2004-06-01 | Amgen, Inc. | Keratinocyte growth factor-2 products |
SI0935652T1 (en) * | 1996-10-15 | 2004-06-30 | Amgen Inc. | Keratinocyte growth factor-2 products |
GB2322132B (en) * | 1996-10-15 | 1999-09-22 | Amgen Inc | Keratinocyte growth factor-2 products |
US6869927B1 (en) | 1997-12-22 | 2005-03-22 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 formulations |
NZ505324A (en) | 1997-12-22 | 2002-11-26 | Human Genome Sciences Inc | Liquid and lyophilised KGF-2 polypeptide formulations used to accelerate soft tissue growth or regeneration |
US6248725B1 (en) | 1999-02-23 | 2001-06-19 | Amgen, Inc. | Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction |
WO2003016505A2 (en) | 2001-08-21 | 2003-02-27 | Chiron Corporation | Kgf polypeptide compositions |
DK1827483T3 (da) | 2004-12-15 | 2014-10-06 | Swedish Orphan Biovitrum Ab Publ | Terapeutiske formuleringer af keratinocyt-vækstfaktor |
KR20230127721A (ko) | 2022-02-25 | 2023-09-01 | 한국해양과학기술원 | 온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69033668T2 (de) * | 1989-01-31 | 2001-04-12 | Jeffrey S Rubin | Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor |
DE69434420D1 (de) * | 1993-09-24 | 2005-08-11 | Wyeth Corp | Strukturelle analoge oberflächenschlaufen der fibroblasten-wachstumsfaktoren |
-
1995
- 1995-10-12 HU HU9901325A patent/HUT78069A/hu unknown
- 1995-10-12 EP EP95938216A patent/EP0785950B1/en not_active Expired - Lifetime
- 1995-10-12 ES ES95938216T patent/ES2196088T3/es not_active Expired - Lifetime
- 1995-10-12 AT AT95938216T patent/ATE237634T1/de active
- 1995-10-12 CA CA002202390A patent/CA2202390C/en not_active Expired - Fee Related
- 1995-10-12 JP JP51337096A patent/JP4422210B2/ja not_active Expired - Fee Related
- 1995-10-12 MX MX9702665A patent/MX9702665A/es not_active IP Right Cessation
- 1995-10-12 DE DE69530404T patent/DE69530404T2/de not_active Expired - Lifetime
- 1995-10-12 PT PT95938216T patent/PT785950E/pt unknown
- 1995-10-12 WO PCT/US1995/013075 patent/WO1996011951A2/en active IP Right Grant
- 1995-10-12 SI SI9530653T patent/SI0785950T1/xx unknown
- 1995-10-12 DK DK95938216T patent/DK0785950T3/da active
- 1995-10-12 AU AU38931/95A patent/AU3893195A/en not_active Abandoned
-
1997
- 1997-04-09 NO NO971621A patent/NO971621L/no unknown
-
2006
- 2006-09-01 JP JP2006237876A patent/JP2007020575A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0785950A2 (en) | 1997-07-30 |
AU3893195A (en) | 1996-05-06 |
EP0785950B1 (en) | 2003-04-16 |
HUT78069A (hu) | 1999-08-30 |
JP2007020575A (ja) | 2007-02-01 |
WO1996011951A3 (en) | 1996-12-12 |
DK0785950T3 (da) | 2003-07-28 |
JP2000511762A (ja) | 2000-09-12 |
DE69530404T2 (de) | 2003-11-13 |
ATE237634T1 (de) | 2003-05-15 |
DE69530404D1 (de) | 2003-05-22 |
CA2202390C (en) | 2005-05-17 |
WO1996011951A2 (en) | 1996-04-25 |
SI0785950T1 (en) | 2003-08-31 |
MX9702665A (es) | 1997-07-31 |
JP4422210B2 (ja) | 2010-02-24 |
NO971621L (no) | 1997-06-12 |
NO971621D0 (no) | 1997-04-09 |
CA2202390A1 (en) | 1996-04-25 |
PT785950E (pt) | 2003-09-30 |
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