ATE81779T1 - Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren. - Google Patents

Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren.

Info

Publication number
ATE81779T1
ATE81779T1 AT86905157T AT86905157T ATE81779T1 AT E81779 T1 ATE81779 T1 AT E81779T1 AT 86905157 T AT86905157 T AT 86905157T AT 86905157 T AT86905157 T AT 86905157T AT E81779 T1 ATE81779 T1 AT E81779T1
Authority
AT
Austria
Prior art keywords
growth factor
pct
peptide analogue
mammals
analogue insulin
Prior art date
Application number
AT86905157T
Other languages
English (en)
Inventor
Francis John Ballard
John Campbell Wallace
Geoffrey Leonard Francis
Christopher James Bagley
Original Assignee
Gropep Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gropep Pty Ltd filed Critical Gropep Pty Ltd
Application granted granted Critical
Publication of ATE81779T1 publication Critical patent/ATE81779T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT86905157T 1985-08-22 1986-08-21 Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren. ATE81779T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPH208185 1985-08-22
EP86905157A EP0235205B1 (de) 1985-08-22 1986-08-21 Peptidanalogedes insulinähnlichen wachstumsfaktors-1 bei säugetieren
PCT/AU1986/000246 WO1987001038A1 (en) 1985-08-22 1986-08-21 Peptide analogues of mammalian insulin-like growth factor-1
CA000583939A CA1341207C (en) 1985-08-22 1988-11-23 Analogues of insulin-like growth factor-1

Publications (1)

Publication Number Publication Date
ATE81779T1 true ATE81779T1 (de) 1992-11-15

Family

ID=25642982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86905157T ATE81779T1 (de) 1985-08-22 1986-08-21 Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren.

Country Status (7)

Country Link
US (1) US5077276A (de)
EP (1) EP0235205B1 (de)
JP (1) JPH0720993B2 (de)
AT (1) ATE81779T1 (de)
AU (1) AU598205B2 (de)
CA (1) CA1341207C (de)
WO (1) WO1987001038A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8505920D0 (sv) * 1985-12-13 1985-12-13 Kabigen Ab New protein and its use
US4963665A (en) * 1986-01-07 1990-10-16 Washington University Human preproinsulin-like growth factor I
US4769361A (en) * 1986-08-07 1988-09-06 International Minerals & Chemical Corp. Method for purifying and isolating two ionic forms of somatomedin C
US4876242A (en) * 1987-09-21 1989-10-24 Merck & Co., Inc. Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast
ATE116335T1 (de) * 1987-12-24 1995-01-15 Gropep Pty Ltd Peptid-analoge vom insulinähnlichen wachstums- faktor 1 (igf-1) oder faktor 2 (igf-2).
US5470828A (en) * 1987-12-24 1995-11-28 Gropep Pty. Ltd. Peptide analogs of insulin-like growth factor II
ATE125869T1 (de) * 1989-06-09 1995-08-15 Gropep Pty Ltd Wachstumshormonfusionsproteine.
US5679771A (en) * 1990-02-13 1997-10-21 Gropep Pty. Ltd. Method for treating intestinal diseases
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
SE9002731D0 (sv) * 1990-08-24 1990-08-24 Kabivitrum Ab Product comprising growth factor
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
US5744139A (en) * 1991-06-28 1998-04-28 University Of Tennessee Research Corporation Insulin-like growth factor I (IGF-1) induced improvement of depressed T4/T8 ratios
US5202119A (en) * 1991-06-28 1993-04-13 Genentech, Inc. Method of stimulating immune response
ES2174838T3 (es) * 1991-10-07 2002-11-16 Brigham & Womens Hospital Metodo para aumentar la absorcion del intestino.
US6310040B1 (en) * 1991-11-08 2001-10-30 Cephalon, Inc. Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
CA2135306A1 (en) * 1992-05-08 1993-11-25 Bradford A. Jameson Igf-1 analogs
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
US5444045A (en) * 1992-09-17 1995-08-22 Gropep, Pty. Ltd. Method of administering IGF-1, IGF-2, and analogs thereof to birds
EP0594492A3 (de) * 1992-10-19 1995-05-10 Takeda Chemical Industries Ltd Wachstumsinhibierender Faktor.
AU1178395A (en) * 1993-11-12 1995-05-29 North Shore University Hospital Research Corporation Method of treating muscular dystrophy
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
JP3501495B2 (ja) * 1994-03-31 2004-03-02 雪印乳業株式会社 ウシインスリン様増殖因子−１含有組成物の製造法
AUPM534794A0 (en) 1994-04-28 1994-05-19 Gropep Pty Ltd Modified milk growth factor
AU3620995A (en) * 1994-09-21 1996-04-09 Chiron Corporation Method of treating hypertension in pregnant mammals
AU4318496A (en) * 1994-12-21 1996-07-10 Auckland Uniservices Limited Enhancement of fetal growth by administration of insulin-likegrowth factor-1(IGF-1)
US5767084A (en) * 1995-10-06 1998-06-16 The Curators Of The University Of Missouri Method of treatment for cystic fibrosis and peptides for same
US5985830A (en) * 1996-09-16 1999-11-16 Dalhousie University Use of IGF-I for the treatment of kidney disorders
US6156728A (en) 1996-11-01 2000-12-05 Genentech, Inc. Treatment of inner ear hair cells
US6593290B1 (en) 1996-11-01 2003-07-15 Genentech, Inc. Treatment of inner ear hair cells
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
DK1141014T3 (da) 1999-01-06 2005-04-11 Genentech Inc Insulinlignende vækstfaktor (IGF) i mutantvariant
JP2002535967A (ja) * 1999-01-06 2002-10-29 ジェネンテック・インコーポレーテッド インシュリン様成長因子（ｉｇｆ）ｉ変異体
ES2208305T3 (es) * 1999-04-08 2004-06-16 Genentech, Inc. Composicion basada en polipeptidos de carga opuesta..
AU2001263215A1 (en) 2000-05-16 2001-11-26 Genentech Inc. Method for treating cartilage disorders
NZ548358A (en) * 2001-02-09 2008-04-30 Genentech Inc Method of identifying agonists of insulin-like growth factor-1
EP1401476A4 (de) * 2001-03-14 2006-03-08 Genentech Inc Igf-antagonistenpeptide
KR101198346B1 (ko) 2003-04-08 2012-11-06 노보 노르디스크 에이/에스 크로마토그래피 고정상의 재생
WO2004089504A1 (en) * 2003-04-08 2004-10-21 Novo Nordisk A/S Regeneration of chromatographic stationary phases
HUE027218T2 (en) * 2003-09-12 2016-10-28 Ipsen Biopharmaceuticals Inc Methods for Treatment of IGF-1 (Insulin-like Growth Factor 1) Deficiency
AU2004278311A1 (en) * 2003-10-03 2005-04-14 Genentech, Inc. IGF binding proteins
EP1791551B1 (de) * 2004-08-30 2020-02-26 Ipsen Biopharmaceuticals, Inc. Verfahren und vorrichtung zur diagnose und behandlung von mangelstörung an insulinähnlichem wachstumsfaktor
US20080103457A1 (en) * 2005-01-11 2008-05-01 Heart Failure Technologies, Inc. University Enterprise Laboratories (Uel) Method and System for Treating Heart Failure
JP2009539805A (ja) 2006-06-09 2009-11-19 ノバルティス アクチエンゲゼルシャフト 安定化されたインスリン様増殖因子ポリペプチド
JP2010523708A (ja) * 2007-04-11 2010-07-15 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリンを投与する方法、関連する組成物および測定方法
RU2372941C2 (ru) * 2007-07-02 2009-11-20 Духовлинов Илья Владимирович Фармацевтическая композиция для генной терапии заболеваний, требующих стимуляции регенераторных процессов, включая повреждения тканей человека различной этиологии, на основе синтетического модифицированного гена инсулиноподобного фактора роста человека первого типа (ифр-1, igf-1)
US20120093775A1 (en) 2009-03-27 2012-04-19 Proyecto De Biomedicina Cima, S.L. Methods and compositions for the treatment of cirrhosis and liver fibrosis
ES2856930T3 (es) * 2015-08-13 2021-09-28 Bernard Stoffel Composición para el tratamiento de afecciones articulares
WO2021005604A1 (en) 2019-07-11 2021-01-14 Opko Biologics Ltd. Long-acting igf-1 or igf-1 variants and methods of producing same
CN110642937B (zh) * 2019-10-11 2021-04-06 南开大学 多肽衍生物、纳米纤维及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
SE8505920D0 (sv) * 1985-12-13 1985-12-13 Kabigen Ab New protein and its use
US4876242A (en) * 1987-09-21 1989-10-24 Merck & Co., Inc. Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast

Also Published As

Publication number Publication date
EP0235205A4 (de) 1989-08-09
EP0235205B1 (de) 1992-10-28
WO1987001038A1 (en) 1987-02-26
AU6286986A (en) 1987-03-10
EP0235205A1 (de) 1987-09-09
CA1341207C (en) 2001-03-20
JPH0720993B2 (ja) 1995-03-08
JPS63501567A (ja) 1988-06-16
US5077276A (en) 1991-12-31
AU598205B2 (en) 1990-06-21

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