DE69133340D1 - Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen - Google Patents

Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen

Info

Publication number
DE69133340D1
DE69133340D1 DE69133340T DE69133340T DE69133340D1 DE 69133340 D1 DE69133340 D1 DE 69133340D1 DE 69133340 T DE69133340 T DE 69133340T DE 69133340 T DE69133340 T DE 69133340T DE 69133340 D1 DE69133340 D1 DE 69133340D1
Authority
DE
Germany
Prior art keywords
pct
interferon
versions
production process
new type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69133340T
Other languages
English (en)
Inventor
Jacques Martal
Eric Degryse
Pierre Gaye
Madia Charlier
Gilles Charpigny
Pierrette Reinaud
Gerard Chaouat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Recherche Agronomique INRA
Original Assignee
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9014945A external-priority patent/FR2669931B1/fr
Priority claimed from FR9014946A external-priority patent/FR2669824B1/fr
Application filed by Institut National de la Recherche Agronomique INRA filed Critical Institut National de la Recherche Agronomique INRA
Application granted granted Critical
Publication of DE69133340D1 publication Critical patent/DE69133340D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69133340T 1990-11-29 1991-11-29 Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen Expired - Lifetime DE69133340D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9014945A FR2669931B1 (fr) 1990-11-29 1990-11-29 Nouveaux variants derives des interferons-alpha et leur procede de production.
FR9014946A FR2669824B1 (fr) 1990-11-29 1990-11-29 Utilisation de variants des interferons alpha pour l'obtention de medicaments.
PCT/FR1991/000953 WO1992009691A1 (fr) 1990-11-29 1991-11-29 Nouveaux variants derives des interferons de type i, leur procede de production, et leurs applications

Publications (1)

Publication Number Publication Date
DE69133340D1 true DE69133340D1 (de) 2003-12-18

Family

ID=26228360

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69133340T Expired - Lifetime DE69133340D1 (de) 1990-11-29 1991-11-29 Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen

Country Status (8)

Country Link
US (1) US5378823A (de)
EP (1) EP0513336B1 (de)
JP (1) JP3366947B2 (de)
AT (1) ATE254179T1 (de)
AU (1) AU656353B2 (de)
CA (1) CA2074802A1 (de)
DE (1) DE69133340D1 (de)
WO (1) WO1992009691A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP1274720A4 (de) 2000-04-12 2004-08-18 Human Genome Sciences Inc Albumin enthaltende fusionsproteine
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
AU2005209926B2 (en) 2004-02-02 2007-09-06 Ambrx, Inc. Modified human four helical bundle polypeptides and their uses
EP2046367A4 (de) 2006-06-07 2009-11-11 Human Genome Sciences Inc Albuminfusionsproteine
CN101939443B (zh) 2008-02-08 2014-01-29 Ambrx公司 经修饰瘦素多肽和其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
PT83613B (en) * 1985-10-28 1988-11-21 Lilly Co Eli Process for the selective chemical removal of a protein amino-terminal residue
US4782139A (en) * 1985-10-28 1988-11-01 Eli Lilly And Company Selective chemical removal of a protein amino-terminal residue
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
EP0400083A1 (de) * 1988-03-18 1990-12-05 Institut National De La Recherche Agronomique (Inra) Trophoblastin-isoformen, durch diese isoformen konstituierte interferone, verfahren zu deren erhalt und deren verwendung
WO1990009806A2 (en) * 1989-03-02 1990-09-07 University Of Florida Composition for the inhibition of tumors and for the non-cytotoxic inhibition of replication of viruses
FR2646437B1 (fr) * 1989-04-28 1991-08-30 Transgene Sa Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant

Also Published As

Publication number Publication date
JPH05504069A (ja) 1993-07-01
JP3366947B2 (ja) 2003-01-14
EP0513336A1 (de) 1992-11-19
WO1992009691A1 (fr) 1992-06-11
US5378823A (en) 1995-01-03
ATE254179T1 (de) 2003-11-15
CA2074802A1 (fr) 1992-05-30
AU656353B2 (en) 1995-02-02
EP0513336B1 (de) 2003-11-12
AU9130591A (en) 1992-06-25

Similar Documents

Publication Publication Date Title
DE69634726D1 (de) Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen
ATE81779T1 (de) Peptidanalogedes insulinaehnlichen wachstumsfaktors-1 bei saeugetieren.
ATE80660T1 (de) Verfahren zur herstellung eines polypeptides.
ATE402957T1 (de) Analoge des menschlichen interferon-alpha mit niedriger toxizität
PL312436A1 (en) Dna structural element encoding yap3 signal peptide
ATE174382T1 (de) Retrovirus aus der hiv-gruppe und dessen verwendung
DE3583824D1 (de) Vorlaeufer des insulins, verfahren zu seiner herstellung und verfahren zur herstellung von humaninsulin aus solchen vorlaeufern des insulins.
DK0477971T3 (da) Humant CNP gen og precursorprotein
DE59101889D1 (de) Variante cd44-oberflächenproteine, diese kodierende dna-sequenzen, antikörper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie.
ATE149523T1 (de) Verfahren zur herstellung von interferon-alpha-2 kristallen
ATE339878T1 (de) Myc-bindende zinkfinger-proteine, ihre herstellung und ihre verwendung
DE69133340D1 (de) Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen
FI942442A0 (fi) Proteiinien tuotto 7B2-proteiinia käyttäen
ATE141616T1 (de) Neue peptide (didemnine), ihre herstellung und verwendung
FI940036A (fi) Nukleotidisekvenssejä ja sykloheksimidiresistenssejä proteiineja
DE69106407T2 (de) Verfahren zur Herstellung von rekombinantem menschlichem gamma-Interferon ohne Cystein und ohne Methionin am N-Terminal.
ATE110779T1 (de) Neue promotorregion.
ATE143974T1 (de) Peptide des hiv-gag proteins, ihre herstellung und verwendung
ATE123056T1 (de) Ancrod-proteine, ihre herstellung und verwendung.
NO974713D0 (no) Gener som koder for lymfocyttinterferon-regulatorisk faktor (LSIRF) polypeptider
DE69534738D1 (de) Leukocyten-aktivierender Faktor
ATE229983T1 (de) Maspin- ein neues serpin mit tumor unterdrückender aktivität
ATE291629T1 (de) Expressionssystem für die sekretion von bioaktivem, menschlichem granulozyt-makrophagem koloniestimulierungsfaktor (gm-csf) und anderen heterologen proteinen aus streptomyces
ATE110775T1 (de) Verfahren zur herstellung von hirudin.
ATE86499T1 (de) Vorbeugende massnahmen zur verhinderung der ''komplexen respiratorischen erkrankung bei rindern'' durch verabreichung von interferon.

Legal Events

Date Code Title Description
8332 No legal effect for de