ATE254179T1 - Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen - Google Patents

Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen

Info

Publication number
ATE254179T1
ATE254179T1 AT92902218T AT92902218T ATE254179T1 AT E254179 T1 ATE254179 T1 AT E254179T1 AT 92902218 T AT92902218 T AT 92902218T AT 92902218 T AT92902218 T AT 92902218T AT E254179 T1 ATE254179 T1 AT E254179T1
Authority
AT
Austria
Prior art keywords
pct
new type
production processes
production
variants
Prior art date
Application number
AT92902218T
Other languages
English (en)
Inventor
Jacques Martal
Eric Degryse
Pierre Gaye
Madia Charlier
Gilles Charpigny
Pierrette Reinaud
Gerard Chaouat
Original Assignee
Agronomique Inst Nat Rech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9014946A external-priority patent/FR2669824B1/fr
Priority claimed from FR9014945A external-priority patent/FR2669931B1/fr
Application filed by Agronomique Inst Nat Rech filed Critical Agronomique Inst Nat Rech
Application granted granted Critical
Publication of ATE254179T1 publication Critical patent/ATE254179T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Peptides Or Proteins (AREA)
AT92902218T 1990-11-29 1991-11-29 Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen ATE254179T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9014946A FR2669824B1 (fr) 1990-11-29 1990-11-29 Utilisation de variants des interferons alpha pour l'obtention de medicaments.
FR9014945A FR2669931B1 (fr) 1990-11-29 1990-11-29 Nouveaux variants derives des interferons-alpha et leur procede de production.
PCT/FR1991/000953 WO1992009691A1 (fr) 1990-11-29 1991-11-29 Nouveaux variants derives des interferons de type i, leur procede de production, et leurs applications

Publications (1)

Publication Number Publication Date
ATE254179T1 true ATE254179T1 (de) 2003-11-15

Family

ID=26228360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92902218T ATE254179T1 (de) 1990-11-29 1991-11-29 Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen

Country Status (8)

Country Link
US (1) US5378823A (de)
EP (1) EP0513336B1 (de)
JP (1) JP3366947B2 (de)
AT (1) ATE254179T1 (de)
AU (1) AU656353B2 (de)
CA (1) CA2074802A1 (de)
DE (1) DE69133340D1 (de)
WO (1) WO1992009691A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JP2003530838A (ja) 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
US8778880B2 (en) * 2004-02-02 2014-07-15 Ambrx, Inc. Human growth hormone modified at position 35
BRPI0712383A2 (pt) * 2006-06-07 2012-07-10 Human Genome Sciences Inc proteìnas de fusão da albumina
US9938333B2 (en) 2008-02-08 2018-04-10 Ambrx, Inc. Modified leptin polypeptides and their uses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
PT83613B (en) * 1985-10-28 1988-11-21 Lilly Co Eli Process for the selective chemical removal of a protein amino-terminal residue
US4782139A (en) * 1985-10-28 1988-11-01 Eli Lilly And Company Selective chemical removal of a protein amino-terminal residue
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
AU638207B2 (en) * 1988-03-18 1993-06-24 Institut National De La Recherche Agronomique (Inra) Isoforms of trophoblastine
WO1990009806A2 (en) * 1989-03-02 1990-09-07 University Of Florida Composition for the inhibition of tumors and for the non-cytotoxic inhibition of replication of viruses
FR2646437B1 (fr) * 1989-04-28 1991-08-30 Transgene Sa Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant

Also Published As

Publication number Publication date
JP3366947B2 (ja) 2003-01-14
AU656353B2 (en) 1995-02-02
AU9130591A (en) 1992-06-25
EP0513336B1 (de) 2003-11-12
US5378823A (en) 1995-01-03
WO1992009691A1 (fr) 1992-06-11
DE69133340D1 (de) 2003-12-18
CA2074802A1 (fr) 1992-05-30
JPH05504069A (ja) 1993-07-01
EP0513336A1 (de) 1992-11-19

Similar Documents

Publication Publication Date Title
ES2165881T3 (es) Constructo de adn que codifica el peptido señal yap3.
DE69839812D1 (de) Analoge des menschlichen interferon-alpha mit niedriger toxizität
EP0897987A3 (de) Sekretion vom mit Gamma-Interferon Signalpeptid gebundenen humänen Protein
DE69634726D1 (de) Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen
DE59309207D1 (de) Retrovirus aus der HIV-Gruppe und dessen Verwendung
ATE162532T1 (de) Merschliches cnp-gen und vorläufer protein
ATE171474T1 (de) Hochstabile rekombinante hefen für die herstellung von rekombinanten proteinen
DE59101889D1 (de) Variante cd44-oberflächenproteine, diese kodierende dna-sequenzen, antikörper gegen diese proteine sowie ihre verwendung in der diagnostik und therapie.
AU4554985A (en) Improvements in or relating to interferons
ATE248918T1 (de) Rekombinante dnase b aus streptococcus pyogenes
ATE339878T1 (de) Myc-bindende zinkfinger-proteine, ihre herstellung und ihre verwendung
ATE254179T1 (de) Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen
ATE141616T1 (de) Neue peptide (didemnine), ihre herstellung und verwendung
MX9706735A (es) Citocinas aviares novedosas y secuencias geneticas que codifican las mismas.
DE69106407D1 (de) Verfahren zur Herstellung von rekombinantem menschlichem gamma-Interferon ohne Cystein und ohne Methionin am N-Terminal.
TR199901190T2 (xx) Interferon-(alfa) N�kleik asitlerinin verilmesi ve sentezlenmesi i�in y�ntemler ve bile�imler.
ATE216706T1 (de) Peptide des hiv-gag proteins, ihre herstellung und verwendung
NO974713D0 (no) Gener som koder for lymfocyttinterferon-regulatorisk faktor (LSIRF) polypeptider
DE69534738D1 (de) Leukocyten-aktivierender Faktor
ES2061585T3 (es) Señal de secrecion de bar1.
DE58909261D1 (de) Ancrod-proteine, ihre herstellung und verwendung.
ATE229983T1 (de) Maspin- ein neues serpin mit tumor unterdrückender aktivität
ATE291629T1 (de) Expressionssystem für die sekretion von bioaktivem, menschlichem granulozyt-makrophagem koloniestimulierungsfaktor (gm-csf) und anderen heterologen proteinen aus streptomyces
ATE161046T1 (de) Neues thrombininhibitorisches protein aus zecken
ATE86499T1 (de) Vorbeugende massnahmen zur verhinderung der ''komplexen respiratorischen erkrankung bei rindern'' durch verabreichung von interferon.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties