ATE203913T1 - Eine gelpräparation aus vernetzter gelatine, die einen basischen wachstumsfaktor für fibroblasten enthält - Google Patents
Eine gelpräparation aus vernetzter gelatine, die einen basischen wachstumsfaktor für fibroblasten enthältInfo
- Publication number
- ATE203913T1 ATE203913T1 AT94916430T AT94916430T ATE203913T1 AT E203913 T1 ATE203913 T1 AT E203913T1 AT 94916430 T AT94916430 T AT 94916430T AT 94916430 T AT94916430 T AT 94916430T AT E203913 T1 ATE203913 T1 AT E203913T1
- Authority
- AT
- Austria
- Prior art keywords
- cross
- growth factor
- linked gelatin
- fibroblasts
- gel preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15274993 | 1993-05-31 | ||
PCT/JP1994/000876 WO1994027630A1 (fr) | 1993-05-31 | 1994-05-31 | Preparation de gel a base de gelatine reticulee contenant un facteur de croissance de fibroblaste de base |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE203913T1 true ATE203913T1 (de) | 2001-08-15 |
Family
ID=15547330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94916430T ATE203913T1 (de) | 1993-05-31 | 1994-05-31 | Eine gelpräparation aus vernetzter gelatine, die einen basischen wachstumsfaktor für fibroblasten enthält |
Country Status (6)
Country | Link |
---|---|
US (1) | US6831058B1 (de) |
EP (1) | EP0702959B1 (de) |
JP (1) | JP3639593B2 (de) |
AT (1) | ATE203913T1 (de) |
DE (1) | DE69427908T2 (de) |
WO (1) | WO1994027630A1 (de) |
Families Citing this family (68)
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US7435425B2 (en) | 2001-07-17 | 2008-10-14 | Baxter International, Inc. | Dry hemostatic compositions and methods for their preparation |
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JP2011046749A (ja) * | 1996-08-27 | 2011-03-10 | Baxter Internatl Inc | 癒着防止用の断片化重合体ヒドロゲルおよびそれらの調製 |
US6066325A (en) | 1996-08-27 | 2000-05-23 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
US8603511B2 (en) | 1996-08-27 | 2013-12-10 | Baxter International, Inc. | Fragmented polymeric compositions and methods for their use |
AU736784B2 (en) * | 1997-06-03 | 2001-08-02 | Celltran Limited | New medicaments based on polymers composed of methacrylamide-modified gelatin |
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JP2003238439A (ja) * | 2002-02-13 | 2003-08-27 | Yasuhiko Tabata | 虚血治療剤 |
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US7927626B2 (en) | 2003-08-07 | 2011-04-19 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
JP4532092B2 (ja) * | 2003-09-30 | 2010-08-25 | 泰彦 田畑 | 血管新生剤 |
CA2542041C (en) * | 2003-10-10 | 2014-12-09 | Cellular Bioengineering, Inc. | Methods and compositions for growing corneal endothelial and related cells on biopolymers and creation of artifical corneal transplants |
JP2005218780A (ja) * | 2004-02-09 | 2005-08-18 | Menicon Co Ltd | 薬物放出速度を制御し得る薬物徐放可能なヒドロゲル材料の製造方法 |
WO2005087257A1 (ja) * | 2004-03-16 | 2005-09-22 | Kaken Pharmaceutical Co., Ltd. | 架橋ゼラチンゲルを担体とする軟骨組織修復治療剤 |
JPWO2005097166A1 (ja) * | 2004-04-09 | 2008-02-28 | 二郎 中村 | ゼラチンゲルを担体とする糖尿病性神経障害治療剤 |
JP2005325075A (ja) * | 2004-05-14 | 2005-11-24 | Yasuhiko Tabata | 架橋ゼラチンゲルを担体とする半月板損傷治療剤 |
JP4685090B2 (ja) * | 2005-02-14 | 2011-05-18 | 株式会社メドジェル | 医療用ハイドロゲル |
EP1952821B1 (de) * | 2005-10-19 | 2013-02-20 | Osaka University | Therapeutisches mittel zur regeneration des dentin-pulpa-komplexes |
US20070154546A1 (en) * | 2005-12-30 | 2007-07-05 | Zhang Jack Y | Sustained release pharmaceutical compositions |
AU2007267338B2 (en) | 2006-05-31 | 2013-04-04 | Baxter Healthcare S.A. | Method for directed cell in-growth and controlled tissue regeneration in spinal surgery |
EP2052740A4 (de) * | 2006-08-01 | 2009-11-11 | Nichiban Kk | Vernetzte mehrschichtige gelatinegelstruktur, träger für einen bioaktiven faktor, zubereitung zur freisetzung des bioaktiven faktors und herstellungsverfahren dafür |
TWI436793B (zh) | 2006-08-02 | 2014-05-11 | Baxter Int | 快速作用之乾密封膠及其使用和製造方法 |
WO2008047904A1 (fr) * | 2006-10-20 | 2008-04-24 | National University Corporation Nagoya University | Agent thérapeutique pour vasculopathie périphérique oblitérante et utilisation |
JPWO2008072379A1 (ja) * | 2006-12-13 | 2010-03-25 | 富士フイルム株式会社 | 修飾された生体高分子の製造方法及び生体高分子の架橋方法 |
JP5047603B2 (ja) * | 2006-12-15 | 2012-10-10 | エア・ウォーター株式会社 | ゼラチン成形物およびその製造方法 |
EP1961414A1 (de) * | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung |
EP1961411A1 (de) * | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Zusammensetzung mit gesteuerter Freisetzung |
EP2121749B1 (de) | 2007-02-21 | 2013-07-03 | FUJIFILM Manufacturing Europe B.V. | Rekombinante gelatinen |
DE102007051059B4 (de) * | 2007-10-18 | 2014-04-03 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Bioverbundmaterial für die kontrollierte Freisetzung von Wirkstoffen |
US8790698B2 (en) | 2007-10-30 | 2014-07-29 | Baxter International Inc. | Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects |
EP2218459B1 (de) | 2007-11-07 | 2012-02-01 | Ono Pharmaceutical Co., Ltd. | Sdf-1 enthaltende zusammensetzung mit anhaltender freisetzung |
JP5569398B2 (ja) | 2008-02-29 | 2014-08-13 | フェッローサン メディカル ディバイス エー/エス | 止血および/または創傷治癒を促進するための装置 |
JP5351183B2 (ja) * | 2009-02-05 | 2013-11-27 | ニチバン株式会社 | 照射架橋水溶性高分子粒子及び照射架橋ゼラチン粒子の製造方法 |
EP2428215B1 (de) * | 2009-05-07 | 2017-10-18 | FUJIFILM Corporation | Rekombinante Gelatine zur Verwendung in der Behandlung von ischämischen und Herzerkrankungen und anderen |
US9039783B2 (en) | 2009-05-18 | 2015-05-26 | Baxter International, Inc. | Method for the improvement of mesh implant biocompatibility |
AU2010262058B2 (en) | 2009-06-16 | 2013-08-29 | Baxter Healthcare S.A. | Hemostatic sponge |
WO2011010399A1 (ja) * | 2009-07-24 | 2011-01-27 | 千寿製薬株式会社 | 角膜内皮細胞増殖促進剤 |
WO2011052089A1 (ja) * | 2009-11-02 | 2011-05-05 | ニチバン株式会社 | 電離性放射線で架橋したヒドロゲルから成る生体内薬剤徐放用担体材料及びその製造方法 |
CN102597230A (zh) * | 2009-11-13 | 2012-07-18 | 株式会社日立高新技术 | 含有粒子的细胞聚集体 |
JP2013514093A (ja) | 2009-12-16 | 2013-04-25 | バクスター・インターナショナル・インコーポレイテッド | 止血スポンジ |
SA111320355B1 (ar) | 2010-04-07 | 2015-01-08 | Baxter Heathcare S A | إسفنجة لايقاف النزف |
WO2011151386A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
ES2682302T3 (es) | 2010-06-01 | 2018-09-19 | Baxter International Inc | Proceso para la producción de composiciones hemostáticas secas y estables |
MX344402B (es) | 2010-06-01 | 2016-12-14 | Baxter Int Inc * | Proceso para elaborar composiciones hemostaticas secas y estables. |
MX356185B (es) | 2011-10-11 | 2018-05-17 | Baxter Int | Composiciones hemostaticas. |
EP2766058B1 (de) | 2011-10-11 | 2022-11-23 | Baxter International Inc. | Hämostatische zusammensetzungen |
CN103889447B (zh) | 2011-10-27 | 2015-11-25 | 巴克斯特国际公司 | 止血组合物 |
RU2657955C2 (ru) | 2012-03-06 | 2018-06-18 | Ферросан Медикал Дивайсиз А/С | Контейнер под давлением, содержащий гемостатическую пасту |
CA2874290C (en) | 2012-06-12 | 2020-02-25 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US9347037B2 (en) * | 2013-02-11 | 2016-05-24 | Evan Masataka Masutani | Methods and apparatus for building complex 3D scaffolds and biomimetic scaffolds built therefrom |
JP6339062B2 (ja) * | 2013-02-15 | 2018-06-06 | 国立大学法人高知大学 | ハイドロゲルを担体として過酸化水素を徐放する腫瘍内局注用の放射線/化学療法増感剤 |
WO2014202760A2 (en) | 2013-06-21 | 2014-12-24 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
EP3079731B1 (de) | 2013-12-11 | 2018-08-08 | Ferrosan Medical Devices A/S | Trockenzusammensetzung mit extrusionsverstärker |
CA2960309A1 (en) | 2014-10-13 | 2016-04-21 | Ferrosan Medical Devices A/S | Dry composition for use in haemostasis and wound healing |
RU2705905C2 (ru) | 2014-12-24 | 2019-11-12 | Ферросан Медикал Дивайсиз А/С | Шприц для удерживания и смешивания первого и второго веществ |
BR112017027695A2 (pt) | 2015-07-03 | 2018-09-04 | Ferrosan Medical Devices As | seringa para retenção e mistura de primeira e segunda substâncias |
CN108495709B (zh) * | 2016-01-25 | 2021-09-03 | 三得利控股株式会社 | 含有功能性物质的胶囊及其制造方法 |
CN109069654A (zh) * | 2016-03-28 | 2018-12-21 | 富士胶片株式会社 | 制剂、制剂用部件及它们的制造方法 |
CN112368028A (zh) | 2018-05-09 | 2021-02-12 | 弗罗桑医疗设备公司 | 用于制备止血组合物的方法 |
JP2023015416A (ja) * | 2019-12-27 | 2023-02-01 | Eaファーマ株式会社 | 瘻孔治療用材料 |
Family Cites Families (20)
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---|---|---|---|---|
US3923969A (en) * | 1973-06-12 | 1975-12-02 | Battelle Institut E V | Carrier system for a drug with sustained release |
US4785079A (en) * | 1984-11-09 | 1988-11-15 | The Salk Institute For Biological Studies | Isolation of fibroblast growth factor |
MX163953B (es) * | 1984-03-27 | 1992-07-03 | Univ New Jersey Med | Procedimiento para preparar una matriz biodegradable a base de colageno |
JPH0759522B2 (ja) * | 1985-12-27 | 1995-06-28 | 住友製薬株式会社 | 徐放性製剤の製造法 |
JP2587219B2 (ja) * | 1986-06-10 | 1997-03-05 | エーザイ株式会社 | 溶解遅延性のゼラチン製剤組成物 |
NZ226171A (en) * | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
US5164410A (en) * | 1988-01-09 | 1992-11-17 | Takeda Chemical Industries, Ltd. | Fumagillol derivatives and pharmaceutical compositions thereof |
JPH01282394A (ja) | 1988-05-10 | 1989-11-14 | Toshiba Corp | 電動機の張力制御装置 |
US4950483A (en) * | 1988-06-30 | 1990-08-21 | Collagen Corporation | Collagen wound healing matrices and process for their production |
JPH0249734A (ja) * | 1988-08-12 | 1990-02-20 | Wakunaga Pharmaceut Co Ltd | 新規組成物 |
US5202311A (en) * | 1988-08-19 | 1993-04-13 | Children's Medical Center Corporation | Stabilized fgf composition |
US5298243A (en) * | 1988-10-20 | 1994-03-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Colony stimulating factor-gelatin conjugate |
US5162430A (en) * | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
CA2020654A1 (en) * | 1989-07-07 | 1991-01-08 | Yohko Akiyama | Stabilized fgf composition and production thereof |
GB9014871D0 (en) * | 1990-07-05 | 1990-08-22 | Erba Carlo Spa | Drug delivery system for administering growth factor |
JP3135138B2 (ja) * | 1990-12-19 | 2001-02-13 | 科研製薬株式会社 | 骨疾患治療剤 |
JPH05132426A (ja) * | 1991-02-15 | 1993-05-28 | Takeda Chem Ind Ltd | 骨組織の形成促進剤 |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
US5656598A (en) * | 1994-03-08 | 1997-08-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Use of fibroblast growth factors to stimulate bone growth |
WO1995024211A1 (en) * | 1994-03-08 | 1995-09-14 | Osteosa, Inc. | Use of fibroblast growth factors to stimulate bone growth |
-
1994
- 1994-05-31 WO PCT/JP1994/000876 patent/WO1994027630A1/ja active IP Right Grant
- 1994-05-31 JP JP50048195A patent/JP3639593B2/ja not_active Expired - Lifetime
- 1994-05-31 DE DE69427908T patent/DE69427908T2/de not_active Expired - Lifetime
- 1994-05-31 EP EP94916430A patent/EP0702959B1/de not_active Expired - Lifetime
- 1994-05-31 AT AT94916430T patent/ATE203913T1/de not_active IP Right Cessation
-
1995
- 1995-11-30 US US08/567,355 patent/US6831058B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1994027630A1 (fr) | 1994-12-08 |
US6831058B1 (en) | 2004-12-14 |
EP0702959B1 (de) | 2001-08-08 |
EP0702959A1 (de) | 1996-03-27 |
DE69427908T2 (de) | 2001-11-22 |
DE69427908D1 (de) | 2001-09-13 |
EP0702959A4 (de) | 1996-11-27 |
JP3639593B2 (ja) | 2005-04-20 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |