MX347770B - Compuesto para el tratamiento de alteraciones neuropsiquiatricas. - Google Patents

Compuesto para el tratamiento de alteraciones neuropsiquiatricas.

Info

Publication number
MX347770B
MX347770B MX2013012130A MX2013012130A MX347770B MX 347770 B MX347770 B MX 347770B MX 2013012130 A MX2013012130 A MX 2013012130A MX 2013012130 A MX2013012130 A MX 2013012130A MX 347770 B MX347770 B MX 347770B
Authority
MX
Mexico
Prior art keywords
compounds
treatment
neuropsychiatric disorders
symptoms
digestive enzymes
Prior art date
Application number
MX2013012130A
Other languages
English (en)
Other versions
MX2013012130A (es
Inventor
Joan M Fallon
Matthew Heil
James F Szigethy
James J Fallon
Original Assignee
Curemark Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curemark Llc filed Critical Curemark Llc
Publication of MX2013012130A publication Critical patent/MX2013012130A/es
Publication of MX347770B publication Critical patent/MX347770B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere al uso de una composición que comprende enzimas digestivas para preparar un medicamento para tratar esquizofrenia, en donde las enzimas digestivas comprenden una proteasa, una milasa y una lipasa. En donde el individuo que tiene esquizofrenia exhibe uno o más síntomas seleccionados del grupo que consiste en uno o más síntomas positivos, uno o más síntomas negativos, uno o más síntomas de deterioro cognoscitivo y una combinación de los mismos.
MX2013012130A 2011-04-21 2012-04-20 Compuesto para el tratamiento de alteraciones neuropsiquiatricas. MX347770B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161477988P 2011-04-21 2011-04-21
PCT/US2012/034489 WO2012145651A2 (en) 2011-04-21 2012-04-20 Compounds for the treatment of neuropsychiatric disorders

Publications (2)

Publication Number Publication Date
MX2013012130A MX2013012130A (es) 2014-02-27
MX347770B true MX347770B (es) 2017-05-12

Family

ID=47042184

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013012130A MX347770B (es) 2011-04-21 2012-04-20 Compuesto para el tratamiento de alteraciones neuropsiquiatricas.
MX2017006158A MX362974B (es) 2011-04-21 2012-04-20 Compuestos para el tratamiento de alteraciones neuropsiquiatricas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2017006158A MX362974B (es) 2011-04-21 2012-04-20 Compuestos para el tratamiento de alteraciones neuropsiquiatricas.

Country Status (13)

Country Link
US (6) US8980252B2 (es)
EP (2) EP2701733B1 (es)
JP (2) JP5976100B2 (es)
CN (2) CN106310242B (es)
AU (2) AU2012245287B2 (es)
BR (1) BR112013027034A8 (es)
CA (1) CA2837134C (es)
DK (2) DK3305317T3 (es)
ES (2) ES2804223T3 (es)
GB (1) GB2503852B (es)
HU (1) HUE050873T2 (es)
MX (2) MX347770B (es)
WO (1) WO2012145651A2 (es)

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US20070053895A1 (en) 2000-08-14 2007-03-08 Fallon Joan M Method of treating and diagnosing parkinsons disease and related dysautonomic disorders
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
EP2318035B1 (en) 2008-07-01 2019-06-12 Curemark, Llc Methods and compositions for the treatment of symptoms of neurological and mental health disorders
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
ES2668909T3 (es) 2009-01-06 2018-05-23 Galenagen, Llc Composiciones que comprenden proteasa, amilasa y lipasa para su uso en el tratamiento de infecciones por Staphylococcus aureus
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US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
US9511125B2 (en) 2009-10-21 2016-12-06 Curemark Llc Methods and compositions for the treatment of influenza
CN106310242B (zh) * 2011-04-21 2020-02-28 柯尔马克有限责任公司 用于治疗神经精神障碍的化合物
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
WO2018191233A1 (en) * 2017-04-10 2018-10-18 Curemark, Llc Compositions for treating addiction
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US11541009B2 (en) 2020-09-10 2023-01-03 Curemark, Llc Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
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AU2017203919B2 (en) 2019-08-29
JP5976100B2 (ja) 2016-08-23
CN103619348A (zh) 2014-03-05
WO2012145651A3 (en) 2013-01-17
GB2503852B (en) 2018-12-12
US10279016B2 (en) 2019-05-07
US8980252B2 (en) 2015-03-17
DK2701733T3 (da) 2019-05-27
CN106310242B (zh) 2020-02-28
EP2701733A4 (en) 2014-12-31
AU2017203919A1 (en) 2017-06-29
JP2014512390A (ja) 2014-05-22
AU2012245287A1 (en) 2013-11-07
BR112013027034A2 (pt) 2016-09-06
US9492515B2 (en) 2016-11-15
US20140127184A1 (en) 2014-05-08
CN103619348B (zh) 2016-10-26
WO2012145651A2 (en) 2012-10-26
JP6404278B2 (ja) 2018-10-10
ES2804223T3 (es) 2021-02-04
HK1250640A1 (en) 2019-01-11
US20210145947A1 (en) 2021-05-20
AU2012245287B2 (en) 2017-04-13
EP3305317B1 (en) 2020-06-24
BR112013027034A8 (pt) 2018-01-02
CA2837134C (en) 2019-04-02
HUE050873T2 (hu) 2021-01-28
JP2016216494A (ja) 2016-12-22
US20240156924A1 (en) 2024-05-16
CN106310242A (zh) 2017-01-11
MX362974B (es) 2019-02-28
MX2013012130A (es) 2014-02-27
US10940187B2 (en) 2021-03-09
ES2726978T3 (es) 2019-10-11
GB2503852A (en) 2014-01-08
EP2701733B1 (en) 2019-04-03
EP3305317A1 (en) 2018-04-11
US20170189501A1 (en) 2017-07-06

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