MX339812B - Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa. - Google Patents
Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa.Info
- Publication number
- MX339812B MX339812B MX2012003219A MX2012003219A MX339812B MX 339812 B MX339812 B MX 339812B MX 2012003219 A MX2012003219 A MX 2012003219A MX 2012003219 A MX2012003219 A MX 2012003219A MX 339812 B MX339812 B MX 339812B
- Authority
- MX
- Mexico
- Prior art keywords
- organisms
- pufas
- fatty acid
- express
- nucleic acid
- Prior art date
Links
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title abstract 7
- 108010030975 Polyketide Synthases Proteins 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000057234 Acyl transferases Human genes 0.000 abstract 2
- 108700016155 Acyl transferases Proteins 0.000 abstract 2
- 102100022089 Acyl-[acyl-carrier-protein] hydrolase Human genes 0.000 abstract 2
- 102000005870 Coenzyme A Ligases Human genes 0.000 abstract 2
- 108010039731 Fatty Acid Synthases Proteins 0.000 abstract 2
- 108010011449 Long-chain-fatty-acid-CoA ligase Proteins 0.000 abstract 2
- LTYOQGRJFJAKNA-KKIMTKSISA-N Malonyl CoA Natural products S(C(=O)CC(=O)O)CCNC(=O)CCNC(=O)[C@@H](O)C(CO[P@](=O)(O[P@](=O)(OC[C@H]1[C@@H](OP(=O)(O)O)[C@@H](O)[C@@H](n2c3ncnc(N)c3nc2)O1)O)O)(C)C LTYOQGRJFJAKNA-KKIMTKSISA-N 0.000 abstract 2
- 235000003869 genetically modified organism Nutrition 0.000 abstract 2
- LTYOQGRJFJAKNA-DVVLENMVSA-N malonyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 LTYOQGRJFJAKNA-DVVLENMVSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 239000003921 oil Substances 0.000 abstract 2
- 108700014220 acyltransferase activity proteins Proteins 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78320506P | 2006-03-15 | 2006-03-15 | |
| US78461606P | 2006-03-21 | 2006-03-21 | |
| PCT/US2007/064104 WO2007106903A2 (en) | 2006-03-15 | 2007-03-15 | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX339812B true MX339812B (es) | 2016-06-08 |
Family
ID=38510298
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012003219A MX339812B (es) | 2006-03-15 | 2007-03-15 | Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa. |
| MX2008011783A MX340759B (es) | 2006-03-15 | 2007-03-15 | Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados. |
| MX2008011784A MX2008011784A (es) | 2006-03-15 | 2007-03-15 | Produccion de ácido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policétido pufa. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008011783A MX340759B (es) | 2006-03-15 | 2007-03-15 | Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados. |
| MX2008011784A MX2008011784A (es) | 2006-03-15 | 2007-03-15 | Produccion de ácido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policétido pufa. |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US7759548B2 (OSRAM) |
| EP (3) | EP2653557A1 (OSRAM) |
| JP (4) | JP5227302B2 (OSRAM) |
| KR (3) | KR101506347B1 (OSRAM) |
| CN (1) | CN104073505A (OSRAM) |
| AU (2) | AU2007226510B2 (OSRAM) |
| BR (1) | BRPI0709317A2 (OSRAM) |
| CA (2) | CA2646317A1 (OSRAM) |
| ES (1) | ES2527875T3 (OSRAM) |
| IL (2) | IL194078A (OSRAM) |
| MX (3) | MX339812B (OSRAM) |
| TW (2) | TWI504748B (OSRAM) |
| WO (3) | WO2007106905A2 (OSRAM) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US7211418B2 (en) | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| TWI350854B (en) | 2001-04-16 | 2011-10-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7807849B2 (en) | 2004-04-22 | 2010-10-05 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| CA3023314C (en) | 2004-04-22 | 2019-12-10 | Commonwealth Scientific And Industrial Research Organisation | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| US7759548B2 (en) * | 2006-03-15 | 2010-07-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems |
| RU2009111266A (ru) | 2006-08-29 | 2010-10-10 | Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) | Синтез жирных кислот |
| CN101903513B (zh) * | 2007-01-12 | 2013-08-21 | 科罗拉多大学董事会法人 | 增强微生物对产生的有机化学物质的耐受性的组合物和方法 |
| KR101504618B1 (ko) | 2007-06-01 | 2015-03-23 | 솔라짐, 인코포레이티드 | 미생물에서 오일의 생성 |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| WO2009097331A1 (en) * | 2008-01-28 | 2009-08-06 | The Board Of Regents Of The University Of Oklahoma | Very long chain polyunsaturated fatty acids, methods of production, and uses |
| WO2010019813A2 (en) * | 2008-08-13 | 2010-02-18 | Sapphire Energy, Inc. | Production of fatty actds by genetically modified photosynthetic organisms |
| US20110218354A1 (en) * | 2008-09-19 | 2011-09-08 | President And Fellows Of Harvard College | Photoautotrophic Adipogenesis Technology (Phat) |
| ES2644883T3 (es) | 2008-11-18 | 2017-11-30 | Commonwealth Scientific And Industrial Research Organisation | Enzimas y métodos para producir ácidos grasos omega-3 |
| ES2583639T3 (es) | 2008-11-28 | 2016-09-21 | Terravia Holdings, Inc. | Producción de aceites específicos en microorganismos heterótrofos |
| CN102325874A (zh) * | 2008-12-19 | 2012-01-18 | α-J研究有限合伙公司 | 通过使细胞增殖与海藻产品生产分离来最优化海藻产品的生产 |
| TW201028472A (en) * | 2009-01-13 | 2010-08-01 | Alpha J Res Ltd Partnership | Use of plant growth regulators to enhance algae growth for the production of added value products |
| CA2755667C (en) * | 2009-03-16 | 2018-06-12 | Martek Biosciences Corporation | Protein production in microorganisms of the phylum labyrinthulomycota |
| ES2717102T3 (es) | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| JP2012529277A (ja) * | 2009-06-08 | 2012-11-22 | ロザムステッド リサーチ リミテッド | 新規の脂肪酸伸長成分およびその使用 |
| BRPI1009593A2 (pt) * | 2009-06-30 | 2015-08-18 | Solae Llc | Composição alimentícia e método de utilização do óleo de soja enriquecido com das" |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| CN102695799A (zh) | 2009-09-27 | 2012-09-26 | Opx生物工艺学公司 | 用于制备3-羟基丙酸和其它产物的方法 |
| US9012197B2 (en) * | 2009-12-28 | 2015-04-21 | Merial, Inc. | Production of hemagglutinin-neuraminidase protein in microalgae |
| EP4130273B1 (en) * | 2009-12-28 | 2024-06-12 | Sanofi Vaccine Technologies, S.A.S. | Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof |
| PE20130491A1 (es) | 2009-12-30 | 2013-05-02 | Basf Pharma Callanish Ltd | Proceso simulado de separacion cromatografica de lecho movil para la purificacion de acidos grasos poliinsaturados |
| AR079852A1 (es) * | 2010-01-07 | 2012-02-22 | Aedenswil Basf Agro B V Arnhem Nl Zweigniederlassung W | Plantas tolerantes a herbicidas |
| MX2012008700A (es) * | 2010-01-27 | 2012-10-05 | Univ Colorado Regents | Reduccion con microorganismos de productos quimicos de alto valor y composiciones, metodos y sistemas relacionados. |
| KR101758591B1 (ko) * | 2010-02-01 | 2017-07-14 | 산토리 홀딩스 가부시키가이샤 | 아실-CoA 신세타제 호몰로그를 코딩하는 폴리뉴클레오타이드 및 그 용도 |
| US8372465B2 (en) | 2010-02-17 | 2013-02-12 | Bunge Oils, Inc. | Oil compositions of stearidonic acid |
| TW201144442A (en) * | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
| US11236351B2 (en) * | 2010-05-17 | 2022-02-01 | Dow Agrosciences Llc | Production of DHA and other LC PUFAs in plants |
| SG10201504187YA (en) | 2010-05-28 | 2015-06-29 | Solazyme Inc | Tailored oils produced from recombinant heterotrophic microorganisms |
| AU2013202057B2 (en) * | 2010-06-25 | 2016-01-28 | Basf Plant Science Company Gmbh | Acyltransferases and uses therof in fatty acid production |
| EP2585603B1 (en) | 2010-06-25 | 2017-12-20 | BASF Plant Science Company GmbH | Acyltransferases and uses therof in fatty acid production |
| CA3024641A1 (en) | 2010-11-03 | 2012-05-10 | Corbion Biotech, Inc. | Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods |
| JP6071904B2 (ja) | 2011-02-02 | 2017-02-01 | テラヴィア ホールディングス, インコーポレイテッド | 組み換え油産生微生物から生成される用途に応じた油 |
| CN102250864B (zh) * | 2011-05-03 | 2013-03-20 | 中国农业大学 | 亚油酸异构酶在脱氢和异构方面的双重用途 |
| AU2012253803A1 (en) | 2011-05-06 | 2013-12-05 | Terravia Holdings, Inc. | Genetically engineered microorganisms that metabolize xylose |
| GB201111595D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | Improved process |
| GB201111594D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | New improved process |
| TW201307553A (zh) * | 2011-07-26 | 2013-02-16 | Dow Agrosciences Llc | 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術 |
| BR112014002418A2 (pt) * | 2011-08-04 | 2017-03-14 | Suntory Holdings Ltd | proteína tendo atividade para promover alongamento da cadeia de ácido graxo, gene que codifica a mesma e seu uso |
| WO2013077420A1 (ja) * | 2011-11-25 | 2013-05-30 | 独立行政法人農業生物資源研究所 | 植物の形質転換体、植物の形質転換方法、並びに該方法に用いられるベクター |
| JP6499577B2 (ja) | 2012-04-18 | 2019-04-10 | テラヴィア ホールディングス, インコーポレイテッド | 調整油 |
| US9719114B2 (en) | 2012-04-18 | 2017-08-01 | Terravia Holdings, Inc. | Tailored oils |
| DE102012207921A1 (de) | 2012-05-11 | 2013-11-14 | Evonik Industries Ag | Mehrstufiges Syntheseverfahren mit Synthesegas |
| CA3082388A1 (en) | 2012-06-15 | 2013-12-19 | Commonwealth Scientific And Industrial Research Organisation | Genetic constructs for producing long chain polyunsaturated fatty acids in plant cells |
| US20140051136A1 (en) * | 2012-08-10 | 2014-02-20 | Opx Biotechnologies, Inc. | Micoorganisms and Methods for the Production of Fatty Acids and Fatty Acid Derived Products |
| GB201300354D0 (en) | 2013-01-09 | 2013-02-20 | Basf Pharma Callanish Ltd | Multi-step separation process |
| WO2014116754A1 (en) | 2013-01-23 | 2014-07-31 | Iowa State University Research Foundation, Inc. | Materials and methods for characterizing and using kasiii for production of bi-functional fatty acids |
| US10184140B2 (en) | 2013-01-23 | 2019-01-22 | Iowa State University Research Foundation, Inc. | Materials and methods for production of bi-functional fatty acids in recombinant bacteria |
| US9816079B2 (en) | 2013-01-29 | 2017-11-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| US9567615B2 (en) | 2013-01-29 | 2017-02-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| EP2976141A4 (en) | 2013-03-15 | 2016-10-05 | Cargill Inc | FLASHING FOR PRODUCTION CLEANING AND RECOVERY |
| US9783836B2 (en) | 2013-03-15 | 2017-10-10 | Terravia Holdings, Inc. | Thioesterases and cells for production of tailored oils |
| WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
| US9290749B2 (en) | 2013-03-15 | 2016-03-22 | Solazyme, Inc. | Thioesterases and cells for production of tailored oils |
| WO2015010103A2 (en) * | 2013-07-19 | 2015-01-22 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| SG11201602638SA (en) | 2013-10-04 | 2016-05-30 | Solazyme Inc | Tailored oils |
| MX2016005718A (es) | 2013-11-01 | 2016-12-08 | Conagen Inc | Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas. |
| TW201525136A (zh) | 2013-11-26 | 2015-07-01 | Dow Agrosciences Llc | 利用破囊壺菌PUFA合成酶於油籽作物中生成ω-3長鏈多不飽和脂肪酸 |
| AU2014360086B2 (en) | 2013-12-05 | 2018-04-19 | Genomatica, Inc. | Microbial production of fatty amines |
| CA3241340A1 (en) | 2013-12-18 | 2015-06-25 | Grains Research And Development Corporation | Lipid comprising long chain polyunsaturated fatty acids |
| WO2015116671A2 (en) * | 2014-01-28 | 2015-08-06 | Dsm Ip Assets B.V. | Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| EP3167053B1 (en) | 2014-07-10 | 2019-10-09 | Corbion Biotech, Inc. | Novel ketoacyl acp synthase genes and uses thereof |
| US9765368B2 (en) | 2014-07-24 | 2017-09-19 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| US10125382B2 (en) | 2014-09-18 | 2018-11-13 | Corbion Biotech, Inc. | Acyl-ACP thioesterases and mutants thereof |
| US10570427B2 (en) * | 2014-10-31 | 2020-02-25 | Lanzatech New Zealand Limited | Fermentation process for the production of lipids |
| WO2016137897A1 (en) * | 2015-02-24 | 2016-09-01 | William Marsh Rice University | Kasiii-free fa synthesis |
| WO2016200720A1 (en) | 2015-06-06 | 2016-12-15 | Dsm Ip Assets B.V. | Production of polyunsaturated fatty acids (pufas) using a novel modular docosahexaenoic acid (dha) synthase |
| WO2017117425A1 (en) * | 2015-12-31 | 2017-07-06 | Synthetic Genomics, Inc. | Expression of type i fatty acid synthase genes in eukaryotic algae |
| EP3377057A4 (en) | 2016-01-07 | 2018-12-05 | Conagen Inc. | Methods of making capsinoids by biosynthetic processes |
| DK3487986T3 (da) | 2016-07-19 | 2021-07-26 | Conagen Inc | Fremgangsmåde til mikrobiel fremstilling af specifikke naturlige capsaicinoider |
| CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
| US11352601B2 (en) | 2017-07-27 | 2022-06-07 | University Of Florida Research Foundation, Incorporated | Cyanobacterial hosts and methods for producing chemicals |
| WO2019164294A1 (ko) * | 2018-02-21 | 2019-08-29 | 경상북도 | 신규한 1-octen-3-ol을 생산하는 형질전환 효모 및 그 제조방법 |
| KR102318983B1 (ko) * | 2018-02-21 | 2021-11-01 | 경상북도 | 신규한 1-octen-3-ol을 생산하는 형질전환 효모 및 그 제조방법 |
| CN112661821B (zh) * | 2021-01-21 | 2022-04-12 | 江南大学 | 一种柠檬酸转运蛋白及其在脂质合成中的应用 |
| US20250034601A1 (en) * | 2021-10-25 | 2025-01-30 | Purdue Research Foundation | Heterodimeric benzaldehyde synthase, methods of producing, and uses thereof |
| EP4469588A1 (en) | 2022-01-25 | 2024-12-04 | DSM IP Assets B.V. | Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production |
| WO2025238190A1 (en) | 2024-05-15 | 2025-11-20 | Dsm Ip Assets B.V. | Spray-dried powders having high pufa content |
| CN119193346A (zh) * | 2024-11-26 | 2024-12-27 | 南京师范大学 | 一种过表达溶血磷脂酸酰基转移酶基因的裂殖壶菌基因工程菌株及其构建方法和应用 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8317248D0 (en) | 1983-06-24 | 1983-07-27 | Wyeth John & Brother Ltd | Fat compositions |
| US5246841A (en) | 1986-12-26 | 1993-09-21 | Sagami Chemical Research Center | Microbial process for production of eicosapentaenoic acid |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US5130242A (en) * | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| US5601860A (en) | 1990-11-30 | 1997-02-11 | American Home Products Corporation | Corandomized fat compositions for infant formulas |
| US5639790A (en) * | 1991-05-21 | 1997-06-17 | Calgene, Inc. | Plant medium-chain thioesterases |
| DK0616644T3 (da) | 1991-12-04 | 2003-10-27 | Du Pont | Fedtsyredesaturase-gener fra planter |
| US5683898A (en) | 1992-05-15 | 1997-11-04 | Sagami Chemical Research Center | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid |
| EP0594868A4 (en) | 1992-05-15 | 1997-01-02 | Sagami Chem Res | Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid |
| US5798259A (en) * | 1992-05-15 | 1998-08-25 | Sagami Chemical Research Center | Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid |
| US5310242A (en) * | 1992-09-28 | 1994-05-10 | Golder Kimberly A | Portable infant seat |
| US6372965B1 (en) | 1992-11-17 | 2002-04-16 | E.I. Du Pont De Nemours And Company | Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants |
| DE4323727A1 (de) | 1993-07-15 | 1995-03-09 | Boehringer Mannheim Gmbh | Verfahren zur Identifizierung von menschlichen und tierischen Zellen mit der Fähigkeit zu unbegrenzter Proliferation oder zur Tumorbildung |
| US5672491A (en) | 1993-09-20 | 1997-09-30 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
| AU4400196A (en) | 1995-01-13 | 1996-07-31 | Sagami Chemical Research Center | Genes coding for biosynthetic enzyme group for icosapentaenoic acid and process for producing icosapentaenoic acid |
| DE69637953D1 (de) | 1995-04-17 | 2009-07-30 | Nat Inst Of Advanced Ind Scien | Hoch ungesättigte fettsäurenproduzierende mikroorganismen und verfahren zur herstellung von hoch ungesättigten fettsäuren durch verwendung dieser mikroorganismen |
| AR006830A1 (es) | 1996-04-26 | 1999-09-29 | Du Pont | Aceite de soja con alta estabilidad oxidativa |
| EP0913473A4 (en) | 1996-07-10 | 2000-12-06 | Sagami Chem Res | METHOD FOR PRODUCING EICOSAPENTIC ACID BY GENETIC RECOMBINATION |
| US6033883A (en) | 1996-12-18 | 2000-03-07 | Kosan Biosciences, Inc. | Production of polyketides in bacteria and yeast |
| SA98190002B1 (ar) | 1997-03-28 | 2006-06-20 | ذي يونيفيرسيتي اوف تننيسي ريسيرش كوربوريشن | استخدام أحماض دهنية تحتوي على عدة روابط غير مشبعة polyunsaturated fatty acids لتقليل حدوث الالتهاب المعوي القولوني الناخر incidence of necrotizing enterocolitis |
| PL336077A1 (en) | 1997-04-11 | 2000-06-05 | Calgene Llc | Methods of and compositions for synthesising long-chain polyunsaturated fatty acids in plants |
| US6432684B1 (en) | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
| US6051754A (en) | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| IN1998CH01219A (en) * | 1997-06-04 | 2005-03-04 | Calgene Llc | Production of polyunsaturated fatty acid by expression of polyketide-like synthesis genes in plants |
| US6013665A (en) | 1997-12-16 | 2000-01-11 | Abbott Laboratories | Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides |
| US6677145B2 (en) | 1998-09-02 | 2004-01-13 | Abbott Laboratories | Elongase genes and uses thereof |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7271315B2 (en) * | 1999-01-14 | 2007-09-18 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| AU2001268296B2 (en) * | 2000-06-08 | 2006-05-25 | Miami University | Fatty acid elongase 3-ketoacyl coa synthase polypeptides |
| US20040010817A1 (en) * | 2000-07-21 | 2004-01-15 | Washington State University Research Foundation | Plant acyl-CoA synthetases |
| CA2421267C (en) | 2000-09-28 | 2009-01-06 | Bioriginal Food & Science Corporation | Fad4, fad5, fad5-2, and fad6, novel fatty acid desaturase family members and uses thereof |
| US6912470B2 (en) | 2001-05-21 | 2005-06-28 | Ecopia Biosciences, Inc. | Genes and proteins involved in the biosynthesis of enediyne ring structures |
| TWI350854B (en) * | 2001-04-16 | 2011-10-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| TWI337619B (en) | 2001-04-16 | 2011-02-21 | Martek Biosciences Corp | Pufa polyketide synthase systems and uses thereof |
| US20040005672A1 (en) | 2002-02-22 | 2004-01-08 | Santi Daniel V. | Heterologous production of polyketides |
| GB2385852A (en) * | 2002-02-27 | 2003-09-03 | Rothamsted Ex Station | Delta 6-desaturases from Primulaceae |
| ATE495263T1 (de) * | 2002-03-16 | 2011-01-15 | Univ York | Transgene pflanzen, die fettsäurebiosynthese enzyme exprimieren |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| MXPA05010214A (es) | 2003-03-26 | 2005-12-14 | Martek Biosciences Corp | Sistemas de sintasa de poliquetida pufa y uso de los mismos. |
| AU2004225838B2 (en) | 2003-03-31 | 2009-11-05 | University Of Bristol | Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7208590B2 (en) * | 2003-07-15 | 2007-04-24 | Abbott Laboratories | Genes involved in polyketide synthase pathways and uses thereof |
| DE102004017370A1 (de) | 2004-04-08 | 2005-10-27 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | PUFA-PKS Gene aus Ulkenia |
| DE102004060340A1 (de) | 2004-07-16 | 2006-02-09 | Basf Plant Science Gmbh | Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen |
| WO2006034228A2 (en) | 2004-09-20 | 2006-03-30 | Basf Plant Science Gmbh | Arabidopsis genes encoding proteins involved in sugar and lipid metabolism and methods of use |
| GB0421937D0 (en) * | 2004-10-02 | 2004-11-03 | Univ York | Acyl CoA synthetases |
| WO2006135866A2 (en) * | 2005-06-10 | 2006-12-21 | Martek Biosciences Corporation | Pufa polyketide synthase systems and uses thereof |
| US7759548B2 (en) * | 2006-03-15 | 2010-07-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems |
| FR2904328B1 (fr) * | 2006-07-27 | 2008-10-24 | St Microelectronics Sa | Depot par adsorption sous un champ electrique |
-
2007
- 2007-03-15 US US11/686,856 patent/US7759548B2/en active Active
- 2007-03-15 AU AU2007226510A patent/AU2007226510B2/en not_active Ceased
- 2007-03-15 TW TW096108936A patent/TWI504748B/zh not_active IP Right Cessation
- 2007-03-15 EP EP13159107.5A patent/EP2653557A1/en not_active Withdrawn
- 2007-03-15 MX MX2012003219A patent/MX339812B/es unknown
- 2007-03-15 US US11/686,872 patent/US20070220634A1/en not_active Abandoned
- 2007-03-15 EP EP07758640.2A patent/EP2001277B9/en active Active
- 2007-03-15 EP EP07758641A patent/EP2004835A4/en not_active Withdrawn
- 2007-03-15 JP JP2009500611A patent/JP5227302B2/ja not_active Expired - Fee Related
- 2007-03-15 KR KR1020087025101A patent/KR101506347B1/ko not_active Expired - Fee Related
- 2007-03-15 MX MX2008011783A patent/MX340759B/es active IP Right Grant
- 2007-03-15 AU AU2007226511A patent/AU2007226511A1/en not_active Abandoned
- 2007-03-15 WO PCT/US2007/064106 patent/WO2007106905A2/en not_active Ceased
- 2007-03-15 ES ES07758640.2T patent/ES2527875T3/es active Active
- 2007-03-15 KR KR1020137023972A patent/KR101524398B1/ko not_active Expired - Fee Related
- 2007-03-15 WO PCT/US2007/064104 patent/WO2007106903A2/en not_active Ceased
- 2007-03-15 BR BRPI0709317-9A2A patent/BRPI0709317A2/pt not_active IP Right Cessation
- 2007-03-15 TW TW096108937A patent/TW200813222A/zh unknown
- 2007-03-15 CN CN201410121112.2A patent/CN104073505A/zh active Pending
- 2007-03-15 US US11/686,850 patent/US20070245431A1/en not_active Abandoned
- 2007-03-15 KR KR1020087025100A patent/KR101517243B1/ko not_active Expired - Fee Related
- 2007-03-15 WO PCT/US2007/064105 patent/WO2007106904A2/en not_active Ceased
- 2007-03-15 JP JP2009500612A patent/JP2009529891A/ja active Pending
- 2007-03-15 CA CA002646317A patent/CA2646317A1/en not_active Abandoned
- 2007-03-15 MX MX2008011784A patent/MX2008011784A/es active IP Right Grant
- 2007-03-15 CA CA002647150A patent/CA2647150A1/en not_active Abandoned
-
2008
- 2008-09-14 IL IL194078A patent/IL194078A/en not_active IP Right Cessation
- 2008-09-14 IL IL194077A patent/IL194077A/en not_active IP Right Cessation
-
2010
- 2010-06-08 US US12/796,100 patent/US8426686B2/en active Active
-
2012
- 2012-11-28 JP JP2012259228A patent/JP2013116104A/ja active Pending
-
2013
- 2013-03-21 US US13/848,070 patent/US9382521B2/en active Active - Reinstated
- 2013-10-22 JP JP2013219079A patent/JP2014087338A/ja not_active Withdrawn
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX339812B (es) | Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa. | |
| Sun et al. | Enhancement of lipid accumulation in microalgae by metabolic engineering | |
| Ng et al. | Recent developments on genetic engineering of microalgae for biofuels and bio‐based chemicals | |
| Shi et al. | Reactive oxygen species-mediated cellular stress response and lipid accumulation in oleaginous microorganisms: the state of the art and future perspectives | |
| Yu et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae | |
| Balamurugan et al. | Occurrence of plastidial triacylglycerol synthesis and the potential regulatory role of AGPAT in the model diatom Phaeodactylum tricornutum | |
| Haslam et al. | Synthetic redesign of plant lipid metabolism | |
| Avidan et al. | Enhanced acetyl-CoA production is associated with increased triglyceride accumulation in the green alga Chlorella desiccata | |
| MX2009012395A (es) | Sistema de sintasa de policetida de acido graso poli insaturado (pufa) quimericos y usos de los mismos. | |
| Bansal et al. | Camelina sativa: An ideal platform for the metabolic engineering and field production of industrial lipids | |
| Beacham et al. | Altered lipid accumulation in Nannochloropsis salina CCAP849/3 following EMS and UV induced mutagenesis | |
| Gomma et al. | Improvement in oil production by increasing malonyl-CoA and glycerol-3-phosphate pools in Scenedesmus quadricauda | |
| JP2013116104A5 (OSRAM) | ||
| MY165098A (en) | Production of dha and other lc-pufas in plants | |
| WO2016007862A3 (en) | Ketoacyl acp synthase genes and uses thereof | |
| Ravindran et al. | Recent advances and future prospects of microalgal lipid biotechnology | |
| WO2012087982A3 (en) | Modified photosynthetic microorganisms for producing lipids | |
| WO2007149583A3 (en) | Acyltransferases for altering lipid production on plants | |
| WO2006135866A3 (en) | Pufa polyketide synthase systems and uses thereof | |
| Galán et al. | Microbial oils as nutraceuticals and animal feeds | |
| Ujihara et al. | Identification of a novel type of polyunsaturated fatty acid synthase involved in arachidonic acid biosynthesis | |
| WO2007090121A3 (en) | Phosphopantetheinyl transferases from bacteria | |
| Walsh et al. | Producing the omega‐3 fatty acids DHA and EPA in oilseed crops | |
| CA2948896A1 (en) | Method for optimizing production of eicosapentaenoic acid (epa) in a recombinant host | |
| Zhang et al. | Association of triacylglyceride content and transcript abundance of genes involving in lipid synthesis of nitrogen deficient Phaeodactylum tricornutum |