MX339812B - Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa. - Google Patents

Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa.

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Publication number
MX339812B
MX339812B MX2012003219A MX2012003219A MX339812B MX 339812 B MX339812 B MX 339812B MX 2012003219 A MX2012003219 A MX 2012003219A MX 2012003219 A MX2012003219 A MX 2012003219A MX 339812 B MX339812 B MX 339812B
Authority
MX
Mexico
Prior art keywords
organisms
pufas
fatty acid
express
nucleic acid
Prior art date
Application number
MX2012003219A
Other languages
English (en)
Spanish (es)
Inventor
G Metz James
Casey Lippmeier James
M Kuner Jerry
Original Assignee
Dsm Ip Assets B V *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets B V * filed Critical Dsm Ip Assets B V *
Publication of MX339812B publication Critical patent/MX339812B/es

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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N5/04Plant cells or tissues
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    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
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    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
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  • Diabetes (AREA)
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MX2012003219A 2006-03-15 2007-03-15 Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa. MX339812B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78320506P 2006-03-15 2006-03-15
US78461606P 2006-03-21 2006-03-21
PCT/US2007/064104 WO2007106903A2 (en) 2006-03-15 2007-03-15 Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems

Publications (1)

Publication Number Publication Date
MX339812B true MX339812B (es) 2016-06-08

Family

ID=38510298

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2012003219A MX339812B (es) 2006-03-15 2007-03-15 Produccion de acido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policetido pufa.
MX2008011783A MX340759B (es) 2006-03-15 2007-03-15 Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados.
MX2008011784A MX2008011784A (es) 2006-03-15 2007-03-15 Produccion de ácido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policétido pufa.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2008011783A MX340759B (es) 2006-03-15 2007-03-15 Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados.
MX2008011784A MX2008011784A (es) 2006-03-15 2007-03-15 Produccion de ácido graso poli-insaturado en organismos heterologos usando sistemas de sintasa de policétido pufa.

Country Status (13)

Country Link
US (5) US7759548B2 (OSRAM)
EP (3) EP2653557A1 (OSRAM)
JP (4) JP5227302B2 (OSRAM)
KR (3) KR101506347B1 (OSRAM)
CN (1) CN104073505A (OSRAM)
AU (2) AU2007226510B2 (OSRAM)
BR (1) BRPI0709317A2 (OSRAM)
CA (2) CA2646317A1 (OSRAM)
ES (1) ES2527875T3 (OSRAM)
IL (2) IL194078A (OSRAM)
MX (3) MX339812B (OSRAM)
TW (2) TWI504748B (OSRAM)
WO (3) WO2007106905A2 (OSRAM)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
TWI350854B (en) 2001-04-16 2011-10-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CA3023314C (en) 2004-04-22 2019-12-10 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US7759548B2 (en) * 2006-03-15 2010-07-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
CN101903513B (zh) * 2007-01-12 2013-08-21 科罗拉多大学董事会法人 增强微生物对产生的有机化学物质的耐受性的组合物和方法
KR101504618B1 (ko) 2007-06-01 2015-03-23 솔라짐, 인코포레이티드 미생물에서 오일의 생성
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
WO2009097331A1 (en) * 2008-01-28 2009-08-06 The Board Of Regents Of The University Of Oklahoma Very long chain polyunsaturated fatty acids, methods of production, and uses
WO2010019813A2 (en) * 2008-08-13 2010-02-18 Sapphire Energy, Inc. Production of fatty actds by genetically modified photosynthetic organisms
US20110218354A1 (en) * 2008-09-19 2011-09-08 President And Fellows Of Harvard College Photoautotrophic Adipogenesis Technology (Phat)
ES2644883T3 (es) 2008-11-18 2017-11-30 Commonwealth Scientific And Industrial Research Organisation Enzimas y métodos para producir ácidos grasos omega-3
ES2583639T3 (es) 2008-11-28 2016-09-21 Terravia Holdings, Inc. Producción de aceites específicos en microorganismos heterótrofos
CN102325874A (zh) * 2008-12-19 2012-01-18 α-J研究有限合伙公司 通过使细胞增殖与海藻产品生产分离来最优化海藻产品的生产
TW201028472A (en) * 2009-01-13 2010-08-01 Alpha J Res Ltd Partnership Use of plant growth regulators to enhance algae growth for the production of added value products
CA2755667C (en) * 2009-03-16 2018-06-12 Martek Biosciences Corporation Protein production in microorganisms of the phylum labyrinthulomycota
ES2717102T3 (es) 2009-03-19 2019-06-19 Dsm Ip Assets Bv Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos
JP2012529277A (ja) * 2009-06-08 2012-11-22 ロザムステッド リサーチ リミテッド 新規の脂肪酸伸長成分およびその使用
BRPI1009593A2 (pt) * 2009-06-30 2015-08-18 Solae Llc Composição alimentícia e método de utilização do óleo de soja enriquecido com das"
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
CN102695799A (zh) 2009-09-27 2012-09-26 Opx生物工艺学公司 用于制备3-羟基丙酸和其它产物的方法
US9012197B2 (en) * 2009-12-28 2015-04-21 Merial, Inc. Production of hemagglutinin-neuraminidase protein in microalgae
EP4130273B1 (en) * 2009-12-28 2024-06-12 Sanofi Vaccine Technologies, S.A.S. Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof
PE20130491A1 (es) 2009-12-30 2013-05-02 Basf Pharma Callanish Ltd Proceso simulado de separacion cromatografica de lecho movil para la purificacion de acidos grasos poliinsaturados
AR079852A1 (es) * 2010-01-07 2012-02-22 Aedenswil Basf Agro B V Arnhem Nl Zweigniederlassung W Plantas tolerantes a herbicidas
MX2012008700A (es) * 2010-01-27 2012-10-05 Univ Colorado Regents Reduccion con microorganismos de productos quimicos de alto valor y composiciones, metodos y sistemas relacionados.
KR101758591B1 (ko) * 2010-02-01 2017-07-14 산토리 홀딩스 가부시키가이샤 아실-CoA 신세타제 호몰로그를 코딩하는 폴리뉴클레오타이드 및 그 용도
US8372465B2 (en) 2010-02-17 2013-02-12 Bunge Oils, Inc. Oil compositions of stearidonic acid
TW201144442A (en) * 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
US11236351B2 (en) * 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
SG10201504187YA (en) 2010-05-28 2015-06-29 Solazyme Inc Tailored oils produced from recombinant heterotrophic microorganisms
AU2013202057B2 (en) * 2010-06-25 2016-01-28 Basf Plant Science Company Gmbh Acyltransferases and uses therof in fatty acid production
EP2585603B1 (en) 2010-06-25 2017-12-20 BASF Plant Science Company GmbH Acyltransferases and uses therof in fatty acid production
CA3024641A1 (en) 2010-11-03 2012-05-10 Corbion Biotech, Inc. Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
JP6071904B2 (ja) 2011-02-02 2017-02-01 テラヴィア ホールディングス, インコーポレイテッド 組み換え油産生微生物から生成される用途に応じた油
CN102250864B (zh) * 2011-05-03 2013-03-20 中国农业大学 亚油酸异构酶在脱氢和异构方面的双重用途
AU2012253803A1 (en) 2011-05-06 2013-12-05 Terravia Holdings, Inc. Genetically engineered microorganisms that metabolize xylose
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
TW201307553A (zh) * 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術
BR112014002418A2 (pt) * 2011-08-04 2017-03-14 Suntory Holdings Ltd proteína tendo atividade para promover alongamento da cadeia de ácido graxo, gene que codifica a mesma e seu uso
WO2013077420A1 (ja) * 2011-11-25 2013-05-30 独立行政法人農業生物資源研究所 植物の形質転換体、植物の形質転換方法、並びに該方法に用いられるベクター
JP6499577B2 (ja) 2012-04-18 2019-04-10 テラヴィア ホールディングス, インコーポレイテッド 調整油
US9719114B2 (en) 2012-04-18 2017-08-01 Terravia Holdings, Inc. Tailored oils
DE102012207921A1 (de) 2012-05-11 2013-11-14 Evonik Industries Ag Mehrstufiges Syntheseverfahren mit Synthesegas
CA3082388A1 (en) 2012-06-15 2013-12-19 Commonwealth Scientific And Industrial Research Organisation Genetic constructs for producing long chain polyunsaturated fatty acids in plant cells
US20140051136A1 (en) * 2012-08-10 2014-02-20 Opx Biotechnologies, Inc. Micoorganisms and Methods for the Production of Fatty Acids and Fatty Acid Derived Products
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
WO2014116754A1 (en) 2013-01-23 2014-07-31 Iowa State University Research Foundation, Inc. Materials and methods for characterizing and using kasiii for production of bi-functional fatty acids
US10184140B2 (en) 2013-01-23 2019-01-22 Iowa State University Research Foundation, Inc. Materials and methods for production of bi-functional fatty acids in recombinant bacteria
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9567615B2 (en) 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
WO2015010103A2 (en) * 2013-07-19 2015-01-22 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
SG11201602638SA (en) 2013-10-04 2016-05-30 Solazyme Inc Tailored oils
MX2016005718A (es) 2013-11-01 2016-12-08 Conagen Inc Metodos de uso de acil-coa sintetasa para produccion biosintetica de acil-coas.
TW201525136A (zh) 2013-11-26 2015-07-01 Dow Agrosciences Llc 利用破囊壺菌PUFA合成酶於油籽作物中生成ω-3長鏈多不飽和脂肪酸
AU2014360086B2 (en) 2013-12-05 2018-04-19 Genomatica, Inc. Microbial production of fatty amines
CA3241340A1 (en) 2013-12-18 2015-06-25 Grains Research And Development Corporation Lipid comprising long chain polyunsaturated fatty acids
WO2015116671A2 (en) * 2014-01-28 2015-08-06 Dsm Ip Assets B.V. Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases
CA2953008C (en) 2014-06-27 2024-03-19 Nuseed Pty Ltd Lipid comprising docosapentaenoic acid
EP3167053B1 (en) 2014-07-10 2019-10-09 Corbion Biotech, Inc. Novel ketoacyl acp synthase genes and uses thereof
US9765368B2 (en) 2014-07-24 2017-09-19 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
US10125382B2 (en) 2014-09-18 2018-11-13 Corbion Biotech, Inc. Acyl-ACP thioesterases and mutants thereof
US10570427B2 (en) * 2014-10-31 2020-02-25 Lanzatech New Zealand Limited Fermentation process for the production of lipids
WO2016137897A1 (en) * 2015-02-24 2016-09-01 William Marsh Rice University Kasiii-free fa synthesis
WO2016200720A1 (en) 2015-06-06 2016-12-15 Dsm Ip Assets B.V. Production of polyunsaturated fatty acids (pufas) using a novel modular docosahexaenoic acid (dha) synthase
WO2017117425A1 (en) * 2015-12-31 2017-07-06 Synthetic Genomics, Inc. Expression of type i fatty acid synthase genes in eukaryotic algae
EP3377057A4 (en) 2016-01-07 2018-12-05 Conagen Inc. Methods of making capsinoids by biosynthetic processes
DK3487986T3 (da) 2016-07-19 2021-07-26 Conagen Inc Fremgangsmåde til mikrobiel fremstilling af specifikke naturlige capsaicinoider
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
US11352601B2 (en) 2017-07-27 2022-06-07 University Of Florida Research Foundation, Incorporated Cyanobacterial hosts and methods for producing chemicals
WO2019164294A1 (ko) * 2018-02-21 2019-08-29 경상북도 신규한 1-octen-3-ol을 생산하는 형질전환 효모 및 그 제조방법
KR102318983B1 (ko) * 2018-02-21 2021-11-01 경상북도 신규한 1-octen-3-ol을 생산하는 형질전환 효모 및 그 제조방법
CN112661821B (zh) * 2021-01-21 2022-04-12 江南大学 一种柠檬酸转运蛋白及其在脂质合成中的应用
US20250034601A1 (en) * 2021-10-25 2025-01-30 Purdue Research Foundation Heterodimeric benzaldehyde synthase, methods of producing, and uses thereof
EP4469588A1 (en) 2022-01-25 2024-12-04 DSM IP Assets B.V. Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production
WO2025238190A1 (en) 2024-05-15 2025-11-20 Dsm Ip Assets B.V. Spray-dried powders having high pufa content
CN119193346A (zh) * 2024-11-26 2024-12-27 南京师范大学 一种过表达溶血磷脂酸酰基转移酶基因的裂殖壶菌基因工程菌株及其构建方法和应用

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8317248D0 (en) 1983-06-24 1983-07-27 Wyeth John & Brother Ltd Fat compositions
US5246841A (en) 1986-12-26 1993-09-21 Sagami Chemical Research Center Microbial process for production of eicosapentaenoic acid
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5601860A (en) 1990-11-30 1997-02-11 American Home Products Corporation Corandomized fat compositions for infant formulas
US5639790A (en) * 1991-05-21 1997-06-17 Calgene, Inc. Plant medium-chain thioesterases
DK0616644T3 (da) 1991-12-04 2003-10-27 Du Pont Fedtsyredesaturase-gener fra planter
US5683898A (en) 1992-05-15 1997-11-04 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
EP0594868A4 (en) 1992-05-15 1997-01-02 Sagami Chem Res Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid
US5798259A (en) * 1992-05-15 1998-08-25 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
US5310242A (en) * 1992-09-28 1994-05-10 Golder Kimberly A Portable infant seat
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
DE4323727A1 (de) 1993-07-15 1995-03-09 Boehringer Mannheim Gmbh Verfahren zur Identifizierung von menschlichen und tierischen Zellen mit der Fähigkeit zu unbegrenzter Proliferation oder zur Tumorbildung
US5672491A (en) 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
AU4400196A (en) 1995-01-13 1996-07-31 Sagami Chemical Research Center Genes coding for biosynthetic enzyme group for icosapentaenoic acid and process for producing icosapentaenoic acid
DE69637953D1 (de) 1995-04-17 2009-07-30 Nat Inst Of Advanced Ind Scien Hoch ungesättigte fettsäurenproduzierende mikroorganismen und verfahren zur herstellung von hoch ungesättigten fettsäuren durch verwendung dieser mikroorganismen
AR006830A1 (es) 1996-04-26 1999-09-29 Du Pont Aceite de soja con alta estabilidad oxidativa
EP0913473A4 (en) 1996-07-10 2000-12-06 Sagami Chem Res METHOD FOR PRODUCING EICOSAPENTIC ACID BY GENETIC RECOMBINATION
US6033883A (en) 1996-12-18 2000-03-07 Kosan Biosciences, Inc. Production of polyketides in bacteria and yeast
SA98190002B1 (ar) 1997-03-28 2006-06-20 ذي يونيفيرسيتي اوف تننيسي ريسيرش كوربوريشن استخدام أحماض دهنية تحتوي على عدة روابط غير مشبعة polyunsaturated fatty acids لتقليل حدوث الالتهاب المعوي القولوني الناخر incidence of necrotizing enterocolitis
PL336077A1 (en) 1997-04-11 2000-06-05 Calgene Llc Methods of and compositions for synthesising long-chain polyunsaturated fatty acids in plants
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
IN1998CH01219A (en) * 1997-06-04 2005-03-04 Calgene Llc Production of polyunsaturated fatty acid by expression of polyketide-like synthesis genes in plants
US6013665A (en) 1997-12-16 2000-01-11 Abbott Laboratories Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US7211418B2 (en) * 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7217856B2 (en) * 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7271315B2 (en) * 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
AU2001268296B2 (en) * 2000-06-08 2006-05-25 Miami University Fatty acid elongase 3-ketoacyl coa synthase polypeptides
US20040010817A1 (en) * 2000-07-21 2004-01-15 Washington State University Research Foundation Plant acyl-CoA synthetases
CA2421267C (en) 2000-09-28 2009-01-06 Bioriginal Food & Science Corporation Fad4, fad5, fad5-2, and fad6, novel fatty acid desaturase family members and uses thereof
US6912470B2 (en) 2001-05-21 2005-06-28 Ecopia Biosciences, Inc. Genes and proteins involved in the biosynthesis of enediyne ring structures
TWI350854B (en) * 2001-04-16 2011-10-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
TWI337619B (en) 2001-04-16 2011-02-21 Martek Biosciences Corp Pufa polyketide synthase systems and uses thereof
US20040005672A1 (en) 2002-02-22 2004-01-08 Santi Daniel V. Heterologous production of polyketides
GB2385852A (en) * 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
ATE495263T1 (de) * 2002-03-16 2011-01-15 Univ York Transgene pflanzen, die fettsäurebiosynthese enzyme exprimieren
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
MXPA05010214A (es) 2003-03-26 2005-12-14 Martek Biosciences Corp Sistemas de sintasa de poliquetida pufa y uso de los mismos.
AU2004225838B2 (en) 2003-03-31 2009-11-05 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7208590B2 (en) * 2003-07-15 2007-04-24 Abbott Laboratories Genes involved in polyketide synthase pathways and uses thereof
DE102004017370A1 (de) 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
WO2006034228A2 (en) 2004-09-20 2006-03-30 Basf Plant Science Gmbh Arabidopsis genes encoding proteins involved in sugar and lipid metabolism and methods of use
GB0421937D0 (en) * 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
WO2006135866A2 (en) * 2005-06-10 2006-12-21 Martek Biosciences Corporation Pufa polyketide synthase systems and uses thereof
US7759548B2 (en) * 2006-03-15 2010-07-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using PUFA polyketide synthase systems
FR2904328B1 (fr) * 2006-07-27 2008-10-24 St Microelectronics Sa Depot par adsorption sous un champ electrique

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