MX2023012498A - Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico. - Google Patents

Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico.

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Publication number
MX2023012498A
MX2023012498A MX2023012498A MX2023012498A MX2023012498A MX 2023012498 A MX2023012498 A MX 2023012498A MX 2023012498 A MX2023012498 A MX 2023012498A MX 2023012498 A MX2023012498 A MX 2023012498A MX 2023012498 A MX2023012498 A MX 2023012498A
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Mexico
Prior art keywords
aav
serum
vector
associated viral
cell culture
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MX2023012498A
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English (en)
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John Fraser Wright
Guang Qu
Lin Lu
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Spark Therapeutics Inc
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Publication of MX2023012498A publication Critical patent/MX2023012498A/es

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Abstract

Se dan a conocer métodos y composiciones para transfectar células con plásmidos. En ciertas modalidades, se dan a conocer métodos y composiciones en los cuales la eficiencia de transfección se incrementa significativamente al poner en contacto las células que se transducen con polietilenimina (PEI) que se encuentra libre de ácido nucleico durante el proceso de transfección. También se dan a conocer vectores virales adenoasociados terapéuticamente útiles, generados de acuerdo con los métodos y composiciones dados a conocer.
MX2023012498A 2015-12-01 2018-05-31 Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico. MX2023012498A (es)

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US201562261815P 2015-12-01 2015-12-01

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MX2023012498A true MX2023012498A (es) 2023-11-03

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ID=58797705

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MX2018006682A MX2018006682A (es) 2015-12-01 2016-12-01 Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico.
MX2023012498A MX2023012498A (es) 2015-12-01 2018-05-31 Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico.

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US (1) US20190292561A1 (es)
EP (1) EP3384015A4 (es)
JP (2) JP7444521B2 (es)
KR (1) KR20180091863A (es)
CN (1) CN108603174A (es)
AU (2) AU2016362317B2 (es)
BR (1) BR112018011193A2 (es)
CA (1) CA3006309A1 (es)
CO (1) CO2018006699A2 (es)
IL (1) IL259595B2 (es)
MX (2) MX2018006682A (es)
PE (2) PE20240371A1 (es)
PH (1) PH12018501168A1 (es)
RU (1) RU2766583C2 (es)
SG (2) SG11201804400SA (es)
WO (1) WO2017096039A1 (es)

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IL259595B2 (en) 2024-01-01
JP2022071049A (ja) 2022-05-13
RU2018123502A3 (es) 2020-04-20
AU2016362317B2 (en) 2023-03-16
CA3006309A1 (en) 2017-06-08
RU2766583C2 (ru) 2022-03-15
PE20240371A1 (es) 2024-03-05
AU2016362317A1 (en) 2018-06-14
PE20181534A1 (es) 2018-09-26
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RU2018123502A (ru) 2020-01-14
EP3384015A1 (en) 2018-10-10
EP3384015A4 (en) 2019-05-29
BR112018011193A2 (pt) 2018-11-21
SG11201804400SA (en) 2018-06-28
JP7444521B2 (ja) 2024-03-06
CO2018006699A2 (es) 2018-09-20
MX2018006682A (es) 2018-09-26
US20190292561A1 (en) 2019-09-26
WO2017096039A1 (en) 2017-06-08
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AU2023200992A1 (en) 2023-05-18
CN108603174A (zh) 2018-09-28

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