MX2022015132A - Vacunas combinadas a base de acidos nucleicos. - Google Patents
Vacunas combinadas a base de acidos nucleicos.Info
- Publication number
- MX2022015132A MX2022015132A MX2022015132A MX2022015132A MX2022015132A MX 2022015132 A MX2022015132 A MX 2022015132A MX 2022015132 A MX2022015132 A MX 2022015132A MX 2022015132 A MX2022015132 A MX 2022015132A MX 2022015132 A MX2022015132 A MX 2022015132A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- coronavirus
- pharmaceutical compositions
- infection
- virus
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 241000711573 Coronaviridae Species 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 230000000890 antigenic effect Effects 0.000 abstract 2
- 230000009385 viral infection Effects 0.000 abstract 2
- 208000001528 Coronaviridae Infections Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 229940001442 combination vaccine Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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Abstract
La presente invención está dirigida, entre otras cosas, a composiciones farmacéuticas que comprenden al menos un ácido nucleico que codifica para al menos un péptido o proteína antigénico de un coronavirus, preferiblemente un coronavirus pandémico, y al menos un ácido nucleico que codifica para al menos un péptido o proteína antigénico de un virus adicional, por ejemplo, un virus de la influenza o un virus RSV. Las composiciones farmacéuticas proporcionadas en la presente son adecuadas para usarse en el tratamiento o la profilaxis de una infección con al menos un coronavirus y al menos una infección viral adicional y, por lo tanto, pueden estar comprendidas en una vacuna combinada. Las secuencias de ácido nucleico de las composiciones farmacéuticas y las vacunas combinadas están preferiblemente asociadas con un portador polimérico, una proteína o péptido policatiónico o una nanopartícula lipídica (LNP). La invención también se dirige al primer y segundo uso médico y otros usos médicos de las composiciones farmacéuticas y vacunas combinadas, y a métodos para tratar o prevenir una infección por coronavirus y otra infección por virus.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2020065094 | 2020-05-29 | ||
EP2021052458 | 2021-02-03 | ||
PCT/EP2021/064216 WO2021239880A1 (en) | 2020-05-29 | 2021-05-27 | Nucleic acid based combination vaccines |
Publications (1)
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WO2020002525A1 (en) | 2018-06-27 | 2020-01-02 | Curevac Ag | Novel lassa virus rna molecules and compositions for vaccination |
WO2020002598A1 (en) | 2018-06-28 | 2020-01-02 | Curevac Ag | Bioreactor for rna in vitro transcription |
JP2023512519A (ja) * | 2020-01-31 | 2023-03-27 | ベス イスラエル ディーコネス メディカル センター インコーポレイテッド | コロナウイルス感染症を予防および処置するための組成物および方法-sars-cov-2ワクチン |
CN116113430A (zh) * | 2020-02-04 | 2023-05-12 | 奎尔法克股份有限公司 | 冠状病毒疫苗 |
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2021
- 2021-05-27 CN CN202180058190.0A patent/CN116322758A/zh active Pending
- 2021-05-27 WO PCT/EP2021/064216 patent/WO2021239880A1/en unknown
- 2021-05-27 IL IL298084A patent/IL298084A/en unknown
- 2021-05-27 MX MX2022015132A patent/MX2022015132A/es unknown
- 2021-05-27 EP EP21729297.8A patent/EP3993828A1/en active Pending
- 2021-05-27 CA CA3170740A patent/CA3170740A1/en active Pending
- 2021-05-27 BR BR112022024248A patent/BR112022024248A2/pt unknown
- 2021-05-27 KR KR1020227046214A patent/KR20230053008A/ko active Search and Examination
- 2021-05-27 AU AU2021279312A patent/AU2021279312A1/en active Pending
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2022
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KR20230053008A (ko) | 2023-04-20 |
WO2021239880A1 (en) | 2021-12-02 |
BR112022024248A2 (pt) | 2023-10-10 |
US20220211838A1 (en) | 2022-07-07 |
US20220249654A1 (en) | 2022-08-11 |
CN116322758A (zh) | 2023-06-23 |
AU2021279312A1 (en) | 2022-12-15 |
WO2021239880A9 (en) | 2022-01-13 |
JP2023530229A (ja) | 2023-07-14 |
IL298084A (en) | 2023-01-01 |
EP3993828A1 (en) | 2022-05-11 |
US20220211841A1 (en) | 2022-07-07 |
CA3170740A1 (en) | 2021-12-02 |
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