CO2019000214A2 - Vacuna contra virus de bronquitis infecciosa - Google Patents

Vacuna contra virus de bronquitis infecciosa

Info

Publication number
CO2019000214A2
CO2019000214A2 CONC2019/0000214A CO2019000214A CO2019000214A2 CO 2019000214 A2 CO2019000214 A2 CO 2019000214A2 CO 2019000214 A CO2019000214 A CO 2019000214A CO 2019000214 A2 CO2019000214 A2 CO 2019000214A2
Authority
CO
Colombia
Prior art keywords
present
orf
subject
infectious bronchitis
bronchitis virus
Prior art date
Application number
CONC2019/0000214A
Other languages
English (en)
Inventor
Petrus Josephus Marie Rottier
Beurden Stefanus Johannus Van
Monique Helene Verheije
Egbert Siegfried Mundt
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of CO2019000214A2 publication Critical patent/CO2019000214A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20061—Methods of inactivation or attenuation
    • C12N2770/20062—Methods of inactivation or attenuation by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere, entre otros, a un IBV (virus de bronquitis infecciosa) y a una composición inmunogénica que comprende un IBV, respectivamente, en donde el ORF 3a y/o el ORF 3b y/o el ORF 5a y/o el ORF 5b está inactivado. Por otra parte, la presente invención se refiere a métodos para inmunizar a un sujeto que comprende la administración a un sujeto de la composición inmunogénica de la presente invención. Más aún, la presente invención se refiere a métodos de tratamiento o de prevención de signos clínicos causados por IBV en un sujeto que lo necesita, que comprende la administración al sujeto de una cantidad terapéuticamente eficaz de una composición inmunogénica de acuerdo con la presente invención.
CONC2019/0000214A 2016-06-16 2019-01-11 Vacuna contra virus de bronquitis infecciosa CO2019000214A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16174857 2016-06-16
PCT/EP2017/064442 WO2017216180A1 (en) 2016-06-16 2017-06-13 Vaccine against infectious bronchitis virus

Publications (1)

Publication Number Publication Date
CO2019000214A2 true CO2019000214A2 (es) 2019-01-18

Family

ID=56148179

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0000214A CO2019000214A2 (es) 2016-06-16 2019-01-11 Vacuna contra virus de bronquitis infecciosa

Country Status (12)

Country Link
US (1) US11065328B2 (es)
EP (1) EP3471769A1 (es)
JP (1) JP6874023B2 (es)
KR (1) KR20190021334A (es)
CN (1) CN109641043A (es)
AR (1) AR108829A1 (es)
BR (1) BR112018076234A2 (es)
CO (1) CO2019000214A2 (es)
EA (1) EA201990010A1 (es)
IL (1) IL263550A (es)
MX (1) MX2018015506A (es)
WO (1) WO2017216180A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11999766B2 (en) 2019-05-10 2024-06-04 Boehringer Ingelheim Vetmedia Gmbh Modified S1 subunit of the coronavirus spike protein

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6874023B2 (ja) 2016-06-16 2021-05-19 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ 伝染性気管支炎ウイルスに対するワクチン
BR112021008390A2 (pt) * 2018-10-31 2021-09-28 Boehringer Ingelheim Vetmedica Gmbh Vacina de ibv h52 com proteína da espícula heteróloga
AR116876A1 (es) * 2018-10-31 2021-06-23 Boehringer Ingelheim Vetmedica Gmbh Vacuna de ibv 4/91 con proteína espicular heteróloga
CN110467671B (zh) * 2019-07-04 2022-08-23 中崇信诺生物科技泰州有限公司 一种用spf鸡制备tw1型鸡传染性支气管炎病毒阳性血清的方法
CN111893212A (zh) * 2020-06-17 2020-11-06 安徽农业大学 猫传染性腹膜炎病毒实时荧光定量pcr引物组及试剂盒
US20230272015A1 (en) * 2020-07-17 2023-08-31 Geneone Life Science, Inc. Vaccine composition for preventing severe acute respiratory syndrome coronavirus 2 infection
CN112048006B (zh) * 2020-09-08 2021-04-27 扬州大学 一种替代中和效力测定的elisa方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
ATE463253T1 (de) 2000-02-29 2010-04-15 Wyeth Llc In ovo schutz gegen infektiöse bronchitis
CN102382812A (zh) * 2010-12-15 2012-03-21 江苏省家禽科学研究所 传染性支气管炎病毒h120疫苗株反向遗传操作系统及其操作方法
CN102851257A (zh) * 2012-08-27 2013-01-02 上海启盛生物科技有限公司 一种鸡传染性支气管炎病毒减毒疫苗株及其应用
JP6874023B2 (ja) 2016-06-16 2021-05-19 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ 伝染性気管支炎ウイルスに対するワクチン

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11999766B2 (en) 2019-05-10 2024-06-04 Boehringer Ingelheim Vetmedia Gmbh Modified S1 subunit of the coronavirus spike protein

Also Published As

Publication number Publication date
KR20190021334A (ko) 2019-03-05
AR108829A1 (es) 2018-10-03
MX2018015506A (es) 2019-05-22
JP6874023B2 (ja) 2021-05-19
EP3471769A1 (en) 2019-04-24
CN109641043A (zh) 2019-04-16
JP2019521987A (ja) 2019-08-08
WO2017216180A1 (en) 2017-12-21
EA201990010A1 (ru) 2019-07-31
BR112018076234A2 (pt) 2019-03-26
US11065328B2 (en) 2021-07-20
US20170360921A1 (en) 2017-12-21
IL263550A (en) 2019-01-31

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