MX2021015631A - Moduladores del receptor arilo y metodos para elaborar y usar los mismos. - Google Patents

Moduladores del receptor arilo y metodos para elaborar y usar los mismos.

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Publication number
MX2021015631A
MX2021015631A MX2021015631A MX2021015631A MX2021015631A MX 2021015631 A MX2021015631 A MX 2021015631A MX 2021015631 A MX2021015631 A MX 2021015631A MX 2021015631 A MX2021015631 A MX 2021015631A MX 2021015631 A MX2021015631 A MX 2021015631A
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MX
Mexico
Prior art keywords
methods
making
same
receptor modulators
compounds
Prior art date
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MX2021015631A
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English (en)
Inventor
Salvatore Bellinvia
Salvatore Demartis
Francesca Viti
Original Assignee
Nogra Pharma Ltd
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Publication date
Application filed by Nogra Pharma Ltd filed Critical Nogra Pharma Ltd
Publication of MX2021015631A publication Critical patent/MX2021015631A/es

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Abstract

La presente invención está dirigida generalmente hacia compuestos capaces de unir el receptor de hidrocarburo arilo y modular su actividad, métodos para tratar las afecciones inflamatorias tales como enfermedad de Crohn usando dichos compuestos y composiciones farmacéuticas que comprenden dichos compuestos; también se proporcionan métodos para incrementar los niveles de IL-22 en un sujeto y/o disminuir los niveles de IFN-? en un sujeto.
MX2021015631A 2014-06-27 2017-01-04 Moduladores del receptor arilo y metodos para elaborar y usar los mismos. MX2021015631A (es)

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US201462017959P 2014-06-27 2014-06-27
US201462056054P 2014-09-26 2014-09-26

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MX2021015631A MX2021015631A (es) 2014-06-27 2017-01-04 Moduladores del receptor arilo y metodos para elaborar y usar los mismos.
MX2021015632A MX2021015632A (es) 2014-06-27 2017-01-04 Moduladores del receptor arilo y metodos para elaborar y usar los mismos.

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