MX2021015632A - Moduladores del receptor arilo y metodos para elaborar y usar los mismos. - Google Patents

Moduladores del receptor arilo y metodos para elaborar y usar los mismos.

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Publication number
MX2021015632A
MX2021015632A MX2021015632A MX2021015632A MX2021015632A MX 2021015632 A MX2021015632 A MX 2021015632A MX 2021015632 A MX2021015632 A MX 2021015632A MX 2021015632 A MX2021015632 A MX 2021015632A MX 2021015632 A MX2021015632 A MX 2021015632A
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MX
Mexico
Prior art keywords
methods
making
same
receptor modulators
compounds
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MX2021015632A
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English (en)
Inventor
Salvatore Bellinvia
Salvatore Demartis
Francesca Viti
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Nogra Pharma Ltd
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Application filed by Nogra Pharma Ltd filed Critical Nogra Pharma Ltd
Publication of MX2021015632A publication Critical patent/MX2021015632A/es

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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Abstract

La presente invención está dirigida generalmente hacia compuestos capaces de unir el receptor de hidrocarburo arilo y modular su actividad, métodos para tratar las afecciones inflamatorias tales como enfermedad de Crohn usando dichos compuestos y composiciones farmacéuticas que comprenden dichos compuestos; también se proporcionan métodos para incrementar los niveles de IL-22 en un sujeto y/o disminuir los niveles de IFN-? en un sujeto.
MX2021015632A 2014-06-27 2017-01-04 Moduladores del receptor arilo y metodos para elaborar y usar los mismos. MX2021015632A (es)

Applications Claiming Priority (2)

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US201462017959P 2014-06-27 2014-06-27
US201462056054P 2014-09-26 2014-09-26

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MX2021015631A MX2021015631A (es) 2014-06-27 2017-01-04 Moduladores del receptor arilo y metodos para elaborar y usar los mismos.
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US (2) US11427600B2 (es)
EP (1) EP3160964B1 (es)
JP (4) JP6616790B2 (es)
KR (2) KR20230035446A (es)
CN (3) CN111978319B (es)
AU (3) AU2015279047B2 (es)
BR (1) BR112016030690B1 (es)
CA (1) CA2952897A1 (es)
MA (1) MA40249A (es)
MX (3) MX2017000135A (es)
WO (1) WO2015197861A1 (es)

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CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
MX2017000135A (es) 2014-06-27 2017-04-10 Nogra Pharma Ltd Moduladores del receptor arilo y metodos para elaborar y usar los mismos.
CN112457310A (zh) 2014-12-18 2021-03-09 豪夫迈·罗氏有限公司 四氢-吡啶并[3,4-b]吲哚雌激素受体调节剂及其用途
JP2019001715A (ja) * 2015-10-30 2019-01-10 協和発酵キリン株式会社 三環性化合物
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